Flavonoids and other constituents of Hymenostegia afzelii (Caesalpiniaceae)
Three new prenylated flavonoids named afzelin A-C (1–3), were isolated from the leaves of Hymenostegia afzelii. The structures of 1–3 were determined by means of spectroscopic methods. [Display omitted] ► We investigated the stem bark and leaves of Hymenostegia afzelii. ► We isolated and characteriz...
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| Published in: | Phytochemistry letters Vol. 4; no. 3; pp. 315 - 319 |
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| Main Authors: | , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Elsevier Ltd
01-09-2011
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| Subjects: | |
| Online Access: | Get full text |
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| Summary: | Three new prenylated flavonoids named afzelin A-C
(1–3), were isolated from the leaves of
Hymenostegia afzelii. The structures of
1–3 were determined by means of spectroscopic methods.
[Display omitted]
► We investigated the stem bark and leaves of
Hymenostegia afzelii. ► We isolated and characterized three new prenylated flavonoids named afzelin A-C (
1–
3) from the leaves. ► No prenylated flavonoids were present in the stem bark. The new compounds exhibited cytotoxicity
in vitro on Brine shrimp.
Phytochemical investigation of the stem bark and leaves of
Hymenostegia afzelii resulted in the isolation of three new flavonoids, named afzelin A-C (
1–3), together with five known compounds: 7,6-(2″,2″-dimethylpyrano)-3,5,4′-trihydroxyflavone, apigenin, 3-
O-α-
l-rhamnopyranosylcincholic acid, 3-
O-β-
d-glucopyranosylcincholic acid, and dodecanoic acid 1,1′-[(1
S)-1-(hydroxymethyl)-1,2-ethanediyl] ester. The structures of
1–3 were determined by means of spectroscopic methods. Compounds
1–3 were tested
in vitro for their preliminary cytotoxicity using the
Artemia salina assay. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1874-3900 1876-7486 |
| DOI: | 10.1016/j.phytol.2011.06.002 |