Search Results - "Dong, J. T."

Krüppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1 by Zheng, H -Q, Zhou, Z, Huang, J, Chaudhury, L, Dong, J -T, Chen, C

“…The Krüppel-like factor 5 (KLF5) is a zinc-finger transcription factor promoting cell proliferation, cell-cycle progression and survival. A high expression…”
Get full text

Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer by CHEN, C, SUN, X, ATFI, A, DONG, J.-T, GUO, P, DONG, X.-Y, SETHI, P, ZHOU, W, ZHOU, Z, PETROS, J, FRIERSON, H. F, VESSELLA, R. L

“…The gene for E3 ubiquitin ligase WWP1 is located at 8q21, a region frequently amplified in human cancers, including prostate cancer. Recent studies have shown…”
Get full text

Fibulin-5 protects the extracellular matrix of chondrocytes by inhibiting the Wnt/β-catenin signaling pathway and relieves osteoarthritis by Gao, J-B, Lin, L, Men, X-Q, Zhao, J-B, Zhang, M-H, Jin, L-P, Gao, S-J, Zhao, S-Q, Dong, J-T

“…Osteoarthritis (OA) is a common disease in the elderly and seriously affects the quality of life of patients. The purpose of this study was to explore the…”
Get more information

Detecting seismic IR anomalies in bi-angular Advanced Along-Track Scanning Radiometer data by Xiong, P, Gu, X. F, Bi, Y. X, Shen, X. H, Meng, Q. Y, Zhao, L. M, Kang, C. L, Chen, L. Z, Jing, F, Yao, N, Zhao, Y. H, Li, X. M, Li, Y, Dong, J. T

“…This paper presents a validation and confutation analysis using the methods of the robust satellite data analysis technique (RST) to detect seismic anomalies…”
Get full text

Towards merged-element transmons using silicon fins: The FinMET by Goswami, A., McFadden, A. P., Zhao, T., Inbar, H., Dong, J. T., Zhao, R., McRae, C. R. H., Simmonds, R. W., Palmstrøm, C. J., Pappas, D. P.

“…A merged-element transmon (MET) device based on silicon (Si) fins is proposed, and the first steps to form such a “FinMET” are demonstrated. This new…”
Get full text

Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer Cells by Zhang, Zhiqian, Zhang, Baotong, Li, Weidong, Fu, Liya, Fu, Li, Zhu, Zhengmao, Dong, Jin-Tang

“…It has become increasingly clear that microRNAs (miRNAs) play important roles in tumorigenesis and metastasis. Recently, miR-203 was reported as a suppressor…”
Get full text

CD44 is a metastasis suppressor gene for prostatic cancer located on human chromosome 11p13 by ALLEN CHUAN GAO, A. C, LOU, W, DONG, J.-T, ISAACS, J. T

“…We have used microcell fusion-mediated chromosomal transfer to introduce normal human chromosomes into highly metastatic rodent prostatic cancer cells to map…”
Get full text

Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss by DONG, J.-T, SUZUKI, H, PIN, S. S, BOVA, G. S, SCHALKEN, J. A, ISAACS, W. B, BARRETT, J. C, ISAACS, J. T

“…The KAI1 gene, located on human chromosome 11p11.2, suppresses tumor metastasis when expressed in certain cancer cells. To evaluate whether dysregulation of…”
Get full text

PTEN/MMAC1 is infrequently mutated in pT2 and pT3 carcinomas of the prostate by DONG, J.-T, SIPE, T. W, HYYTINEN, E.-R, LI, C.-L, HEISE, C, MCCLINTOCK, D. E, GRANT, C. D, CHUNG, L. W. K, FRIERSON, H. F

“…Deletion of the q23-24 region of human chromosome 10 is one of the most frequent genetic alterations in prostate cancer, suggesting that inactivation of a…”
Get full text

Methylation of the CD44 metastasis suppressor gene in human prostate cancer by LOU, W, KRILL, D, DHIR, R, BECICH, M. J, DONG, J.-T, FRIERSON, H. F, ISAACS, W. B, ISAACS, J. T, GAO, A. C

“…Previous studies demonstrated that CD44 is a metastasis suppressor gene for prostate cancer and that the expression of CD44 both at mRNA and protein levels is…”
Get full text

Large second-order Josephson effect in planar superconductor-semiconductor junctions by Zhang, Po, Zarassi, Azarin, Jarjat, Lucas, Van de Sande, Vince, Pendharkar, Mihir, Lee, J. S., Dempsey, Connor P., McFadden, Anthony, Harrington, Sean David, Dong, Jason T., Wu, H., Chen, A. -H., Hocevar, Moïra, Palmstrøm, C. J., Frolov, Sergey M.

