Search Results - "Donker, G.H"

Column chromatographic characterization of complex formation of pro-IGF-II isoforms with acid labile subunit and IGF-binding proteins associated with non-islet cell tumour induced hypoglycaemia by van Veggel, K.M, Huits, R.M.H.G, Donker, G.H, Lentjes, E.G.W.M, van Doorn, J

“…Abstract Objective and design Non-islet cell tumour induced hypoglycaemia (NICTH) is a paraneoplastic phenomenon that is associated with the formation of…”
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Is aromatase cytochrome P450 involved in the pathogenesis of endometrioid endometrial cancer? by Jongen, V H W M, Thijssen, J H H, Hollema, H, Donker, G H, Santema, J G, Van der Zee, A G J, Heineman, M J

“…Prospectively, the relationship between androgen levels in the utero-ovarian circulation, aromatase activity in endometrial and body fat tissue, and the…”
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Intratumoral levels of estrogens in breast cancer by Blankenstein, M.A, van de Ven, J, Maitimu-Smeele, I, Donker, G.H, de Jong, P.Chr, Daroszewski, J, Szymczak, J, Milewicz, A, Thijssen, J.H.H

“…Breast cancer tissue is an endocrine organ and particularly the estrogen biosynthetic properties of this tissue have been well studied. The concentration of…”
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Effect of tibolone (Org OD14) and its metabolites on aromatase and estrone sulfatase activity in human breast adipose stromal cells and in MCF-7 and T47D breast cancer cells by van de Ven, J, Donker, G.H, Sprong, M, Blankenstein, M.A, Thijssen, J.H.H

“…Tibolone (Org OD14) is a synthetic steroid used for post-menopausal hormone replacement therapy (HRT). Since HRT might increase breast cancer risk, it is…”
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Progesterone receptor isoform expression in human meningiomas by Verheijen, F.M, Sprong, M, Jacobs, H.M, Donker, G.H, Amelink, G.J, Thijssen, J.H.H, Blankenstein, M.A

“…The majority of meningiomas express the progesterone receptor (PR), and therefore meningiomas are considered to be progesterone-responsive. In addition, an…”
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Functional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissue by Koehorst, S G, Cox, J J, Donker, G H, Lopes da Silva, S, Burbach, J P, Thijssen, J H, Blankenstein, M A

“…An alternatively spliced mRNA coding for a variant estrogen receptor (ER) missing exon 4 (ERdelta4) was detected in the breast tumor cell line MCF7 and…”
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On the significance of in situ production of oestrogens in human breast cancer tissue by Blankenstein, M A, Maitimu-Smeele, I, Donker, G H, Daroszewski, J, Milewicz, A, Thijssen, J H

“…We have previously shown that human breast cancer is autonomous in the regulation of its intra-tissue oestradiol concentration. Breast fatty tissue does not…”
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Endogenous steroid hormones and local aromatase activity in the breast by Thijssen, J H, Blankenstein, M A, Donker, G H, Daroszewski, J

“…To test the hypothesis of an increased activity of the enzyme aromatase in adipose tissue from affected when compared with non-affected quadrants of patients…”
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Oestrogen receptor independent expression of progestin receptors in human meningioma—a review by Blankenstein, M.A., Koehorst, S.G.A., van der Kallen, C.J.H., Jacobs, H.M., van Spriel, A.B., Donker, G.H., van't Verlaat, J.W., Blaauw, G., Thijssen, J.H.H.

“…Human meningiomas are rich in progestin receptors (PR), which are expressed in this tissue in an oestrogen independent fashion. In the search for an…”
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Tissue androgens and the endocrine autonomy of breast cancer by Blankenstein, M A, Maitimu-Smeele, I, Donker, G H, Daroszewski, J, Milewicz, A, Thijssen, J H

“…To evaluate whether a tumour-directed gradient in androgen levels in fatty tissue can account for the maintenance of intra-tissue oestradiol levels,…”
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The excretion of metabolites of testosterone and of estradiol in male patients with chronic renal failure by van Kammen, E, Thijssen, J H, Donker, G H, Schwarz, F

“…Intravenous infusions of 14C-testosterone (Te) either alone or in combination with 3H-estradiol (E2) were given to five normal male subjects, twelve male…”
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Uptake and metabolism of oestriol in human target tissues by Thijssen, J H, Wiegerninck, M A, Donker, G H, Poortman, J

“…The uptake, metabolism and subcellular distribution of oestradiol and oestriol in endometrial, myometrial and vaginal tissue of postmenopausal women under…”
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The influence of nandrolone decanoate (Deca-durabolin) on the peripheral conversion of androstenedione to oestrone by Andriesse, R, Thussen, J H, Donker, G H

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Oestrogen concentrations in plasma, endometrium, myometrium and vagina of postmenopausal women, and effects of vaginal oestriol (E3) and oestradiol (E2) applications by van Haaften, M, Donker, G H, Haspels, A A, Thijssen, J H

“…Oestradiol (E2), oestriol (E3) and oestrone (E1) levels were measured in plasma and endometrium, myometrium and vagina of 29 postmenopausal women who underwent…”
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Effects of oestriol: preliminary results on receptor kinetics in target tissues of postmenopausal women by van Haaften, M, Poortman, J, Donker, G H, Wiegerinck, M A, Haspels, A A, Thijssen, J H

“…This in vivo investigation was done to study the effects of intravaginal oestriol (E3) administration on endometrial, myometrial and vaginal tissue of normal…”
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