Search Results - "Donaldson, Ken"

Refine Results
  1. 1

    Global association of air pollution and heart failure: a systematic review and meta-analysis by Shah, Anoop SV, MBChB, Langrish, Jeremy P, MBChB, Nair, Harish, PhD, McAllister, David A, MD, Hunter, Amanda L, MBChB, Donaldson, Ken, Prof, Newby, David E, Prof, Mills, Nicholas L, Dr

    Published in The Lancet (British edition) (21-09-2013)
    “…Summary Background Acute exposure to air pollution has been linked to myocardial infarction, but its effect on heart failure is uncertain. We did a systematic…”
    Get full text
    Journal Article
  2. 2
  3. 3

    A short history of the toxicology of inhaled particles by Donaldson, Ken, Seaton, Anthony

    Published in Particle and fibre toxicology (06-05-2012)
    “…Particle toxicology arose in order to understand the mechanisms of adverse effects of 3 major particle types that had historically exerted the greatest toll of…”
    Get full text
    Journal Article
  4. 4

    Pulmonary toxicity of carbon nanotubes and asbestos — Similarities and differences by Donaldson, Ken, Poland, Craig A., Murphy, Fiona A., MacFarlane, Marion, Chernova, Tatyana, Schinwald, Anja

    Published in Advanced drug delivery reviews (01-12-2013)
    “…Carbon nanotubes are a valuable industrial product but there is potential for human pulmonary exposure during production and their fibrous shape raises the…”
    Get full text
    Journal Article
  5. 5

    Use of back-scatter electron signals to visualise cell/nanowires interactions in vitro and in vivo; frustrated phagocytosis of long fibres in macrophages and compartmentalisation in mesothelial cells in vivo by Schinwald, Anja, Donaldson, Ken

    Published in Particle and fibre toxicology (28-08-2012)
    “…Frustrated phagocytosis has been stated as an important factor in the initiation of an inflammatory response after fibre exposure. The length of fibrous…”
    Get full text
    Journal Article
  6. 6
  7. 7

    Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma by Donaldson, Ken, Murphy, Fiona A, Duffin, Rodger, Poland, Craig A

    Published in Particle and fibre toxicology (22-03-2010)
    “…The unique hazard posed to the pleural mesothelium by asbestos has engendered concern in potential for a similar risk from high aspect ratio nanoparticles…”
    Get full text
    Journal Article
  8. 8

    Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes by Cho, Wan-Seob, Duffin, Rodger, Howie, Sarah E M, Scotton, Chris J, Wallace, William A H, Macnee, William, Bradley, Mark, Megson, Ian L, Donaldson, Ken

    Published in Particle and fibre toxicology (06-09-2011)
    “…Large production volumes of zinc oxide nanoparticles (ZnONP) might be anticipated to pose risks, of accidental inhalation in occupational and even in consumer…”
    Get full text
    Journal Article
  9. 9

    The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area by Monteiller, Claire, Tran, Lang, MacNee, William, Faux, Steve, Jones, Alan, Miller, Brian, Donaldson, Ken

    “…Objective: Rats exposed to high airborne mass concentrations of low-solubility low-toxicity particles (LSLTP) have been reported to develop lung disease such…”
    Get full text
    Journal Article
  10. 10

    The Biologically Effective Dose in Inhalation Nanotoxicology by Donaldson, Ken, Schinwald, Anja, Murphy, Fiona, Cho, Wan-Seob, Duffin, Rodger, Tran, Lang, Poland, Craig

    Published in Accounts of chemical research (19-03-2013)
    “…In all branches of toxicology, the biologically effective dose (BED) is thefraction of the total dose of a toxin that actually drives any toxic effect…”
    Get full text
    Journal Article
  11. 11

    Zeta potential and solubility to toxic ions as mechanisms of lung inflammation caused by metal/metal oxide nanoparticles by Cho, Wan-Seob, Duffin, Rodger, Thielbeer, Frank, Bradley, Mark, Megson, Ian L, Macnee, William, Poland, Craig A, Tran, C Lang, Donaldson, Ken

