Search Results - "Donets, Pavel A."

Ligand-Controlled Regiodivergent Nickel-Catalyzed Annulation of Pyridones by Donets, Pavel A., Cramer, Nicolai

“…The 1,6‐annulated 2‐pyridone motif is found in many biologically active compounds and its close relation to the indolizidine and quinolizidine alkaloid core…”
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Chiral Cp-Rhodium(III)-Catalyzed Asymmetric Hydroarylations of 1,1-Disubstituted Alkenes by Ye, Baihua, Donets, Pavel A., Cramer, Nicolai

“…Metal‐catalyzed functionalizations at the ortho position of a directing group have become an efficient bond‐forming strategy. A wide range of transformations…”
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Diaminophosphine Oxide Ligand Enabled Asymmetric Nickel-Catalyzed Hydrocarbamoylations of Alkenes by Donets, Pavel A, Cramer, Nicolai

“…Chiral trivalent phosphorus species are the dominant class of ligands and the key controlling element in asymmetric homogeneous transition-metal catalysis…”
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Nickel(0)-Catalyzed Enantioselective Annulations of Alkynes and Arylenoates Enabled by a Chiral NHC Ligand: Efficient Access to Cyclopentenones by Ahlin, Joachim S. E., Donets, Pavel A., Cramer, Nicolai

“…Cyclopentenones are versatile structural motifs of natural products as well as reactive synthetic intermediates. The nickel‐catalyzed reductive [3+2]…”
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Efficient Synthesis of the 3-Benzazepine Framework via Intramolecular Heck Reductive Cyclization by Donets, Pavel A, Van der Eycken, Erik V

“…A microwave-assisted protocol based on reductive Heck reaction was developed for regio- and stereoselective construction of the 3-benzazepine core…”
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Efficient Synthesis of the Indoloazocine Framework via Intramolecular Alkyne Carbocyclization by Donets, Pavel A, Van Hecke, Kristof, Van Meervelt, Luc, Van der Eycken, Erik V

“…A microwave-assisted protocol based on an Hg(OTf)2 catalyzed intramolecular alkyne carbocyclization reaction was developed for selective construction of the…”
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Synthesis of the Azocino[cd]indole Framework through Pd-Catalyzed Intramolecular Acetylene Hydroarylation by Peshkov, Vsevolod A., Van Hove, Sofie, Donets, Pavel A., Pereshivko, Olga P., Van Hecke, Kristof, Van Meervelt, Luc, Van der Eycken, Erik V.

“…The regio‐ and stereoselective construction of the azocino[cd]indole core was achieved by applying a Pd‐catalyzed intramolecular acetylene hydroarylation…”
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Diversity-Oriented Microwave-Assisted Synthesis of the 3-Benzazepine Framework by Peshkov, Vsevolod A., Pereshivko, Olga P., Donets, Pavel A., Mehta, Vaibhav P., Van der Eycken, Erik V.

“…An efficient diversity‐oriented procedure for the two‐step synthesis of 3‐benzazepines is described. The CuI‐catalyzed three‐component coupling of an aldehyde,…”
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Synthetic Approach toward Enantiopure Cyclic Sulfinamides by Jersovs, Glebs, Bojars, Matiss, Donets, Pavel A., Suna, Edgars

“…A synthetic approach toward densely substituted enantiopure cyclic sulfinamides possessing up to four consecutive stereogenic centers was developed based on a…”
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A 1,3,2‐Diazaphospholene‐Catalyzed Reductive Claisen Rearrangement by Reed, John H., Donets, Pavel A., Miaskiewicz, Solène, Cramer, Nicolai

“…1,3,2‐Diazaphospholenes (DAPs) are an emerging class of organic hydrides. In this work, we exploited them as efficient catalysts for very mild reductive…”
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Chiral 1,3,2‐Diazaphospholenes as Catalytic Molecular Hydrides for Enantioselective Conjugate Reductions by Miaskiewicz, Solène, Reed, John H., Donets, Pavel A., Oliveira, Caio C., Cramer, Nicolai

“…Secondary 1,3,2‐diazaphospholenes have a polarized P−H bond and are emerging as molecular hydrides. Herein, a class of chiral, conformationally restricted…”
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Chiral Cp-Rhodium(III)-Catalyzed Asymmetric Hydroarylations of 1,1-Disubstituted Alkenes by Ye, Baihua, Donets, Pavel A., Cramer, Nicolai

“…Metal‐catalyzed functionalizations at the ortho position of a directing group have become an efficient bond‐forming strategy. A wide range of transformations…”
Get full text

Nickel(0)-Catalyzed Enantioselective Annulations of Alkynes and Arylenoates Enabled by a Chiral NHC Ligand: Efficient Access to Cyclopentenones by Ahlin, Joachim S. E., Donets, Pavel A., Cramer, Nicolai

“…Cyclopentenones are versatile structural motifs of natural products as well as reactive synthetic intermediates. The nickel‐catalyzed reductive [3+2]…”
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A 1,3,2‐Diazaphospholene‐Catalyzed Reductive Claisen Rearrangement by Reed, John H., Donets, Pavel A., Miaskiewicz, Solène, Cramer, Nicolai

“…1,3,2‐Diazaphospholenes (DAPs) are an emerging class of organic hydrides. In this work, we exploited them as efficient catalysts for very mild reductive…”
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Ligand-Controlled Regiodivergent Nickel-Catalyzed Annulation of Pyridones by Donets, Pavel A., Cramer, Nicolai

“…The 1,6‐annulated 2‐pyridone motif is found in many biologically active compounds and its close relation to the indolizidine and quinolizidine alkaloid core…”
Get full text

Efficient Synthesis of the Indoloazocine Framework via Intramolecular Alkyne Carbocyclization by Donets, Pavel A, Van Hecke, Kristof, Van Meervelt, Luc, Van der Eycken, Erik V

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Chiral 1,3,2‐Diazaphospholenes as Catalytic Molecular Hydrides for Enantioselective Conjugate Reductions by Miaskiewicz, Solène, Reed, John H., Donets, Pavel A., Oliveira, Caio C., Cramer, Nicolai

“…Secondary 1,3,2‐diazaphospholenes have a polarized P−H bond and are emerging as molecular hydrides. Herein, a class of chiral, conformationally restricted…”
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Chiral Monodentate Trialkylphosphines Based on the Phospholane Architecture by Donets, Pavel A., Saget, Tanguy, Cramer, Nicolai

“…The development of efficient chiral monodentate phosphine ligands lags behind that of the bidentate congeners. This holds especially true for highly electron…”
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Optimized Synthesis of Indole Carboxylate Metallo-β-Lactamase Inhibitor EBL-3183 by Baran, Andrei, Kuzmins, Jevgenijs, Kuznecovs, Jevgenijs, Farley, Alistair J. M., Panduwawala, Tharindi, Parkova, Anete, Donets, Pavel A., Brem, Jürgen, Suna, Edgars, Schofield, Christopher J., Shubin, Kirill

“…A new synthetic route for the preparation of the metallo-β-lactamase inhibitor pre-candidate EBL-3183 was developed and carried out on a kilogram scale. The…”
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An Asymmetric Approach towards (–)‐Aphanorphine and Its Analogues by Donets, Pavel A., Goeman, Jan L., Van der Eycken, Johan, Robeyns, Koen, Van Meervelt, Luc, Van der Eycken, Erik V.

“…A short enantioselective approach towards the alkaloid(–)‐aphanorphine and its substituted analogues is described. The enantiomerically pure starting material…”
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