Search Results - "Donald, A E"

Arterial distensibility in adolescents : The influence of adiposity, the metabolic syndrome, and classic risk factors by WHINCUP, P. H, GILG, J. A, DONALD, A. E, KATTERHORN, M, OLIVER, C, COOK, D. G, DEANFIELD, J. E

“…Atherosclerosis develops from childhood, but the determinants of this preclinical stage remain uncertain. We examined the relations of classic coronary risk…”
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Acute systemic inflammation impairs endothelium-dependent dilatation in humans by HINGORANI, A. D, CROSS, J, MACALLISTER, R. J, VALLANCE, P, KHARBANDA, R. K, MULLEN, M. J, BHAGAT, K, TAYLOR, M, DONALD, A. E, PALACIOS, M, GRIFFIN, G. E, DEANFIELD, J. E

“…We tested the hypothesis that endothelial dysfunction underlies the association between an acute inflammatory episode and the transiently increased risk of a…”
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Impact of aortic stenting on peripheral vascular function and daytime systolic blood pressure in adult coarctation by Chen, S S M, Donald, A E, Storry, C, Halcox, J P, Bonhoeffer, P, Deanfield, J E

“…To determine the relation of ambulatory systolic blood pressure to aortic obstruction and more extensive vascular dysfunction, assessed by central aortic,…”
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Flow-mediated dilation in 9- to 11-year-old children : The influence of intrauterine and childhood factors by LEESON, C. P. M, WHINCUP, P. H, COOK, D. G, DONALD, A. E, PAPACOSTA, O, LUCAS, A, DEANFIELD, J. E

“…Early life factors, particularly size at birth, may influence later risk of cardiovascular disease, but a mechanism for this influence has not been…”
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Exercise training enhances endothelial function in young men by Clarkson, Peter, Montgomery, Hugh E, Mullen, Michael J, Donald, Ann E, Powe, Amanda J, Bull, Teresa, Jubb, Michael, World, Michael, Deanfield, John E

“…OBJECTIVES The present study was designed to assess whether exercise training can enhance endothelium-dependent dilatation in healthy young men. BACKGROUND…”
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Cholesterol and arterial distensibility in the first decade of life : A population-based study by LEESON, C. P. M, WHINCUP, P. H, COOK, D. G, MULLEN, M. J, DONALD, A. E, SEYMOUR, C. A, DEANFIELD, J. E

“…Blood cholesterol levels are a key determinant of coronary heart disease risk in adults, but the importance of lipid levels in the general population during…”
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Impaired vascular reactivity in insulin-dependent diabetes mellitus is related to disease duration and low density lipoprotein cholesterol levels by Clarkson, Peter, Celermajer, David S., Donald, Ann E., Sampson, Mike, Sorensen, Keld E., Adams, Mark, Yue, Dennis K., John Betteridge, D., Deanfield, John E.

“…Objectives. This study sought to examine whether endothelial function is impaired in the large vessels of asymptomatic young adults with insulin-dependent…”
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Non‐invasive assessment of endothelial function in normal pregnancy by Savvidou, M. D., Kametas, N. A., Donald, A. E., Nicolaides, K. H.

“…Objective To assess endothelial function in normal pregnancy by non‐invasive methods. Methods Flow‐mediated dilatation of the brachial artery was measured by…”
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Atorvastatin but not l-arginine improves endothelial function in type I diabetes mellitus: a double-blind study by Mullen, Michael J., Wright, David, Donald, Ann E., Thorne, Sara, Thomson, Hyeyoung, Deanfield, John E.

“…OBJECTIVES We sought to determine the effects of oral l-arginine and the hexamethylglutaryl coenzyme A reductase inhibitor atorvastatin on endothelial function…”
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Endothelium-dependent dilatation is impaired in young healthy subjects with a family history of premature coronary disease by CLARKSON, P, CELERMAJER, D. S, POWE, A. J, DONALD, A. E, HENRY, R. M. A, DEANFIELD, J. E

“…A family history of premature coronary artery disease (CAD) in a first-degree relative is an independent risk factor for coronary disease. Both genetic and…”
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Physiology and biochemistry of endothelial function in children with chronic renal failure by Kari, Jameela A., Donald, Ann E., Vallance, David T., Bruckdorfer, K.R., Leone, Anna, Mullen, Michael J., Bunce, Timothy, Dorado, Belen, Deanfield, John E., Rees, Lesley