    Published in Toxicological sciences (01-04-2012)
    “…The toxicology of nanoparticles (NPs) is an area of intense investigation that would be greatly aided by improved understanding of the relationship between NP…”
    Get full text
    Journal Article
  12. 12

    Proinflammogenic Effects of Low-Toxicity and Metal Nanoparticles In Vivo and In Vitro: Highlighting the Role of Particle Surface Area and Surface Reactivity by Duffin, Rodger, Tran, Lang, Brown, David, Stone, Vicki, Donaldson, Ken

    Published in Inhalation toxicology (01-01-2007)
    “…Different particle types cause excessive lung inflammation that is thought to play a role in the various types of pathology they produce. Recently attention…”
    Get full text
    Journal Article
  13. 13

    The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells by Murphy, Fiona A, Schinwald, Anja, Poland, Craig A, Donaldson, Ken

    Published in Particle and fibre toxicology (03-04-2012)
    “…Carbon nanotubes (CNT) are high aspect ratio nanoparticles with diameters in the nanometre range but lengths extending up to hundreds of microns. The…”
    Get full text
    Journal Article
  14. 14

    Use of silver nanowires to determine thresholds for fibre length-dependent pulmonary inflammation and inhibition of macrophage migration in vitro by Schinwald, Anja, Chernova, Tanya, Donaldson, Ken

    Published in Particle and fibre toxicology (02-12-2012)
    “…The objective of this study was to examine the threshold fibre length for the onset of pulmonary inflammation after aspiration exposure in mice to four…”
    Get full text
    Journal Article
  15. 15
  16. 16

    The potential risks of nanomaterials: a review carried out for ECETOC by Borm, Paul J A, Robbins, David, Haubold, Stephan, Kuhlbusch, Thomas, Fissan, Heinz, Donaldson, Ken, Schins, Roel, Stone, Vicki, Kreyling, Wolfgang, Lademann, Jurgen, Krutmann, Jean, Warheit, David, Oberdorster, Eva

    Published in Particle and fibre toxicology (14-08-2006)
    “…During the last few years, research on toxicologically relevant properties of engineered nanoparticles has increased tremendously. A number of international…”
    Get full text
    Journal Article
  17. 17

    Comparison of cellular toxicity caused by ambient ultrafine particles and engineered metal oxide nanoparticles by Lu, Senlin, Zhang, Wenchao, Zhang, Rui, Liu, Pinwei, Wang, Qiangxiang, Shang, Yu, Wu, Minghong, Donaldson, Ken, Wang, Qingyue

    Published in Particle and fibre toxicology (19-03-2015)
    “…The development of nanotechnology has spurred concerns about the health effects of exposure to nanoparticles (NPs) and ultrafine particles (UFPs)…”
    Get full text
    Journal Article
  18. 18

    The threshold length for fiber-induced acute pleural inflammation: shedding light on the early events in asbestos-induced mesothelioma by Schinwald, Anja, Murphy, Fiona A, Prina-Mello, Adriele, Poland, Craig A, Byrne, Fiona, Movia, Dania, Glass, James R, Dickerson, Janet C, Schultz, David A, Jeffree, Chris E, Macnee, William, Donaldson, Ken

    Published in Toxicological sciences (01-08-2012)
    “…Suspicion has been raised that high aspect ratio nanoparticles or nanofibers might possess asbestos-like pathogenicity. The pleural space is a specific target…”
    Get full text
    Journal Article
  19. 19

    Inhaled nanoparticles and lung cancer - what we can learn from conventional particle toxicology by Donaldson, Ken, Poland, Craig A

    Published in Swiss medical weekly (2012)
    “…Manufactured nanoparticles (MNP) represent a growth area in industry where their interesting and useful properties bestow advantage over conventional particles…”
    Get full text
    Journal Article
  20. 20