Search Results - "Dong, Mengjin"

DeepAtrophy: Teaching a neural network to detect progressive changes in longitudinal MRI of the hippocampal region in Alzheimer's disease by Dong, Mengjin, Xie, Long, Das, Sandhitsu R., Wang, Jiancong, Wisse, Laura E.M., deFlores, Robin, Wolk, David A., Yushkevich, Paul A.

“…Measures of change in hippocampal volume derived from longitudinal MRI are a well-studied biomarker of disease progression in Alzheimer's disease (AD) and are…”
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Detection and Localization of Progressive Changes in Longitudinal MRI of the Hippocampal Region in Alzheimer’s Disease With Deep Learning by Dong, Mengjin

“…The human hippocampal formation is a very small anatomical region in the brain, yet it is essential in the declarative memory system, which encompasses stored…”
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Construction of cinnamic acids derived β-cyclodextrins and their emodin-based inclusions with enhanced water solubility, excellent antioxidant and antibacterial activities by Zhang, Jing, Li, Nini, Zhang, Dongmei, Dong, Mengjin, Wang, Changhao, Chen, Yashao

“…[Display omitted] β-Cyclodextrin (β-CD) is a natural macromolecule which has been regarded as a promising biomaterial and drug carrier. However, the poor water…”
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Deep Learning Registration with Scan‐temporal Consistency May Improve Detection of Alzheimer’s Disease Progression by Dong, Mengjin, Xie, Long, Wang, Jiancong, Das, Sandhitsu R., Wolk, David A., Yushkevich, Paul A.

“…Background Structural changes in Alzheimer’s disease (AD) can be detected as atrophy in the medial temporal lobe (MTL), which is normally studied by applying…”
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Comparison of Focal Hippocampal T2‐Weighted MRI and Whole‐Brain T1‐Weighted MRI for Detection of Longitudinal Atrophy Using Deep Learning‐Based and Conventional Approaches by Dong, Mengjin, Xie, Long, Wisse, Laura, de Flores, Robin, Wang, Jiancong, Das, Sandhitsu R., Wolk, David A., Yushkevich, Paul A.

“…Background Longitudinal measurement of medial temporal lobe (MTL) atrophy is shown to be effective in measuring Alzheimer’s disease (AD) progression and has…”
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Longitudinal atrophy in early Braak regions in preclinical Alzheimer's disease by Xie, Long, Wisse, Laura E. M., Das, Sandhitsu R., Vergnet, Nicolas, Dong, Mengjin, Ittyerah, Ranjit, Flores, Robin, Yushkevich, Paul A., Wolk, David A.

“…A major focus of Alzheimer's disease (AD) research has been finding sensitive outcome measures to disease progression in preclinical AD, as intervention…”
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Mapping Medial Temporal Lobe Longitudinal Change in Preclinical Alzheimer’s Disease by Yushkevich, Paul A., Xie, Long, Wisse, Laura EM, Dong, Mengjin, Ravikumar, Sadhana, Ittyerah, Ranjit, de Flores, Robin, Das, Sandhitsu R., Wolk, David A.

“…Background The medial temporal lobe (MTL) is a site of early tau pathology and neurodegeneration in AD. In recent work [1], we reported that rates of change in…”
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Mapping Medial Temporal Lobe Longitudinal Change in Preclinical Alzheimer’s Disease by Yushkevich, Paul A., Xie, Long, Wisse, Laura EM, Dong, Mengjin, Ravikumar, Sadhana, Ittyerah, Ranjit, de Flores, Robin, Das, Sandhitsu R., Wolk, David A.

“…Background The medial temporal lobe (MTL) is a site of early tau pathology and neurodegeneration in AD. In recent work [1], we reported that rates of change in…”
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Sensitive biomarkers to Alzheimer's disease progression in longitudinal MRI from deep learning by Dong, Mengjin, Xie, Long, Wang, Jiancong, Das, Sandhitsu R, Wolk, David A, Yushkevich, Paul

“…Background In clinical trials of disease‐modifying treatments of Alzheimer’s disease (AD), the measure of hippocampus volume change from longitudinal MRI is a…”
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Detecting biological changes in longitudinal MRI scans of Alzheimer’s disease patients in the hippocampus region with deep learning by Dong, Mengjin, Xie, Long, Das, Sandhitsu R., Wolk, David A., Yushkevich, Paul A.

“…Background Alzheimer's Disease (AD) is characterized by gradual loss of gray matter, particularly in the medial temporal lobe (MTL) and hippocampus…”
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Sensitive biomarkers to Alzheimer's disease progression in longitudinal MRI from deep learning: Developing topics by Dong, Mengjin, Xie, Long, Wang, Jiancong, Das, Sandhitsu R, Wolk, David A, Yushkevich, Paul

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Detecting biological changes in longitudinal MRI scans of Alzheimer’s disease patients in the hippocampus region with deep learning: Neuroimaging / Optimal neuroimaging measures for tracking disease progression by Dong, Mengjin, Xie, Long, Das, Sandhitsu R., Wolk, David A., Yushkevich, Paul A.

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Regional deep atrophy: Using temporal information to automatically identify regions associated with Alzheimer’s disease progression from longitudinal MRI by Dong, Mengjin, Xie, Long, Das, Sandhitsu R., Wang, Jiancong, Wisse, Laura E.M., deFlores, Robin, Wolk, David A., Yushkevich, Paul A.