“…Physiology and biochemistry of endothelial function in children with chronic renal failure. Premature atherosclerosis is a major cause of morbidity and…”
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Endothelial dysfunction late after Kawasaki disease by DHILLON, R, CLARKSON, P, DONALD, A. E, POWE, A. J, NASH, M, NOVELLI, V, DILLON, M. J, DEANFIELD, J. E

“…Kawasaki disease (KD) is a systemic vasculitis of childhood with widespread vascular endothelial damage in the acute stage. Long-term complications, such as…”
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Early endothelial dysfunction in adults at risk from atherosclerosis: different responses to l-arginine by Thorne, Sara, Mullen, Michael J, Clarkson, Peter, Donald, Ann E, Deanfield, John E

“…Objectives. We sought to examine endothelial responses to l-arginine in three groups with isolated risk factors: hypercholesterolemia, smoking and…”
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Treatment of photoaged skin with a cream containing 0.05% isotretinoin and sunscreens by Griffiths, C. E. M., Maddin, S., Wiedow, O., Marks, R., Donald, A. E., Kahlon, G.

“…Aims: To determine the safety and efficacy of a cream formulation of 0.05% isotretinoin with sunscreens (SPF 15) (I+S) in the treatment of photoaged skin…”
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Effect of enalapril on endothelial function in young insulin-dependent diabetic patients : A randomized, double-blind study by MULLEN, M. J, CLARKSON, P, DONALD, A. E, THOMSON, H, THORNE, S. A, POWE, A. J, FURUNO, T, BULL, T, DEANFIELD, J. E

“…We sought to determine whether 6 months of treatment with the angiotensin-converting enzyme (ACE) inhibitor enalapril can improve conduit artery endothelial…”
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Enantiomers of HA-966 (3-Amino-1-Hydroxypyrrolid-2-One) Exhibit Distinct Central Nervous System Effects: (+)-HA-966 is a Selective Glycine/N- Methyl-D-Aspartate Receptor Antagonist, But (-)-HA-966 is a Potent γ-Butyrolactone-Like Sedative by Singh, L., Donald, A. E., Foster, A. C., Hutson, P. H., Iversen, L. L., Iversen, S. D., Kemp, J. A., Leeson, P. D., Marshall, G. R., Oles, R. J., Priestley, T., Thorn, L., Tricklebank, M. D., Vass, C. A., Williams, B. J.

“…The antagonist effect of (±)-3-amino-1-hydroxypyrrolid-2-one (HA-966) at the N-methyl-D-aspartate (NMDA) receptor occurs through a selective interaction with…”
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Assessment of endothelial function in normal twin pregnancy by Savvidou, M. D., Donald, A. E., Nicolaides, K. H.

“…Objective To assess the maternal endothelial function in normal twin pregnancy. Design Cross‐sectional study. Subjects Endothelial function was investigated in…”
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Mental stress induces transient endothelial dysfunction in humans by GHIADONI, Lorenzo, DONALD, Ann E, DEANFIELD, John E, CROPLEY, Mark, MULLEN, Michael J, OAKLEY, Gillian, TAYLOR, Mia, O'CONNOR, Georgina, BETTERIDGE, John, KLEIN, Nigel, STEPTOE, Andrew

“…Mental stress has been linked to increased morbidity and mortality in coronary artery disease and to atherosclerosis progression. Experimental studies have…”
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Heterogenous Nature of Flow-Mediated Dilatation in Human Conduit Arteries In Vivo: Relevance to Endothelial Dysfunction in Hypercholesterolemia by Mullen, Michael J, Kharbanda, Rajesh K, Cross, Jenny, Donald, Ann E, Taylor, Mia, Vallance, Patrick, Deanfield, John E, MacAllister, Raymond J

“…ABSTRACT —Flow-mediated dilatation (FMD) of conduit arteries is dependent on an intact endothelium, although the mechanisms are not fully understood. Using…”
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Prospective randomized trial of woven versus collagen-impregnated knitted prosthetic Dacron grafts in aortoiliac surgery by Quarmby, J. W., Burnand, K. G., Lockhart, S. J. M., Donald, A. E., Sommerville, K. M., Jamieson, C. W., Browse, N. L.

“…Background Despite the theoretical advantages of coating knitted grafts with a material designed to reduce blood loss, their performance has not been directly…”
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