Search Results - "Donahue, Jeannine"

Inflammatory breast cancer (IBC) advocacy-Past, present and future by Donahue, Jeannine, Earls, Joshlyn, Fraser, Valerie, Mason, Ginny, Pirowski, Heather, Stephens, Peggy

“…Patient advocates, referring to those individuals that have been diagnosed with the disease for which they advocate, are essential stake holders in healthcare…”
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Impact of HER2 low expression in the Oncotype DX RS in patients with operable hormone receptor positive early stage breast cancer by Munoz-Arcos, Laura Sofia, Nicolo', Eleonora, Newman, Lisa A., Cigler, Tessa, Andreopoulou, Eleni, Moore, Anne, Donahue, Jeannine, Cristofanilli, Massimo

“…575 Background: Two thirds of breast carcinomas are human epidermal growth factor receptor 2 (HER2) low. To date, it is still unclear whether hormone receptor…”
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CK+/CD45+ (dual-positive) circulating cells are associated with prognosis in patients with advanced breast cancer by Reduzzi, Carolina, Gerratana, Lorenzo, Zhang, Youbin, D'Amico, Paolo, Shah, Ami N., Davis, Andrew A., Manai, Maroua, Silvestri, Marco, Zhang, Qiang, Donahue, Jeannine, Cristofanilli, Massimo

“…1093 Background: Circulating tumor cells (CTCs) expressing epithelial markers (EPCAM, cytokeratin (CK)) and lacking CD45 (a leukocyte marker) have been…”
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Prognostic value of tumor-derived extracellular vesicles and circulating tumor cells in metastatic breast cancer (BC): A focus on inflammatory BC by Nicolò, Eleonora, Munoz-Arcos, Laura Sofia, D'Amico, Paolo, Zhang, Youbin, Gerratana, Lorenzo, Manai, Marwa, Serafini, Mara Serena, Strickland, Amanda Kaylan, Davis, Andrew A., Donahue, Jeannine, Liu, Huiping, Gradishar, William John, Shah, Ami N., Curigliano, Giuseppe, Reduzzi, Carolina, Cristofanilli, Massimo

“…1098 Background: Circulating tumor cells (CTCs) are an independent prognostic factor in metastatic breast cancer (MBC). The prognostic value of CTCs and the…”
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Impact of circulating tumor DNA (ctDNA) surveillance on clinical care for patients with stage I-III breast cancer: Findings from a multi-institutional study by Lipsyc-Sharf, Marla, Fitzsimmons, Kasey, Medford, Arielle J, Podany, Emily L, Sedrak, Mina S., McAndrew, Nicholas Patrick, Callahan, Rena Desai, Kapoor, Nimmi S., Master, Aashini K., Rivero-Hinojosa, Samuel, Fielder, Janie, Rodriguez, Angel A, Liu, Minetta C., Knape, Justine, Donahue, Jeannine, Gianni, Caterina, Davis, Andrew A., Cristofanilli, Massimo, Bardia, Aditya

“…549 Background: Tumor-informed ctDNA-based detection of minimal residual disease (MRD) in the adjuvant setting for patients (pts) with early breast cancer…”
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ESR1 mutations in circulating tumor DNA (ctDNA) are associated with CTCs and increased hormone receptors in metastatic tumor tissues of patients with metastatic breast cancer (MBC) by Zhang, Qiang, Qin, Weijun, D’Amico, Paolo, Jiao, Jianhua, Davis, Andrew A., Gerratana, Lorenzo, Donahue, Jeannine, Reduzzi, Carolina, Manai, Marwa, Jacob, Saya, Zhang, Youbin, Flaum, Lisa E., Behdad, Amir, Cristofanilli, Massimo, Platanias, Leonidas C., Shah, Ami N., Gradishar, William John

“…1057 Background: The monitoring of ctDNA and circulating tumor cells (CTCs) in patients with MBC predicts metastasis and prognosis. We previously reported that…”
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Abstract P2-01-04: Esr1 hotspot mutations in circulating tumor DNA mutation are associated with endocrine therapy resistance in metastatic breast cancer by Zhang, Qiang, D'Amico, Paolo, Qin, Weijun, Jiao, Jianhua, Davis, Andrew A., Gerratana, Lorenzo, Jacob, Saya L., Zhang, Youbin, Donahue, Jeannine, Qiang, Wenan, Shah, Ami N., Behdad, Amir, Flaum, Lisa, Gradishar, William, Platanias, Leonidas C, Cristofanilli, Massimo