“…Longitudinal assessment of brain atrophy, particularly in the hippocampus, is a well-studied biomarker for neurodegenerative diseases, such as Alzheimer’s…”
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Association of quantitative histopathology measurements with antemortem medial temporal lobe cortical thickness in the Alzheimer’s disease continuum by Denning, Amanda E., Ittyerah, Ranjit, Levorse, Lisa M., Sadeghpour, Niyousha, Athalye, Chinmayee, Chung, Eunice, Ravikumar, Sadhana, Dong, Mengjin, Duong, Michael Tran, Li, Yue, Ilesanmi, Ademola, Sreepada, Lasya P., Sabatini, Philip, Lowe, MaKayla, Bahena, Alejandra, Zablah, Jamila, Spencer, Barbara E., Watanabe, Ryohei, Kim, Boram, Sørensen, Maja Højvang, Khandelwal, Pulkit, Brown, Christopher, Hrybouski, Stanislau, Xie, Sharon X., de Flores, Robin, Robinson, John L., Schuck, Theresa, Ohm, Daniel T., Arezoumandan, Sanaz, Porta, Sílvia, Detre, John A., Insausti, Ricardo, Wisse, Laura E. M., Das, Sandhitsu R., Irwin, David J., Lee, Edward B., Wolk, David A., Yushkevich, Paul A.

“…The medial temporal lobe (MTL) is a hotspot for neuropathology, and measurements of MTL atrophy are often used as a biomarker for cognitive decline associated…”
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Polyelectrolytes fabrication on magnesium alloy surface by layer-by-layer assembly technique with antiplatelet adhesion and antibacterial activities by Peng, Mengke, Zhang, Xiaodan, Xiao, Xiao, Dong, Mengjin, Zhao, Guowei, Liu, Peng, Chen, Yashao, Wang, Changhao

“…Magnesium alloy (MgA) was widely used in biomedical field owing to its good biocompatibility and degradability. The surface of MgA was usually modified to…”
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Application of histopathologically derived 3D tau burden map as in‐vivo region of interest for biomarker analysis by Das, Sandhitsu R., Xie, Long, de Flores, Robin, Munoz, Monica, de Onzono Martin, Maria Mercedes Iniguez, Ittyerah, Ranjit, Lim, Sydney A, Ravikumar, Sadhana, Lavery, Madigan, Pickup, Stephen R, Liu, Weixia, Wang, Jiancong, Hung, Ling Yu, Lasserve, Jade, Vergnet, Nicolas, Dong, Mengjin, Cui, Salena, McCollum, Lauren, Robinson, John, Schuck, Theresa, Grossman, Murray, Tisdall, Dylan M, Prabhakaran, Karthik, Mizsei, Gabor, Artacho‐Perula, Emilio, del Mar Arroyo Jimenez, Maria, del Pilar Marcos Rabal, Maria, Romero, Francisco Javier Molina, Sanchez, Sandra Cebada, González, José Carlos Delgado, de la Rosa Prieto, Carlos, Parada, Marta Córcoles, Lee, Eddie B, Trojanowski, John Q, Ohm, Daniel T, Nasrallah, Ilya M., Kelley, Melissa, Lane, Jacqueline, Dicalogero, Michael, Wisse, Laura, Irwin, David J., Insausti, Ricardo, Yushkevich, Paul, Wolk, David A.

“…Background Quantitative three‐dimensional maps of tau neurofibrillary tangles (NFT) burden derived from dense serial histology have potential application for…”
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3D Mapping of TAU Neurofibrillary Tangle Pathology in the Human Medial Temporal Lobe by Yushkevich, Paul A., de Onzono Martin, Maria Mercedes Iniguez, Ittyerah, Ranjit, Lim, Sydney, Lavery, Madigan, Wang, Jiancong, Hung, Ling Yu, Vergnet, Nicolas, Ravikumar, Sadhana, Xie, Long, Dong, Mengjin, DeFlores, Robin, Cui, Salena, McCollum, Lauren, Ohm, Daniel T., Robinson, John L., Schuck, Theresa, Grossman, Murray, Tisdall, M. Dylan, Prabhakaran, Karthik, Mizsei, Gabor, Das, Sandhitsu R., Artacho-Perula, Emilio, del Mar Arroyo Jimenez, Maria, Lopez, Monica Munoz, Rabal, Maria Pilar Marcos, Romero, Francisco Javier Molina, Lee, Edward B., Trojanowski, John Q., Wisse, Laura E.M., Wolk, David A., Irwin, David J., Insausti, Ricardo

“…Tau protein neurofibrillary tangles (NFT) are linked to neuronal and synaptic loss and cognitive decline in Alzheimer's disease (AD) and related dementias. In…”
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Neural Ordinary Differential Equation based Sequential Image Registration for Dynamic Characterization by Wu, Yifan, Dong, Mengjin, Jena, Rohit, Qin, Chen, Gee, James C

“…Deformable image registration (DIR) is crucial in medical image analysis, enabling the exploration of biological dynamics such as organ motions and…”
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Regional Deep Atrophy: a Self-Supervised Learning Method to Automatically Identify Regions Associated With Alzheimer's Disease Progression From Longitudinal MRI by Dong, Mengjin, Xie, Long, Das, Sandhitsu R, Wang, Jiancong, Wisse, Laura E. M, deFlores, Robin, Wolk, David A, Yushkevich, Paul A

“…Longitudinal assessment of brain atrophy, particularly in the hippocampus, is a well-studied biomarker for neurodegenerative diseases, such as Alzheimer's…”
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DeepAtrophy: Teaching a Neural Network to Differentiate Progressive Changes from Noise on Longitudinal MRI in Alzheimer's Disease by Dong, Mengjin, Xie, Long, Das, Sandhitsu R, Wang, Jiancong, Wisse, Laura E. M, deFlores, Robin, Wolk, David A, Yushkevich, Paul

“…Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD)…”
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