“…We investigate the current-phase relations of Al/InAs-quantum well planar Josephson junctions fabricated using nanowire shadowing technique. Based on several…”
Get full text

Deletion at 13q21 is associated with aggressive prostate cancers by DONG, J.-T, CESHI CHEN, STULTZ, B. G, ISAACS, J. T, FRIERSON, H. F

“…Previous cytogenetic and molecular genetic analyses suggest that the q21 band of chromosome 13 harbors a tumor suppressor gene(s) involved in prostatic…”
Get full text

Mutations of PTEN/MMAC1 in Primary Prostate Cancers from Chinese Patients by DONG, Jin-Tang, LI, Chang-Ling, SIPE, Tavis W, FRIERSON, Henry F

“…PTEN/MMAC1 is a putative tumor suppressor gene located on 10q23, one of the most frequently deleted chromosomal regions in human prostate cancer. Although…”
Get full text

Frequent Down-Regulation and Lack of Mutation of the KAI1 Metastasis Suppressor Gene in Epithelial Ovarian Carcinoma by Liu, Fu-Shing, Dong, Jin-Tang, Chen, Jung-Ta, Hsieh, Yeun-Ting, Shih-Chu Ho, Esther, Hung, Man-Jung

“…Objective. KAI1 is a recently identified metastasis suppressor gene on human chromosome 11p11.2. It belongs to a structurally distinct family of cell surface…”
Get full text

The study on specific umbilical blood Dc vaccine for Beige nude mice loaded human colorectal carcinoma to induce anti-tumor immunity by Fu, Z-X, Han, J-S, Liu, F, Zhao, Z-L, Li, D-B, Shi, L, Dong, J-T, Zhou, Y, Cai, J-H

“…This study is to observe the immunosuppression of CD137L transfected umbilical blood Dcs (Dendritic cell) vaccine to tumor development of SCID/ Beige nude…”
Get more information

Chromosomal deletions and tumor suppressor genes in prostate cancer by Dong, J T

“…Chromosomal deletion appears to be the earliest as well as the most frequent somatic genetic alteration during carcinogenesis. It inactivates a tumor…”
Get full text

A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer by Chen, Ceshi, Bhalala, Hina V, Qiao, Hui, Dong, Jin-Tang

“…The 13q21 tumor suppressor locus, as defined by chromosomal deletion, harbors the KLF5 transcription factor which may have tumor suppressor function. To…”
Get full text

Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells by CESHI CHEN, XIAODONG SUN, QIMEI RAN, WILKINSON, Keith D, MURPHY, T. J, SIMONS, Jonathan W, DONG, Jin-Tang

“…Ubiquitin-mediated proteolysis plays a central role in controlling intracellular levels of essential regulatory molecules such as p53, cyclins, myc, BRCA1,…”
Get full text

Prostate cancer--biology of metastasis and its clinical implications by Dong, J T, Rinker-Schaeffer, C W, Ichikawa, T, Barrett, J C, Isaacs, J T

“…Prostate cancer is one of the most commonly diagnosed cancers and is a major cause of cancer death in men. Although the majority of the diagnosed prostate…”
Get full text

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2 by JIN-TANG DONG, LAMB, P. W, RINKER-SCHAEFFER, C. W, VUKANOVIC, J, ICHIKAWA, T, ISAACS, J. T, BARRETT, J. C

“…A gene from human chromosome 11p11.2 was isolated and was shown to suppress metastasis when introduced into rat AT6.1 prostate cancer cells. Expression of this…”
Get full text