Search Results - "Dong, Zhengqi"

TPGS nanoparticles co-loaded with ABT-737 and R848 for breast cancer therapy by Lang, Xiaoxue, Wang, Xiangtao, Han, Meihua, Guo, Yifei, Dong, Zhengqi

“…The development of new effective drugs to treat breast cancer remains a huge challenge. ABT-737 can inhibit Bcl-2 proteins to promote apoptosis. Resiquimod…”
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Polypeptides-Based Nanocarriers in Tumor Therapy by You, Juhua, Guo, Yifei, Dong, Zhengqi

“…Cancer remains a worldwide problem, and new treatment strategies are being actively developed. Peptides have the characteristics of good biocompatibility,…”
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Effects of different conformations of polylysine on the anti-tumor efficacy of methotrexate nanoparticles by Yu, Bo, Lang, Xiaoxue, Wang, Xiangtao, Ding, Lijuan, Han, Meihua, Guo, Yifei, Dong, Zhengqi

“…Drug delivery systems require that carrier materials have good biocompatibility, degradability, and constructability. Poly(amino acids), a substance with a…”
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Contrasting dorsal caudate functional connectivity patterns between frontal and temporal cortex with BMI increase: link to cognitive flexibility by Zhao, Jizheng, Manza, Peter, Gu, Jun, Song, Huaibo, Zhuang, Puning, Shi, Fulei, Dong, Zhengqi, Lu, Cheng, Wang, Gene-Jack, He, Dongjian

“…Background Obesity is associated with brain intrinsic functional reorganization. However, little is known about the BMI-related interhemispheric functional…”
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Plant Polyphenols Attenuate DSS-induced Ulcerative Colitis in Mice via Antioxidation, Anti-inflammation and Microbiota Regulation by Chen, Huan, Li, Ying, Wang, Jinrui, Zheng, Tingting, Wu, Chenyang, Cui, Mengyao, Feng, Yifan, Ye, Hanyi, Dong, Zhengqi, Dang, Yunjie

“…The pathogenesis of ulcerative colitis (UC) is associated with inflammation, oxidative stress, and gut microbiota imbalance. Although most researchers have…”
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Preparation of Naringenin Nanosuspension and Its Antitussive and Expectorant Effects by Dong, Zhengqi, Wang, Rui, Wang, Mingyue, Meng, Zheng, Wang, Xiaotong, Han, Meihua, Guo, Yifei, Wang, Xiangtao

“…Naringenin (NRG) is a natural flavonoid compound abundantly present in citrus fruits and has the potential to treat respiratory disorders. However, the…”
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Efficacy and Molecular Mechanism of Quercetin on Constipation Induced by Berberine via Regulating Gut Microbiota by Cui, Mengyao, Li, Ying, Zheng, Tingting, Chen, Huan, Wang, Jinrui, Feng, Yifan, Ye, Hanyi, Dong, Zhengqi, Li, Geng

“…Berberine (BBR) is used to treat cancer, inflammatory conditions, and so on. But the side effects of BBR causing constipation should not be ignored. In…”
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Effect and Mechanism of Pharmaceutical Excipients on Berberine to Alleviate Ulcerative Colitis via Regulating Gut Microbiota by Wu, Chenyang, Zheng, Tingting, Chen, Huan, Zou, Peizhi, Zhang, Mengxue, Wang, Jinrui, Li, Nan, Zhang, Yun, Li, Ying, Dong, Zhengqi

“…Background: Various potential effect of drugs on alleviating diseases by regulating intestinal microbiome as well as the pharmaceutical excipients on gut…”
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Effects of polyamidoamine (PAMAM) dendrimers on the nasal absorption of poorly absorbable drugs in rats by Dong, Zhengqi, Katsumi, Hidemasa, Sakane, Toshiyasu, Yamamoto, Akira

“…The absorption enhancing effects of polyamidoamine (PAMAM) dendrimers with various concentrations and generations on the nasal absorption of fluorescein…”
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Advances in natural compound-based nanomedicine and the interaction with gut microbiota in ulcerative colitis therapy by Zhang, Jinlan, Sun, Shuhui, Chen, Huan, Feng, Yifan, Li, Ying, Dong, Zhengqi

“…Ulcerative colitis (UC) is a chronic inflammatory bowel disorder of the large intestine. Previous studies have indicated that the gut microbiota plays an…”
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Optimization of Naringenin Nanoparticles to Improve the Antitussive Effects on Post-Infectious Cough by Dong, Zhengqi, Wang, Xiangtao, Wang, Mingyue, Wang, Rui, Meng, Zheng, Wang, Xiaotong, Yu, Bo, Han, Meihua, Guo, Yifei

