Search Results - "Donachie, M"
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THE EXOPLANET MASS-RATIO FUNCTION FROM THE MOA-II SURVEY: DISCOVERY OF A BREAK AND LIKELY PEAK AT A NEPTUNE MASS
Published in The Astrophysical journal (20-12-2016)“…ABSTRACT We report the results of the statistical analysis of planetary signals discovered in MOA-II microlensing survey alert system events from 2007 to 2012…”
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The lowest mass ratio planetary microlens: OGLE 2016–BLG–1195Lb
Published in Monthly notices of the Royal Astronomical Society (01-08-2017)“…Abstract We report discovery of the lowest mass ratio exoplanet to be found by the microlensing method in the light curve of the event OGLE 2016–BLG–1195. This…”
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Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites
Published in PLoS neglected tropical diseases (01-02-2019)“…Amphotericin B is an increasingly important tool in efforts to reduce the global disease burden posed by Leishmania parasites. With few other chemotherapeutic…”
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A study of the light travel time effect in short-period MOA eclipsing binaries via eclipse timing
Published in Monthly notices of the Royal Astronomical Society (11-11-2018)Get full text
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Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response
Published in PLoS neglected tropical diseases (01-09-2022)“…Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were…”
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Simultaneous presentation and cross-presentation of immune-stimulating complex-associated cognate antigen by antigen-specific B cells
Published in European journal of immunology (01-05-2008)“…We demonstrate that uptake of oligomeric cognate antigen (OVA-hen egg lysozyme, OVA-HEL) alone or incorporated in immune-stimulating complexes (ISCOMS)…”
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Sialylation of Campylobacter jejuni lipo-oligosaccharides: impact on phagocytosis and cytokine production in mice
Published in PloS one (28-03-2012)“…Guillain-Barré syndrome (GBS) is a post-infectious polyradiculoneuropathy, frequently associated with antecedent Campylobacter jejuni (C. jejuni) infection…”
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Radiotherapy and the oral environment the effects of radiotherapy on the hard and soft tissues of the mouth and its management
Published in The European journal of prosthodontics and restorative dentistry (01-06-2013)“…Radiation therapy plays an important role in the care of patients with head and neck cancer. When the oral cavity and the salivary glands are exposed to high…”
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The Combined CTA1-DD/ISCOM Adjuvant Vector Promotes Priming of Mucosal and Systemic Immunity to Incorporated Antigens by Specific Targeting of B Cells
Published in Journal of Immunology (15-03-2006)“…The cholera toxin A1 (CTA1)-DD/QuilA-containing, immune-stimulating complex (ISCOM) vector is a rationally designed mucosal adjuvant that greatly potentiates…”
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CTA1-DD-Immune Stimulating Complexes: a Novel, Rationally Designed Combined Mucosal Vaccine Adjuvant Effective with Nanogram Doses of Antigen
Published in The Journal of immunology (1950) (15-09-2001)“…Mucosally active vaccine adjuvants that will prime a full range of local and systemic immune responses against defined antigenic epitopes are much needed…”
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Immune-Stimulating Complexes Induce an IL-12-Dependent Cascade of Innate Immune Responses
Published in The Journal of immunology (1950) (01-05-1999)“…The development of subunit vaccines requires the use of adjuvants that act by stimulating components of the innate immune response. Immune-stimulating…”
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Induction of mucosal and systemic immune-responses by immunization with ovalbumin entrapped in poly(lactide-co-glycolide) microparticles
Published in Immunology (01-04-1994)“…We have examined the range of mucosal and systemic immune responses induced by oral or parenteral immunization with ovalbumin (OVA) entrapped in…”
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A role for dendritic cells in the priming of antigen‐specific CD4+ and CD8+ T lymphocytes by immune‐stimulating complexes in vivo
Published in International immunology (01-06-2003)“…Immune‐stimulating complexes (ISCOMS) are adjuvant vectors which are unusual in being able to prime both CD4+ and CD8+ T cells by parenteral and mucosal…”
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The dental management of adult patients with haemophilia and other congenital bleeding disorders
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-11-2003)“…The management of adult dental patients with congenital bleeding disorders has caused a considerable number of problems to the dental profession [1]. There is…”
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The role of antigen‐presenting cells and interleukin‐12 in the priming of antigen‐specific CD4+ T cells by immune stimulating complexes
Published in Immunology (01-09-2003)“…Summary Immune stimulating complexes (ISCOMs) containing the saponin adjuvant Quil A are vaccine adjuvants that promote a wide range of immune responses in…”
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Assessment of tooth wear in an ageing population
Published in Journal of dentistry (01-06-1995)“…A random sample of 2222 adults aged 45 years and over was taken from the age/sex registers of two general medical practices in Newcastle upon Tyne, and asked…”
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Dendritic cell maturation enhances CD8+ T‐cell responses to exogenous antigen via a proteasome‐independent mechanism of major histocompatibility complex class I loading
Published in Immunology (01-07-2003)“…Summary Immune stimulating complexes (ISCOMS) containing the saponin adjuvant Quil A are vaccine adjuvants that induce a wide range of immune responses in…”
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Referral for secondary restorative dental care in rural and urban areas of Scotland: findings from the Highlands & Islands Teledentistry Project
Published in British dental journal (23-02-2002)“…To compare the reported level of use of secondary care services for restorative dental care in rural and urban areas of Scotland. Postal questionnaire survey…”
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Oral vaccination with immune stimulating complexes
Published in Immunology letters (1999)“…There is a need for non-living adjuvant vectors which will induce a full range of local and systemic immune responses to orally administered purified antigens…”
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Immune-stimulating complexes containing quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route
Published in Immunology (01-03-1991)“…Induction of all forms of protective immunity by oral immunization with subunit vaccines is an ideal goal for the development of novel vaccines, but creates…”
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