Search Results - "Dong, Xiaoxv"
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Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics
Published in Phytotherapy research (01-08-2016)“…Emodin is a natural anthraquinone derivative that occurs in many widely used Chinese medicinal herbs, such as Rheum palmatum, Polygonum cuspidatum and…”
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Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology
Published in BioMed research international (01-01-2017)“…Radix Bupleuri (Chaihu) has been used as a traditional medicine for more than 2000 years in China, Japan, Korea, and other Asian countries. Phytochemical…”
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Metal Organic Frameworks as Drug Targeting Delivery Vehicles in the Treatment of Cancer
Published in Pharmaceutics (05-03-2020)“…In recent years, metal organic frameworks (MOFs) have been widely developed as vehicles for the effective delivery of drugs to tumor tissues. Due to the high…”
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In Vitro Toxicity Study of a Porous Iron(III) Metal‒Organic Framework
Published in Molecules (Basel, Switzerland) (28-03-2019)“…A MIL series metal‒organic framework (MOF), MIL-100(Fe), was successfully synthesized at the nanoscale and fully characterized by TEM, TGA, XRD, FTIR, DLS, and…”
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5
Itraconazole exerts anti-liver cancer potential through the Wnt, PI3K/AKT/mTOR, and ROS pathways
Published in Biomedicine & pharmacotherapy (01-11-2020)“…[Display omitted] Hepatocellular carcinoma (HCC) is one of the most common cancers with the highest morbidity and mortality. It is necessary to develop new…”
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Investigation of Metal-Organic Framework-5 (MOF-5) as an Antitumor Drug Oridonin Sustained Release Carrier
Published in Molecules (Basel, Switzerland) (16-09-2019)“…Oridonin (ORI) is a natural active ingredient with strong anticancer activity. But its clinical use is restricted due to its poor water solubility, short…”
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Biocompatible Fe-Based Micropore Metal-Organic Frameworks as Sustained-Release Anticancer Drug Carriers
Published in Molecules (Basel, Switzerland) (28-09-2018)“…Sustained-release preparation is a hot spot in antitumor drug research, where the first task is to select suitable drug carriers. Research has revealed that…”
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Induction of Apoptosis in HepaRG Cell Line by Aloe-Emodin through Generation of Reactive Oxygen Species and the Mitochondrial Pathway
Published in Cellular physiology and biochemistry (01-01-2017)“…Background/Aims: Aloe-emodin (1,8-dihydroxy-3-hydroxymethyl-anthraquinone), an anthraquinone active compounds, is isolated from some traditional medicinal…”
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A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine
Published in Frontiers in pharmacology (16-09-2020)“…Matrine (MT) is a naturally occurring alkaloid and an bioactive component of Chinese herbs, such as and Radix . Emerging evidence suggests that MT possesses…”
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Inhibitory effects of Paris saponin I, II, Ⅵ and Ⅶ on HUVEC cells through regulation of VEGFR2, PI3K/AKT/mTOR, Src/eNOS, PLCγ/ERK/MERK, and JAK2-STAT3 pathways
Published in Biomedicine & pharmacotherapy (01-11-2020)“…[Display omitted] •Paris saponins I, II, Ⅵ and Ⅶ are the major bioactive compounds in Rhizoma Paris.•HUVEC cells was used for the first time to explore the…”
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Rhein Induces Cell Death in HepaRG Cells through Cell Cycle Arrest and Apoptotic Pathway
Published in International journal of molecular sciences (02-04-2018)“…Rhein, a naturally occurring active anthraquinone found abundantly in various medicinal and nutritional herbs, possesses a wide spectrum of pharmacological…”
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12
Quality evaluation of Lycium barbarum (wolfberry) from different regions in China based on polysaccharide structure, yield and bioactivities
Published in Chinese medicine (08-11-2019)“…(wolfberry) has been widely cultivated in China, particularly in northwest regions. However, the fruit size and taste of from different habitats are quite…”
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Ginsenoside Rb1 Attenuates Triptolide-Induced Cytotoxicity in HL-7702 Cells via the Activation of Keap1/Nrf2/ARE Pathway
Published in Frontiers in pharmacology (03-01-2022)“…Triptolide (TP) is the major bioactive compound extracted from Hook F. It exerts anti-inflammatory, antirheumatic, antineoplastic, and neuroprotective effects…”
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A Novel Gel-Forming Solution Based on PEG-DSPE/Solutol HS 15 Mixed Micelles and Gellan Gum for Ophthalmic Delivery of Curcumin
Published in Molecules (Basel, Switzerland) (24-12-2019)“…Curcumin (Cur) is a naturally hydrophobic polyphenol with potential pharmacological properties. However, the poor aqueous solubility and low bioavailability of…”
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Polygonum multiflorum -Induced Liver Injury: Clinical Characteristics, Risk Factors, Material Basis, Action Mechanism and Current Challenges
Published in Frontiers in pharmacology (13-12-2019)“…Thunb. (PM), called in China, is a popular Chinese medicine in clinical practice. Several clinical studies have been conducted to evaluate the traditional…”
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Preparation, Characterization, and In Vitro Release of Curcumin-Loaded IRMOF-10 Nanoparticles and Investigation of Their Pro-Apoptotic Effects on Human Hepatoma HepG2 Cells
Published in Molecules (Basel, Switzerland) (20-06-2022)“…Curcumin (CUR) has a bright future in the treatment of cancer as a natural active ingredient with great potential. However, curcumin has a low solubility,…”
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Pharmacology, toxicity and pharmacokinetics of acetylshikonin: a review
Published in Pharmaceutical biology (01-01-2020)“…Acetylshikonin, a naphthoquinone derivative, is mainly extracted from some species of the family Boraginaceae, such as Lithospermum erythrorhizon Sieb. et…”
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Co-delivery of polyphyllin II and IR780 PLGA nanoparticles induced pyroptosis combined with photothermal to enhance hepatocellular carcinoma immunotherapy
Published in Journal of nanobiotechnology (21-10-2024)“…The clinical efficacy of immunotherapy for hepatocellular carcinoma (HCC) is significantly limited by the low immunogenicity of the tumor. Recent studies have…”
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Underlying mechanisms of apoptosis in HepG2 cells induced by polyphyllin I through Fas death and mitochondrial pathways
Published in Toxicology mechanisms and methods (23-07-2020)“…Aims: Polyphyllin I, a steroidal saponin in Rhizoma paridis, which possess broad application prospects in cancer prevention and treatment. The purpose of this…”
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Study on the potential effective ingredients of Xiaosheng prescription for dry eye disease
Published in Biomedicine & pharmacotherapy (01-07-2020)“…[Display omitted] •Xiaosheng prescription comes from clinic with definite curative effect.•Efficacy data combined with component data to reduce experimental…”
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