“…Abstract Introduction: Metastatic breast cancer (MBC) is a challenging clinical condition because most tumors will develop resistance to endocrine treatment as…”
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Abstract P2-02-05: Dynamic circulating tumor cell changes in enumeration and HER2 expression during systemic therapy for metastatic breast cancer by Zhang, Qiang, Qin, Weijun, D'Amico, Paolo, Davis, Andrew A., Jiao, Jianhua, Gerratana, Lorenzo, Jacob, Saya L., Zhang, Youbin, Donahue, Jeannine, Qiang, Wenan, Shah, Ami N, Behdad, Amir, Flaum, Lisa, Gradishar, William, Platanias, Leonidas C, Cristofanilli, Massimo

“…Abstract Introduction: CTCs are tumor cells that circulate in the blood of patient with primary and MBC and, are responsible for seeing of metastasis. The…”
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Abstract P2-01-08: Esr1 Y537 mutations are associated with increased baseline circulating tumor cells enumeration for patients with estrogen receptor positive metastatic breast cancer by Zhang, Qiang, Jiao, Jianhua, D'Amico, Paolo, Davis, Andrew A., Qin, Weijun, Gerratana, Lorenzo, Jacob, Saya L., Zhang, Youbin, Donahue, Jeannine, Qiang, Wenan, Shah, Ami N., Flaum, Lisa, Gradishar, William, Platanias, Leonidas C., Cristofanilli, Massimo

“…Abstract Introduction: Estrogen Receptor (ER)-positive breast cancer is the most frequent breast cancer subtype. Endocrine therapy (ET) targeting the ER…”
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ctDNA detection before and during systemic therapy for inflammatory breast cancer by Alexander, Angela, Marx, Angela, Wiley, Jie, Kai, Megumi, Valero, Vicente, Woodward, Wendy A., Tin, Tony, Kalashnikova, Ekaterina, Bristow, Sara L, Renner, Derrick, Wu, Hsin-Ta, Donahue, Jeannine, Rodriguez, Angel Augusto, Sethi, Himanshu, Liu, Minetta C., George, Mridula Annette, Cristofanilli, Massimo, Lim, Bora

“…e12523 Background: Inflammatory breast cancer (IBC) is a rare, aggressive form of breast cancer and despite a multimodal treatment approach, it is associated…”
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Abstract PS2-06: The detection and enumeration of circulating tumor cells (CTCs) and circulating endothelial cells (CECs) in metastatic breast cancer by Zhang, Qiang, D'Amico, Paolo, Donahue, Jeannine, Gerratana, Lorenzo, Davis, Andrew A., Jacob, Saya Liz, Cai, Zheng, Vagia, Elena, Qiang, Wenan, Shah, Ami N., Kerby, Katy, Flaum, Lisa, Zhang, Youbin, Wehbe, Firas, Behdad, Amir, Gradishar, William, Platanias, Leonidas, Cristofanilli, Massimo

“…Abstract Introduction: Circulating tumor cells (CTCs) are the roots of metastasis which is the main cause for death in metastatic breast cancer (MBC). CTCs…”
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Defining resistance mechanisms to CDK4/6 inhibition in hormone receptor-positive HER2-negative metastatic breast cancer (MBC) through a machine learning approach applied to circulating tumor DNA (ctDNA) by Gerratana, Lorenzo, Reduzzi, Carolina, Davis, Andrew A., Velimirovic, Marko, Clifton, Katherine, Hensing, Whitney L, Shah, Ami N., Dai, Charles Sichao, D’Amico, Paolo, Donahue, Jeannine, Zhang, Qiang, Membrino, Alexandro, Wehbe, Firas Hazem, Medford, Arielle Janine, Gradishar, William John, Behdad, Amir, Ma, Cynthia X., Wander, Seth Andrew, Puglisi, Fabio, Cristofanilli, Massimo

“…3055 Background: Although cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) are a primary treatment for hormone receptor-positive/HER2 negative MBC, data…”
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Abstract PO3-14-12: SIRT3 as a new potential predictive biomarker for response to CDK4/6 inhibition in ER+/HER2- metastatic breast cancer patients by Manai, Maroua, Sahraoui, Ghada, Doghri, Raoudha, Gerratana, Lorenzo, D’Amico, Paolo, Zhang, Youbin, Donahue, Jeannine, Shah, Ami, Reduzzi, Carolina, Qiang, Wenan, Cristofanilli, Massimo

“…Abstract Background: Several prospective, randomized clinical trials showed that the CDK4/6 inhibitor palbociclib in combination with either letrozole or…”
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Abstract P2-26-06: Association between CK+/CD45+ circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) alterations in advanced breast cancer patients by REDUZZI, Carolina, Gerratana, Lorenzo, Zhang, Youbin, MANAI, Maroua, D’Amico, Paolo, Davis, Andrew A., Donahue, Jeannine, Shah, Ami N., Cristofanilli, Massimo

