Search Results - "Donck, Kris Ver"
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Functional Characterization of Three G Protein-coupled Receptors for Pigment Dispersing Factors in Caenorhabditis elegans
Published in The Journal of biological chemistry (30-05-2008)“…Here, we report the identification, cloning, and functional characterization of three Caenorhabditis elegans G protein-coupled pigment dispersing factor (PDF)…”
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A novel library screen identifies immunosuppressors that promote osteoblast differentiation
Published in Bone (New York, N.Y.) (01-06-2012)“…Abstract Bone homeostasis can be compromised by an increase in osteoclast-mediated resorption and/or a decrease in osteoblast-mediated bone deposition. While…”
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3
Cytomics and drug discovery
Published in Cytometry. Part A (01-03-2006)“…Pharmaceutical companies try to develop new drugs that have a high success rate of reaching the market. However, current disease models lack a strong…”
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Physiological red blood cell kinetic model to explain the apparent discrepancy between adenosine breakdown inhibition and nucleoside transporter occupancy of draflazine
Published in The Journal of pharmacology and experimental therapeutics (01-07-1998)“…A physiological red blood cell (RBC) kinetic model is proposed for the adenosine (ADO) transport into erythrocytes and its subsequent intracellular deamination…”
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Functional Characterization of Three G Protein-coupled Receptors for Pigment Dispersing Factors in Caenorhabditis elegansS
Published in The Journal of biological chemistry (30-05-2008)“…Here, we report the identification, cloning, and functional characterization of three Caenorhabditis elegans G protein-coupled pigment dispersing factor (PDF)…”
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6
Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. Implications for its future role in cardioprotection
Published in The Journal of clinical investigation (01-02-1995)“…In 12 healthy male volunteers (27-53 yr), a placebo-controlled randomized double blind cross-over trial was performed to study the effect of the intravenous…”
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Role of nucleoside transport inhibition and endogenous adenosine in prevention of catecholamine induced death in rabbits
Published in Cardiovascular research (01-01-1993)“…R 75,231, a potent and specific nucleoside transport inhibitor, largely prevents cardiac damage and death in catecholamine challenged rabbits. The major…”
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Prevention of catecholamine-induced cardiac damage and death with a nucleoside transport inhibitor
Published in Journal of cardiovascular pharmacology (01-08-1992)“…The effect of a potent and specific nucleoside transport inhibitor, R 75,231, on catecholamine-induced cardiac toxicity has been studied in rabbits…”
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High-grade nucleoside transport inhibition stimulates ventilation in humans
Published in Journal of clinical pharmacology (01-04-1995)“…In 6 healthy male volunteers a placebo-controlled, double-blind, randomized, crossover trial was done to assess the effect of 1, 2, 4, and 6 mg of draflazine,…”
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10
Nucleoside transport inhibition and fMLP-stimulated whole blood luminescence
Published in Journal of molecular and cellular cardiology (01-07-1991)“…Adenosine (ADO) has a pharmacological profile which makes it an interesting 'drug' to handle many of the problems arising with ischemia and reperfusion. In…”
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Structural interpretation of the amino acid sequence of a second domain from the Artemia covalent polymer globin
Published in The Journal of biological chemistry (25-08-1990)“…Artemia has a complex extracellular hemoglobin of Mr 260,000 comprising two globin chains (Mr 130,000) each of which is a polymer of eight covalently linked…”
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12
Purine metabolism in the heart. Strategies for protection against myocardial ischaemia
Published in Pharmacy world and science (15-04-1994)“…Adenosine has recently received much attention for the protection it provides against the deleterious effects of ischaemia reperfusion. Whenever the demand for…”
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