Search Results - "Donatella, Contini"

Precision medicine: a new era for inner ear diseases by Tavazzani, Elisa, Spaiardi, Paolo, Contini, Donatella, Sancini, Giulio, Russo, Giancarlo, Masetto, Sergio

“…The inner ear is the organ responsible for hearing and balance. Inner ear dysfunction can be the result of infection, trauma, ototoxic drugs, genetic mutation…”
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Simultaneous recordings from vestibular Type I hair cells and their calyceal afferents in mice by Contini, Donatella, Holstein, Gay R, Art, Jonathan J

“…The vestibular hair cell receptors of anamniotes, designated Type II, are presynaptic to bouton endings of vestibular nerve distal neurites. An additional…”
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Corrigendum: Precision medicine: a new era for inner ear diseases by Tavazzani, Elisa, Spaiardi, Paolo, Contini, Donatella, Sancini, Giulio, Russo, Giancarlo, Masetto, Sergio

“…[This corrects the article DOI: 10.3389/fphar.2024.1328460.]…”
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Simultaneous Dual Recordings From Vestibular Hair Cells and Their Calyx Afferents Demonstrate Multiple Modes of Transmission at These Specialized Endings by Contini, Donatella, Holstein, Gay R, Art, Jonathan J

“…In the vestibular periphery, transmission conventional synaptic boutons is supplemented by post-synaptic calyceal endings surrounding Type I hair cells. This…”
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SPATIOTEMPORAL ASPECTS OF LIVE CELL NEURONAL SIGNALING USING LOW AND HIGH SPATIAL COHERENCE LATTICE LIGHT-SHEET DETECTION APPROACHES by Potcoava, Mariana, Contini, Donatella, Zurawski, Zachary, Huynh, Spencer, Mann, Christopher, Art, Jonathan, Alford, Simon

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Live Cell Light Sheet Imaging with Low- and High-Spatial-Coherence Detection Approaches Reveals Spatiotemporal Aspects of Neuronal Signaling by Potcoava, Mariana, Contini, Donatella, Zurawski, Zachary, Huynh, Spencer, Mann, Christopher, Art, Jonathan, Alford, Simon

“…Light sheet microscopy in live cells requires minimal excitation intensity and resolves three-dimensional (3D) information rapidly. Lattice light sheet…”
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Confirming a Role for α9nAChRs and SK Potassium Channels in Type II Hair Cells of the Turtle Posterior Crista by Parks, Xiaorong Xu, Contini, Donatella, Jordan, Paivi M, Holt, Joseph C

“…In turtle posterior cristae, cholinergic vestibular efferent neurons (VENs) synapse on type II hair cells, bouton afferents innervating type II hair cells, and…”
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Distinct roles of Eps8 in the maturation of cochlear and vestibular hair cells by Elisa, Tavazzani, Paolo, Spaiardi, Valeria, Zampini, Donatella, Contini, Marco, Manca, Giancarlo, Russo, Ivo, Prigioni, Walter, Marcotti, Sergio, Masetto

“…Graphical abstract…”
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Accumulation of K+ in the synaptic cleft modulates activity by influencing both vestibular hair cell and calyx afferent in the turtle by Contini, Donatella, Price, Steven D., Art, Jonathan J.

“…Key points In the synaptic cleft between type I hair cells and calyceal afferents, K+ ions accumulate as a function of activity, dynamically altering the…”
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Synaptic cleft microenvironment influences potassium permeation and synaptic transmission in hair cells surrounded by calyx afferents in the turtle by Contini, Donatella, Holstein, Gay R., Art, Jonathan J.

“…Key points In central regions of vestibular semicircular canal epithelia, the [K+] in the synaptic cleft ([K+]c) contributes to setting the hair cell and…”
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Muscarinic Acetylcholine Receptors and M-Currents Underlie Efferent-Mediated Slow Excitation in Calyx-Bearing Vestibular Afferents by Holt, J Chris, Jordan, Paivi M, Lysakowski, Anna, Shah, Amit, Barsz, Kathy, Contini, Donatella

“…Stimulation of vestibular efferent neurons excites calyx and dimorphic (CD) afferents. This excitation consists of fast and slow components that differ…”
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Accumulation of K super(+) in the synaptic cleft modulates activity by influencing both vestibular hair cell and calyx afferent in the turtle by Contini, Donatella, Price, Steven D, Art, Jonathan J

“…Key points * In the synaptic cleft between type I hair cells and calyceal afferents, K super(+) ions accumulate as a function of activity, dynamically altering…”
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A review of synaptic mechanisms of vestibular efferent signaling in turtles: extrapolation to efferent actions in mammals by Jordan, Paivi M, Parks, Xiaorong Xu, Contini, Donatella, Holt, J Chris

“…The vestibular labyrinth of nearly every vertebrate class receives a prominent efferent innervation that originates in the brainstem and ends as bouton…”
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