“…Abstract Background: Circulating tumor cells (CTCs) in breast cancer (BC) are commonly defined as epithelial cells (EPCAM and cytokeratin (CK) positive),…”
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Abstract PO3-14-11: Association between BRCA alterations detected by circulating tumor DNA and germline mutations in breast cancer patients: a retrospective mono-institutional analysis by Pontolillo, Letizia, Nicolò, Eleonora, Arcos, Laura Munoz, Reduzzi, Carolina, Serafini, Mara Serena, Strickland, Amanda Kaylan, Bayou, Nadia, Donahue, Jeannine, Molteni, Elisabetta, Gerratana, Lorenzo, Giannarelli, Diana, Andreopoulou, Eleni, Bria, Emilio, Cristofanilli, Massimo

“…Abstract Background: PARP inhibitors (PARPi) are a standard of care for breast cancer (BC) patients (pts) with germline BRCA (gBRCA) mutation, with benefit…”
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Circulating Tumor DNA and Unique Actionable Genomic Alterations in the Longitudinal Monitoring of Metastatic Breast Cancer: A Case of FGFR2-KIAA1598 Gene Fusion by Nicolò, Eleonora, Munoz-Arcos, Laura, Vagia, Elena, D'Amico, Paolo, Reduzzi, Carolina, Donahue, Jeannine, Lorico-Rappa, Marco, Manai, Maroua, Behdad, Amir, Zhang, Youbin, Curigliano, Giuseppe, Shah, Ami, Cristofanilli, Massimo

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Abstract PO3-06-05: Association of tumor-derived extracellular vesicles with circulating tumor DNA alterations in metastatic breast cancer patients: exploring differences in inflammatory breast cancer by Nicolò, Eleonora, Gerratana, Lorenzo, Foffano, Lorenzo, Arcos, Laura Munoz, Serafini, Mara Serena, Manai, Maroua, Pontolillo, Letizia, Bayou, Nadia, Molteni, Elisabetta, Strickland, Amanda Kaylan, Zhang, Youbin, D’Amico, Paolo, Davis, Andrew, Donahue, Jeannine, liu, Huiping, Gradishar, William, Shah, Ami, Curigliano, Giuseppe, Reduzzi, Carolina, Cristofanilli, Massimo

“…Abstract Background: Liquid biopsy provides a real-time assessment of metastatic breast cancer (MBC). Recently, the complementary prognostic value of…”
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Abstract PO4-15-06: Genomic landscape characterization after exposure to cyclin dependent kinase 4/6 inhibitors: a retrospective multi-institutional consortium analysis by Pontolillo, Letizia, Reduzzi, Carolina, Davis, Andrew, Gerratana, Lorenzo, Medford, Arielle, Clifton, Katherine, Hensing, Whitney L., Velimirovic, Marko, Shah, Ami N., Donahue, Jeannine, Arcos, Laura Munoz, Dai, Charles S., Keenan, Jennifer, Behdad, Amir, Gradishar, William, Bria, Emilio, Ma, Cynthia, Bardia, Aditya, Cristofanilli, Massimo

“…Abstract Background: Limited data are available to determine the best therapeutic strategy for hormone-receptor positive (HR+) HER2 negative (HER2-) advanced…”
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Abstract 977: Germline BRCA1/2 mutations detected by circulating tumor DNA testing in breast cancer patients: A retrospective mutiinstitutional analysis by Pontolillo, Letizia, Reduzzi, Carolina, Davis, Andrew A., Medford, Arielle J., Putur, Annika, Gerratana, Lorenzo, Clifton, Katherine, Hensing, Whitney L., Velimirovic, Marko, Warrior, Surbhi, Serafini, Mara S., Nicolò, Eleonora, Munoz-Arcos, Laura, Donahue, Jeannine, Dai, Charles S., Keenan, Jennifer C., Behdad, Amir, Gradishar, William J., Giannarelli, Diana, Bria, Emilio, Ma, Cynthia X., Bardia, Aditya, Cristofanilli, Massimo

“…Abstract Background: The use of circulating tumor (ct) DNA testing allows to detect resistant and actionable somatic alterations and it could be associated…”
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Abstract 7500: Distribution and prognostic significance of circulating tumor cells (CTCs) and tumor-derived extracellular vesicles (tdEVs) in patients (pts) with lobular metastatic breast cancer (MBC) by Nicolo, Eleonora, Gerratana, Lorenzo, Foffano, Lorenzo, Munoz-Arcos, Laura, Serafini, Mara S., Manai, Maroua, Pontolillo, Letizia, Bayou, Nadia, Molteni, Elisabetta, Strickland, Amanda K., Gianni, Caterina, Zhang, Youbin, D'Amico, Paolo, Davis, Andrew A., Donahue, Jeannine, Liu, Huiping, Gradishar, William J., Shah, Ami N., Curigliano, Giuseppe, Reduzzi, Carolina, Cristofanilli, Massimo

“…Abstract Background: Invasive lobular carcinoma (ILC) has distinctive clinical and molecular features compared with invasive ductal carcinoma (IDC). CTCs and…”
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