Search Results - "Dong, J. T"
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Krüppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1
Published in Oncogene (22-10-2009)“…The Krüppel-like factor 5 (KLF5) is a zinc-finger transcription factor promoting cell proliferation, cell-cycle progression and survival. A high expression…”
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Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer
Published in Oncogene (05-04-2007)“…The gene for E3 ubiquitin ligase WWP1 is located at 8q21, a region frequently amplified in human cancers, including prostate cancer. Recent studies have shown…”
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3
Fibulin-5 protects the extracellular matrix of chondrocytes by inhibiting the Wnt/β-catenin signaling pathway and relieves osteoarthritis
Published in European review for medical and pharmacological sciences (01-05-2020)“…Osteoarthritis (OA) is a common disease in the elderly and seriously affects the quality of life of patients. The purpose of this study was to explore the…”
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4
Detecting seismic IR anomalies in bi-angular Advanced Along-Track Scanning Radiometer data
Published in Natural hazards and earth system sciences (20-08-2013)“…This paper presents a validation and confutation analysis using the methods of the robust satellite data analysis technique (RST) to detect seismic anomalies…”
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5
Towards merged-element transmons using silicon fins: The FinMET
Published in Applied physics letters (08-08-2022)“…A merged-element transmon (MET) device based on silicon (Si) fins is proposed, and the first steps to form such a “FinMET” are demonstrated. This new…”
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Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer Cells
Published in Genes & cancer (01-08-2011)“…It has become increasingly clear that microRNAs (miRNAs) play important roles in tumorigenesis and metastasis. Recently, miR-203 was reported as a suppressor…”
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CD44 is a metastasis suppressor gene for prostatic cancer located on human chromosome 11p13
Published in Cancer research (Chicago, Ill.) (01-03-1997)“…We have used microcell fusion-mediated chromosomal transfer to introduce normal human chromosomes into highly metastatic rodent prostatic cancer cells to map…”
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Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss
Published in Cancer research (Chicago, Ill.) (01-10-1996)“…The KAI1 gene, located on human chromosome 11p11.2, suppresses tumor metastasis when expressed in certain cancer cells. To evaluate whether dysregulation of…”
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9
PTEN/MMAC1 is infrequently mutated in pT2 and pT3 carcinomas of the prostate
Published in Oncogene (15-10-1998)“…Deletion of the q23-24 region of human chromosome 10 is one of the most frequent genetic alterations in prostate cancer, suggesting that inactivation of a…”
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10
Methylation of the CD44 metastasis suppressor gene in human prostate cancer
Published in Cancer research (Chicago, Ill.) (15-05-1999)“…Previous studies demonstrated that CD44 is a metastasis suppressor gene for prostate cancer and that the expression of CD44 both at mRNA and protein levels is…”
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11
Large second-order Josephson effect in planar superconductor-semiconductor junctions
Published in SciPost physics (01-01-2024)“…We investigate the current-phase relations of Al/InAs-quantum well planar Josephson junctions fabricated using nanowire shadowing technique. Based on several…”
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12
Deletion at 13q21 is associated with aggressive prostate cancers
Published in Cancer research (Chicago, Ill.) (15-07-2000)“…Previous cytogenetic and molecular genetic analyses suggest that the q21 band of chromosome 13 harbors a tumor suppressor gene(s) involved in prostatic…”
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13
Mutations of PTEN/MMAC1 in Primary Prostate Cancers from Chinese Patients
Published in Clinical cancer research (01-02-2001)“…PTEN/MMAC1 is a putative tumor suppressor gene located on 10q23, one of the most frequently deleted chromosomal regions in human prostate cancer. Although…”
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14
Frequent Down-Regulation and Lack of Mutation of the KAI1 Metastasis Suppressor Gene in Epithelial Ovarian Carcinoma
Published in Gynecologic oncology (01-07-2000)“…Objective. KAI1 is a recently identified metastasis suppressor gene on human chromosome 11p11.2. It belongs to a structurally distinct family of cell surface…”
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The study on specific umbilical blood Dc vaccine for Beige nude mice loaded human colorectal carcinoma to induce anti-tumor immunity
Published in European review for medical and pharmacological sciences (01-05-2017)“…This study is to observe the immunosuppression of CD137L transfected umbilical blood Dcs (Dendritic cell) vaccine to tumor development of SCID/ Beige nude…”
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Chromosomal deletions and tumor suppressor genes in prostate cancer
Published in Cancer and metastasis reviews (2001)“…Chromosomal deletion appears to be the earliest as well as the most frequent somatic genetic alteration during carcinogenesis. It inactivates a tumor…”
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A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer
Published in Oncogene (26-09-2002)“…The 13q21 tumor suppressor locus, as defined by chromosomal deletion, harbors the KLF5 transcription factor which may have tumor suppressor function. To…”
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Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells
Published in Oncogene (05-05-2005)“…Ubiquitin-mediated proteolysis plays a central role in controlling intracellular levels of essential regulatory molecules such as p53, cyclins, myc, BRCA1,…”
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Prostate cancer--biology of metastasis and its clinical implications
Published in World journal of urology (1996)“…Prostate cancer is one of the most commonly diagnosed cancers and is a major cause of cancer death in men. Although the majority of the diagnosed prostate…”
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KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2
Published in Science (American Association for the Advancement of Science) (12-05-1995)“…A gene from human chromosome 11p11.2 was isolated and was shown to suppress metastasis when introduced into rat AT6.1 prostate cancer cells. Expression of this…”
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