Search Results - "Dong, Yuanlin"
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Sevoflurane induces cognitive impairment in young mice via autophagy
Published in PloS one (20-05-2019)“…Anesthesia may induce neurotoxicity and neurocognitive impairment in young mice. However, the underlying mechanism remains largely to be determined. Meanwhile,…”
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2
Tau Contributes to Sevoflurane-induced Neurocognitive Impairment in Neonatal Mice
Published in Anesthesiology (Philadelphia) (01-09-2020)“…BACKGROUND:Sevoflurane anesthesia induces Tau phosphorylation and cognitive impairment in neonatal but not in adult mice. This study tested the hypothesis that…”
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3
Impact of adrenomedullin on mitochondrial respiratory capacity in human adipocyte
Published in Scientific reports (13-06-2023)“…Mitochondrial function in adipocyte is an important aspect in maintaining metabolic homeostasis. Our previous observation showed that circulating levels of…”
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4
Sevoflurane Induces Tau Phosphorylation and Glycogen Synthase Kinase 3β Activation in Young Mice
Published in Anesthesiology (Philadelphia) (01-09-2014)“…Children with multiple exposures to anesthesia and surgery may have an increased risk of developing cognitive impairment. Sevoflurane is a commonly used…”
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5
Selective Anesthesia-induced Neuroinflammation in Developing Mouse Brain and Cognitive Impairment
Published in Anesthesiology (Philadelphia) (01-03-2013)“…: Recent population studies have suggested that children with multiple exposures to anesthesia and surgery at an early age are at an increased risk of…”
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6
Anesthesia and Surgery Impair Blood-Brain Barrier and Cognitive Function in Mice
Published in Frontiers in immunology (09-08-2017)“…Blood-brain barrier (BBB) dysfunction, e.g., increase in BBB permeability, has been reported to contribute to cognitive impairment. However, the effects of…”
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Anesthetic Sevoflurane Causes Neurotoxicity Differently in Neonatal Naïve and Alzheimer Disease Transgenic Mice
Published in Anesthesiology (Philadelphia) (01-06-2010)“…Recent studies have suggested that children undergoing surgery under anesthesia could be at an increased risk for the development of learning disabilities, but…”
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8
Battery of behavioral tests in mice to study postoperative delirium
Published in Scientific reports (20-07-2016)“…Postoperative delirium is associated with increased morbidity, mortality and cost. However, its neuropathogenesis remains largely unknown, partially owing to…”
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9
Anesthetic Isoflurane Induces DNA Damage Through Oxidative Stress and p53 Pathway
Published in Molecular neurobiology (01-07-2017)“…DNA damage is associated with aging and neurological disorders, including Alzheimer’s disease. Isoflurane is a commonly used anesthetic. It remains largely…”
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10
Sevoflurane Induces a Cyclophilin D-Dependent Decrease of Neural Progenitor Cells Migration
Published in International journal of molecular sciences (01-04-2023)“…Clinical studies have suggested that repeated exposure to anesthesia and surgery at a young age may increase the risk of cognitive impairment. Our previous…”
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11
Lipid dysfunction and adrenomedullin expression in omental versus subcutaneous adipose tissues in diabetic pregnancies
Published in PloS one (07-04-2022)“…Gestational diabetes mellitus (GDM) is one of the most common complications of pregnancy but the underlying mechanism remains obscure. The aims of this study…”
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12
Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory
Published in Annals of neurology (01-05-2012)“…Objective: There are approximately 8.5 million Alzheimer disease (AD) patients who need anesthesia and surgery care every year. The inhalation anesthetic…”
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13
Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and Aβ generation
Published in PloS one (20-06-2012)“…Anesthetic isoflurane has been shown to promote Alzheimer's disease (AD) neuropathogenesis by inducing caspase activation and accumulation of β-amyloid (Aβ)…”
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14
EEG-based emotion recognition using graph convolutional neural network with dual attention mechanism
Published in Frontiers in computational neuroscience (19-07-2024)“…EEG-based emotion recognition is becoming crucial in brain-computer interfaces (BCI). Currently, most researches focus on improving accuracy, while neglecting…”
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15
The Mitochondrial Pathway of Anesthetic Isoflurane-induced Apoptosis
Published in The Journal of biological chemistry (05-02-2010)“…The common inhalation anesthetic isoflurane has been shown to induce apoptosis, which then leads to accumulation of β-amyloid protein, the hallmark feature of…”
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The anesthetic sevoflurane induces tau trafficking from neurons to microglia
Published in Communications biology (12-05-2021)“…Accumulation and spread of tau in Alzheimer’s disease and other tauopathies occur in a prion-like manner. However, the mechanisms and downstream consequences…”
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17
Sleep disturbance induces neuroinflammation and impairment of learning and memory
Published in Neurobiology of disease (01-12-2012)“…Abstract Hospitalized patients can develop cognitive function decline, the mechanisms of which remain largely to be determined. Sleep disturbance often occurs…”
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Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans
Published in Scientific reports (14-07-2021)“…Anesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in…”
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19
Sevoflurane induces neuronal activation and behavioral hyperactivity in young mice
Published in Scientific reports (08-07-2020)“…Sevoflurane, a commonly used anesthetic, may cause agitation in patients. However, the mechanism underlying this clinical observation remains largely unknown…”
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20
Adrenomedullin and its receptors are expressed in mouse pancreatic β-cells and suppresses insulin synthesis and secretion
Published in PloS one (24-03-2022)“…Gestational diabetes mellitus (GDM) is associated with defective pancreatic β-cell adaptation in pregnancy, but the underlying mechanism remains obscure. Our…”
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