Search Results - "Dong, Fangcong"

The aryl hydrocarbon receptor as a mediator of host-microbiota interplay by Dong, Fangcong, Perdew, Gary H.

“…Increasing evidence suggests a significant role for microbiota dependent metabolites and co-metabolites, acting as aryl hydrocarbon receptor (AHR) ligands, to…”
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Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity by Dong, Fangcong, Hao, Fuhua, Murray, Iain A., Smith, Philip B., Koo, Imhoi, Tindall, Alyssa M., Kris-Etherton, Penny M., Gowda, Krishne, Amin, Shantu G., Patterson, Andrew D., Perdew, Gary H.

“…Commensal microbiota-dependent tryptophan catabolism within the gastrointestinal tract is known to exert profound effects upon host physiology, including the…”
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Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats by Yang, Yu-Chen S. H., Chang, Hsuen-Wen, Lin, I-Hsuan, Chien, Li-Nien, Wu, Min-Ju, Liu, Yun-Ru, Chu, Peiguo G., Xie, Guoxiang, Dong, Fangcong, Jia, Wei, Chang, Vincent H. S., Yen, Yun

“…Proton pump inhibitors (PPIs) are used for the long-term treatment of gastroesophageal disorders and the non-prescription medicines for acid reflux. However,…”
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Metabolic response to Klebsiella pneumoniae infection in an experimental rat model by Dong, Fangcong, Wang, Bin, Zhang, Lulu, Tang, Huiru, Li, Jieshou, Wang, Yulan

“…Bacteremia, the presence of viable bacteria in the blood stream, is often associated with several clinical conditions. Bacteremia can lead to multiple organ…”
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Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites by Patel, Dhwani, Murray, Iain A, Dong, Fangcong, Annalora, Andrew J, Gowda, Krishne, Coslo, Denise M, Krzeminski, Jacek, Koo, Imhoi, Hao, Fuhua, Amin, Shantu G, Marcus, Craig B, Patterson, Andrew D, Perdew, Gary H

“…The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that plays an important role in gastrointestinal barrier function,…”
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Systemic Responses of Mice to Dextran Sulfate Sodium-Induced Acute Ulcerative Colitis Using 1H NMR Spectroscopy by Dong, Fangcong, Zhang, Lulu, Hao, Fuhua, Tang, Huiru, Wang, Yulan

“…The interplay between genetic mutation and environmental factors is believed to contribute to the etiology of inflammatory bowel disease (IBD). While focused…”
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High Throughput and Quantitative Measurement of Microbial Metabolome by Gas Chromatography/Mass Spectrometry Using Automated Alkyl Chloroformate Derivatization by Zhao, Linjing, Ni, Yan, Su, Mingming, Li, Hongsen, Dong, Fangcong, Chen, Wenlian, Wei, Runmin, Zhang, Lulu, Guiraud, Seu Ping, Martin, Francois-Pierre, Rajani, Cynthia, Xie, Guoxiang, Jia, Wei

“…The ability to identify and quantify small molecule metabolites derived from gut microbial–mammalian cometabolism is essential for the understanding of the…”
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Exclusion of sulfide:quinone oxidoreductase from mitochondria causes Leigh-like disease in mice by impairing sulfide metabolism by Kanemaru, Eiki, Shimoda, Kakeru, Marutani, Eizo, Morita, Masanobu, Miranda, Maria, Miyazaki, Yusuke, Sinow, Claire, Sharma, Rohit, Dong, Fangcong, Bloch, Donald B, Akaike, Takaaki, Ichinose, Fumito

“…Leigh syndrome is the most common inherited mitochondrial disease in children and is often fatal within the first few years of life. In 2020, mutations in the…”
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Metabonomic Changes Associated with Atherosclerosis Progression for LDLR –/– Mice by Li, Dan, Zhang, Lulu, Dong, Fangcong, Liu, Yan, Li, Ning, Li, Huihui, Lei, Hehua, Hao, Fuhua, Wang, Yulan, Zhu, Yi, Tang, Huiru

“…Atherosclerosis resulting from hyperlipidemia causes many serious cardiovascular diseases. To understand the systems changes associated with pathogenesis and…”
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Complex chemical signals dictate Ah receptor activation through the gut–lung axis by Dong, Fangcong, Murray, Iain A., Annalora, Andrew, Coslo, Denise M., Desai, Dhimant, Gowda, Krishne, Yang, Jian, Wang, Dingbowen, Koo, Imhoi, Hao, Fuhua, Amin, Shantu G., Patterson, Andrew D., Marcus, Craig, Perdew, Gary H.

