Search Results - "Donny Wong"
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Use of carefully titrated ultra‐low doses of alteplase in infected haemothorax caused by initial alteplase use to drain loculated malignant pleural effusion
Published in Respirology case reports (01-09-2023)“…Alteplase as a fibrinolytic can be used to break up fibrin to encourage clot breakdown for clinical use. In the pleural space, it is used for symptomatic…”
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Journal Article -
2
Interaction of Human Apurinic Endonuclease and DNA Polymerase β in the Base Excision Repair Pathway
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-1997)“…Mutagenic abasic (AP) sites are generated directly by DNA-damaging agents or by DNA glycosylases acting in base excision repair. AP sites are corrected via…”
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Journal Article -
3
Birth characteristics and the risk of childhood leukaemias and lymphomas in New Zealand: a case-control study
Published in BMC blood disorders (14-09-2006)“…Some studies have found that lower parity and higher or lower social class (depending on the study) are associated with increased risks of childhood acute…”
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Journal Article -
4
The pharmaceutical market for obesity therapies
Published in Nature reviews. Drug discovery (01-09-2012)“…In the wake of the recent approvals of the first new obesity therapies in more than a decade, Wong and colleagues analyse their market prospects as well as the…”
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Journal Article -
5
Intrapleural tissue plasminogen activator and deoxyribonuclease therapy for pleural infection
Published in Journal of thoracic disease (01-06-2015)“…Pleural infection remains a global health burden associated with significant morbidity. Drainage of the infected pleural fluid is important but can often be…”
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Journal Article -
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Dose De-escalation of Intrapleural Tissue Plasminogen Activator Therapy for Pleural Infection. The Alteplase Dose Assessment for Pleural Infection Therapy Project
Published in Annals of the American Thoracic Society (01-06-2017)“…Intrapleural therapy with a combination of tissue plasminogen activator (tPA) 10 mg and DNase 5 mg administered twice daily has been shown in randomized and…”
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Journal Article -
7
An unusual cause of carotid sinus hypersensitivity/syndrome
Published in New Zealand medical journal (10-02-2012)“…Presents an unusual case of carotid sinus hypersensitivity (CSH) resulting from malignancy, representing a diagnostic and therapeutic challenge. Source:…”
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Journal Article -
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Modulation of the 5′-Deoxyribose-5-phosphate Lyase and DNA Synthesis Activities of Mammalian DNA Polymerase β by Apurinic/Apyrimidinic Endonuclease 1
Published in The Journal of biological chemistry (11-06-2004)“…The Ape1 protein initiates the repair of apurinic/apyrimidinic sites during mammalian base excision repair (BER) of DNA. Ape1 catalyzes hydrolysis of the…”
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Journal Article -
9
Modulation of the 5â²-Deoxyribose-5-phosphate Lyase and DNA Synthesis Activities of Mammalian DNA Polymerase β by Apurinic/Apyrimidinic Endonuclease 1
Published in The Journal of biological chemistry (11-06-2004)“…The Ape1 protein initiates the repair of apurinic/apyrimidinic sites during mammalian base excision repair (BER) of DNA. Ape1 catalyzes hydrolysis of the…”
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Journal Article -
10
Modulation of the 3′→5′-Exonuclease Activity of Human Apurinic Endonuclease (Ape1) by Its 5′-incised Abasic DNA Product
Published in The Journal of biological chemistry (19-09-2003)“…The major abasic endonuclease of human cells, Ape1 protein, is a multifunctional enzyme with critical roles in base excision repair (BER) of DNA. In addition…”
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Journal Article -
11
Covalent Trapping of Human DNA Polymerase β by the Oxidative DNA Lesion 2-Deoxyribonolactone
Published in The Journal of biological chemistry (08-03-2002)“…Oxidized abasic residues in DNA constitute a major class of radiation and oxidative damage. Free radical attack on the nucleotidyl C-1′ carbon yields…”
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Journal Article -
12
Observed smoking in cars: a method and differences by socioeconomic area
Published in Tobacco control (01-10-2006)“…Objectives: To establish a reproducible method to estimate he point prevalence of smoking and second-hand smoke (SHS) exposure in cars, and to compare this…”
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Journal Article -
13
Enhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatch
Published in Nucleic acids research (01-02-2001)“…Adenine-DNA glycosylase MutY of Escherichia coli catalyzes the cleavage of adenine when mismatched with 7,8-dihydro-8-oxoguanine (GO), an oxidatively damaged…”
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Journal Article -
14
Modulation of the 3â²â5â²-Exonuclease Activity of Human Apurinic Endonuclease (Ape1) by Its 5â²-incised Abasic DNA Product
Published in The Journal of biological chemistry (19-09-2003)“…The major abasic endonuclease of human cells, Ape1 protein, is a multifunctional enzyme with critical roles in base excision repair (BER) of DNA. In addition…”
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Observed smoking in cars: a method and differences by socioeconomic area: Table 1
Published in Tobacco control (01-10-2006)“…Objectives: To establish a reproducible method to estimate he point prevalence of smoking and second-hand smoke (SHS) exposure in cars, and to compare this…”
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Journal Article -
17
Coordination of mammalian base excision repair of DNA by AP endonuclease 1 and DNA polymerase beta
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Dissertation -
18
Coordination of mammalian base excision repair of DNA by AP endonuclease 1 and DNA polymerase beta
Published 01-01-2003“…The etiology of cancer involves the accumulation of mutations that stem from the persistence of unrepaired DNA damage. DNA is under constant attack by…”
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Dissertation -
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Covalent Trapping of Human DNA Polymerase β by the Oxidative DNA Lesion 2-Deoxyribonolactone
Published in The Journal of biological chemistry (08-03-2002)“…Oxidized abasic residues in DNA constitute a major class of radiation and oxidative damage. Free radical attack on the nucleotidyl C-1â² carbon yields…”
Get full text
Journal Article -
20
An unusual cause of carotid sinus hypersensitivity/syndrome
Published in The New Zealand medical journal (10-02-2012)Get full text
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