Search Results - "Dominguez, Gemma"
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Cancer‐associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients
Published in Cancer science (01-04-2013)“…Tumor epithelial cells within a tumor coexist with a complex microenvironment in which a variety of interactions between its various components determine the…”
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2
Determination of Cadherin-17 in Tumor Tissues of Different Metastatic Grade Using a Single Incubation-Step Amperometric Immunosensor
Published in Analytical chemistry (Washington) (18-09-2018)“…This paper reports the development of an amperometric immunosensing platform for the determination of cadherin-17 (CDH-17), an atypical adhesion protein…”
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3
Different exosome cargo from plasma/bronchoalveolar lavage in non-small-cell lung cancer
Published in Genes chromosomes & cancer (01-09-2014)“…Tumor‐derived exosomes mediate tumorigenesis by facilitating tumor growth, metastasis, development of drug resistance, and immunosuppression. However, little…”
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Toward Liquid Biopsy: Determination of the Humoral Immune Response in Cancer Patients Using HaloTag Fusion Protein-Modified Electrochemical Bioplatforms
Published in Analytical chemistry (Washington) (20-12-2016)“…Autoantibodies raised against tumor-associated antigens have shown high promise as clinical biomarkers for reliable diagnosis, prognosis, and therapy…”
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5
Breaking the Limits in Analyzing Carbohydrate Recognition by NMR Spectroscopy: Resolving Branch‐Selective Interaction of a Tetra‐Antennary N‐Glycan with Lectins
Published in Angewandte Chemie International Edition (20-11-2017)“…The biological recognition of complex‐type N‐glycans is part of many key physiological and pathological events. Despite their importance, the structural…”
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6
Tumor-derived exosomes are enriched in ΔNp73, which promotes oncogenic potential in acceptor cells and correlates with patient survival
Published in Human molecular genetics (15-01-2014)“…Tumor-derived exosomes are emerging as local and systemic cell-to-cell mediators of oncogenic information through the horizontal transfer of mRNAs, microRNAs…”
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7
ΔNp73 and its effector targets promote colorectal peritoneal carcinosis and predict survival
Published in The Journal of pathology (01-07-2024)“…Peritoneal metastasis of colorectal origin appears in ~10–15% of patients at the time of diagnosis and in 30–40% of cases with disease progression…”
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Identification of tumor-associated antigens with diagnostic ability of colorectal cancer by in-depth immunomic and seroproteomic analysis
Published in Journal of proteomics (01-03-2020)“…Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer related death worldwide. Its diagnosis at early stages would…”
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9
Automatic Facial Palsy Diagnosis as a Classification Problem Using Regional Information Extracted from a Photograph
Published in Diagnostics (Basel) (23-06-2022)“…The incapability to move the facial muscles is known as facial palsy, and it affects various abilities of the patient, for example, performing facial…”
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10
β-Cryptoxanthin Synergistically Enhances the Antitumoral Activity of Oxaliplatin through ΔNP73 Negative Regulation in Colon Cancer
Published in Clinical cancer research (01-10-2015)“…The acquired resistance to chemotherapy represents the major limitation in the treatment of cancer. New strategies to solve this failure and improve patients'…”
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11
XPA, XPC, and XPD Modulate Sensitivity in Gastric Cisplatin Resistance Cancer Cells
Published in Frontiers in pharmacology (17-10-2018)“…Cisplatin is an election drug widely used in clinic for the treatment of advanced gastric cancer. However, the heterogeneity of the gastric tumors and its…”
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12
Loss of 5hmC identifies a new type of aberrant DNA hypermethylation in glioma
Published in Human molecular genetics (01-09-2018)“…Abstract Aberrant DNA hypermethylation is a hallmark of cancer although the underlying molecular mechanisms are still poorly understood. To study the possible…”
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13
TWIST1 is expressed in colorectal carcinomas and predicts patient survival
Published in PloS one (28-03-2011)“…TWIST1 is a transcription factor that belongs to the family of basic helix-loop-helix proteins involved in epithelial-to-mesenchymal transition and invasion…”
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14
Disposable Amperometric Immunosensor for the Determination of the E‐Cadherin Tumor Suppressor Protein in Cancer Cells and Human Tissues
Published in Electroanalysis (New York, N.Y.) (01-02-2019)“…This paper describes the results obtained in the development of the first electrochemical immunosensor described to date for the detection of E‐cadherin…”
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15
Towards Facial Gesture Recognition in Photographs of Patients with Facial Palsy
Published in Healthcare (Basel) (31-03-2022)“…Humans express their emotions verbally and through actions, and hence emotions play a fundamental role in facial expressions and body gestures. Facial…”
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16
Modulation of DNA-induced damage and repair capacity in humans after dietary intervention with lutein-enriched fermented milk
Published in PloS one (11-09-2013)“…Dietary factors provide protection against several forms of DNA damage. Additionally, consumer demand for natural products favours the development of bioactive…”
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Immune-Dependent and Independent Antitumor Activity of GM-CSF Aberrantly Expressed by Mouse and Human Colorectal Tumors
Published in Cancer research (Chicago, Ill.) (2013)“…Granulocyte-macrophage colony-stimulating factor (GM-CSF/CSF2) is a cytokine produced in the hematologic compartment that may enhance antitumor immune…”
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ΔNp73, TAp73 and Δ133p53 Extracellular Vesicle Cargo as Early Diagnosis Markers in Colorectal Cancer
Published in Cancers (07-05-2021)“…The early diagnosis of colorectal cancer is a key factor in the overall survival of the patients. The actual screening programs include different approaches…”
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Prognostic impact of ΔTAp73 Isoform Levels and Their Target Genes in Colon Cancer Patients
Published in Clinical cancer research (15-09-2011)“…Cumulative data support the role of ΔTAp73 variants in tumorigenic processes such as drug resistance. We evaluate the impact of TP73 isoforms and their…”
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Circulating Bmi-1 mRNA as a possible prognostic factor for advanced breast cancer patients
Published in Breast cancer research : BCR (01-01-2007)“…Deregulation of Polycomb member Bmi-1 is involved in cell proliferation and human oncogenesis. Modulation of Bmi-1 is found in several tumor tissues, including…”
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