“…The aryl hydrocarbon receptor (AHR) mediates intestinal barrier homeostasis. Many AHR ligands are also CYP1A1/1B1 substrates, which can result in rapid…”
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Effects of Early Life Exposures to the Aryl Hydrocarbon Receptor Ligand TCDF on Gut Microbiota and Host Metabolic Homeostasis in C57BL/6J Mice by Tian, Yuan, Rimal, Bipin, Bisanz, Jordan E, Gui, Wei, Wolfe, Trenton M, Koo, Imhoi, Murray, Iain A, Nettleford, Shaneice K, Yokoyama, Shigetoshi, Dong, Fangcong, Koshkin, Sergei, Prabhu, K Sandeep, Turnbaugh, Peter J, Walk, Seth T, Perdew, Gary H, Patterson, Andrew D

“…Exposure to persistent organic pollutants (POPs) and disruptions in the gastrointestinal microbiota have been positively correlated with a predisposition to…”
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Selective Ah Receptor Ligands Mediate Enhanced SREBP1 Proteolysis to Restrict Lipogenesis in Sebocytes by Muku, Gulsum E, Blazanin, Nicholas, Dong, Fangcong, Smith, Philip B, Thiboutot, Diane, Gowda, Krishne, Amin, Shantu, Murray, Iain A, Perdew, Gary H

“…The aryl hydrocarbon receptor (AHR) mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced toxicity that can lead to chloracne in humans. A characteristic…”
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Abstract 3710: Serum tryptophan metabolites mediate constitutive AHR activity in head and neck squamous cell carcinoma cells by Patel, Dhwani, Morgan, Ethan W., Dong, Fangcong, Murray, Iain A., Perdew, Gary H.

“…Abstract The aryl hydrocarbon receptor (AHR) is transcription factor, that is activated upon binding to various exogenous and endogenous ligands. AHR…”
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Microbiota Metabolism Promotes Synthesis of the Human Ah Receptor Agonist 2,8-Dihydroxyquinoline by Hubbard, Troy D, Liu, Qing, Murray, Iain A, Dong, Fangcong, Miller, Charles, Smith, Philip B, Gowda, Krishne, Lin, Jyh Ming, Amin, Shantu, Patterson, Andrew D, Perdew, Gary H

“…The aryl hydrocarbon receptor (AHR) is a major regulator of immune function within the gastrointestinal tract. Resident microbiota are capable of influencing…”
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Endogenous Tryptophan-Derived Ah Receptor Ligands are Dissociated from CYP1A1/1B1-Dependent Negative-Feedback by Dong, Fangcong, Annalora, Andrew J, Murray, Iain A, Tian, Yuan, Marcus, Craig B, Patterson, Andrew D, Perdew, Gary H

“…The aryl hydrocarbon receptor (AHR) exerts major roles in xenobiotic metabolism, and in immune and barrier tissue homeostasis. How AHR activity is regulated by…”
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Systemic Responses of Mice to Dextran Sulfate Sodium-Induced Acute Ulcerative Colitis Using 1 H NMR Spectroscopy by Dong, Fangcong, Zhang, Lulu, Hao, Fuhua, Tang, Huiru, Wang, Yulan

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Contribution of Circulating Host and Microbial Tryptophan Metabolites Toward Ah Receptor Activation by Morgan, Ethan W, Dong, Fangcong, Annalora, Andrew J, Murray, Iain A, Wolfe, Trenton, Erickson, Reece, Gowda, Krishne, Amin, Shantu G, Petersen, Kristina S, Kris-Etherton, Penny M, Marcus, Craig B, Walk, Seth T, Patterson, Andrew D, Perdew, Gary H

“…The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that plays an integral role in homeostatic maintenance by regulating cellular…”
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