“…Naringenin (NRG) is a natural compound with several biological activities; however, its bioavailability is limited owing to poor aqueous solubility. In this…”
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Combined Photothermal Therapy and Lycium barbarum Polysaccharide for Topical Administration to Improve the Efficacy of Doxorubicin in the Treatment of Breast Cancer by Sun, Lina, Zuo, Cuiling, Liu, Xinxin, Guo, Yifei, Wang, Xiangtao, Dong, Zhengqi, Han, Meihua

“…In order to improve the efficacy of doxorubicin in the treatment of breast cancer, we constructed a drug delivery system combined with local administration of…”
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Co-assembled nanocomplexes comprising epigallocatechin gallate and berberine for enhanced antibacterial activity against multidrug resistant Staphylococcus aureus by Zheng, Tingting, Cui, Mengyao, Chen, Huan, Wang, Jinrui, Ye, Hanyi, Zhang, Qianqian, Sun, Shuhui, Feng, Yifan, Zhang, Yinghua, Liu, Wei, Chen, Renping, Li, Ying, Dong, Zhengqi

“…Berberine (BBR), a major alkaloid in Coptis chinensis, and (-)-epigallocatechin-3-gallate (EGCG), a major catechin in green tea, are two common phytochemicals…”
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Self-adjuvant Astragalus polysaccharide-based nanovaccines for enhanced tumor immunotherapy: a novel delivery system candidate for tumor vaccines by Li, Nan, Zhang, Yun, Han, Miaomiao, Liu, Tian, Wu, Jinjia, Xiong, Yingxia, Fan, Yikai, Ye, Fan, Jin, Bing, Zhang, Yinghua, Sun, Guibo, Sun, Xiaobo, Dong, Zhengqi

“…The study of tumor nanovaccines (NVs) has gained interest because they specifically recognize and eliminate tumor cells. However, the poor recognition and…”
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Rhubarb polysaccharide and berberine co-assembled nanoparticles ameliorate ulcerative colitis by regulating the intestinal flora by Feng, Yifan, Wu, Chenyang, Chen, Huan, Zheng, Tingting, Ye, Hanyi, Wang, Jinrui, Zhang, Yinghua, Gao, Jia, Li, Ying, Dong, Zhengqi

“…Inflammatory bowel disease (IBD) affects about 7 million people globally, which is a chronic inflammatory condition of the gastrointestinal tract caused by gut…”
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Anti-HIV Potential of Beesioside I Derivatives as Maturation Inhibitors: Synthesis, 3D-QSAR, Molecular Docking and Molecular Dynamics Simulations by Zhao, Zixuan, Ma, Yinghong, Li, Xiangyuan, Morris-Natschke, Susan L, Sun, Zhaocui, Sun, Zhonghao, Ma, Guoxu, Dong, Zhengqi, Zhao, Xiaohong, Yang, Meihua, Xu, Xudong, Lee, Kuohsiung, Wu, Haifeng, Chen, Chinho

“…HIV-1 maturation is the final step in the retroviral lifecycle that is regulated by the proteolytic cleavage of the Gag precursor protein. As a first-in-class…”
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Hydrophilic Poly(glutamic acid)-Based Nanodrug Delivery System: Structural Influence and Antitumor Efficacy by Guo, Yifei, Shen, Yiping, Yu, Bo, Ding, Lijuan, Meng, Zheng, Wang, Xiaotong, Han, Meihua, Dong, Zhengqi, Wang, Xiangtao

“…Poly(amino acids) have advanced characteristics, including unique secondary structure, enzyme degradability, good biocompatibility, and stimuli responsibility,…”
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Widely targeted metabolomic analysis reveals effects of yellowing process time on the flavor of vine tea (Ampelopsis grossedentata) by Qi, Shunyao, Zeng, Tiexin, Wu, Peiling, Sun, Le, Dong, Zhengqi, Xu, Lijia, Xiao, Peigen

“…The bitter and astringent taste and miscellaneous smell of vine tea prevent its further development. In this study, we used a processing technology that mimics…”
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Fabrication of Co-Assembly from Berberine and Tannic Acid for Multidrug-Resistant Bacteria Infection Treatment by Zheng, Tingting, Chen, Huan, Wu, Chenyang, Wang, Jinrui, Cui, Mengyao, Ye, Hanyi, Feng, Yifan, Li, Ying, Dong, Zhengqi

“…Long-term antibiotic use induces drug resistance in bacteria. This has given rise to the challenge of refractory infections, which have become a global health…”
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The Effect of Absorption-Enhancement and the Mechanism of the PAMAM Dendrimer on Poorly Absorbable Drugs by Lu, Juan, Li, Nannan, Gao, Yaochun, Li, Nan, Guo, Yifei, Liu, Haitao, Chen, Xi, Zhu, Chunyan, Dong, Zhengqi, Yamamoto, Akira

“…The polyamidoamine (PAMAM) dendrimer is a highly efficient absorption promoter. In the present study, we studied the absorption-enhancing effects and the…”
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