Search Results - "Donnelly, James C"

Repurposing Antimalarial Pyronaridine as a DNA Repair Inhibitor to Exploit the Full Potential of Gold-Nanoparticle-Mediated Radiation Response by Jackson, Nolan, Alhussan, Abdulaziz, Bromma, Kyle, Jay, David, Donnelly, James C, West, Frederick G, Lavasanifar, Afsaneh, Weinfeld, Michael, Beckham, Wayne, Chithrani, Devika B

“…Radiation therapy (RT) is frequently used to locally treat tumors. One of the major issues in RT is normal tissue toxicity; thus, it is necessary to limit dose…”
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Modulation of ERCC1-XPF Heterodimerization Inhibition via Structural Modification of Small Molecule Inhibitor Side-Chains by Weilbeer, Claudia, Jay, David, Donnelly, James C, Gentile, Francesco, Karimi-Busheri, Feridoun, Yang, Xiaoyan, Mani, Rajam S, Yu, Yaping, Elmenoufy, Ahmed H, Barakat, Khaled H, Tuszynski, Jack A, Weinfeld, Michael, West, Frederick G

“…Inhibition of DNA repair enzymes is an attractive target for increasing the efficacy of DNA damaging chemotherapies. The ERCC1-XPF heterodimer is a key…”
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Effect of multivitamins on plasma homocysteine and folate levels in patients on hemodialysis by House, A A, Donnelly, J G

“…Hyperhomocysteinemia is a risk factor for cardiovascular disease in patients on hemodialysis. Causes include genetic enzyme deficiencies, chronic renal…”
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