Search Results - "Domingues, S."
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Topological analysis and interactive visualization of biological networks and protein structures
Published in Nature protocols (01-04-2012)“…Computational analysis and interactive visualization of biological networks and protein structures are common tasks for gaining insight into biological…”
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Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis
Published in PloS one (29-11-2010)“…There is consensus that experimental autoimmune encephalomyelitis (EAE) can be mediated by myelin specific T cells of Th1 as well as of Th17 phenotype, but the…”
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Analyzing and visualizing residue networks of protein structures
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-04-2011)“…The study of individual amino acid residues and their molecular interactions in protein structures is crucial for understanding structure–function…”
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A new measure for functional similarity of gene products based on Gene Ontology
Published in BMC bioinformatics (15-06-2006)“…Gene Ontology (GO) is a standard vocabulary of functional terms and allows for coherent annotation of gene products. These annotations provide a basis for new…”
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Biological and physicochemical properties of biosurfactants produced by Lactobacillus jensenii P6A and Lactobacillus gasseri P65
Published in Microbial cell factories (19-09-2017)“…Background Lactobacillus species produce biosurfactants that can contribute to the bacteria’s ability to prevent microbial infections associated with…”
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The Developmental Role of Agouti in Color Pattern Evolution
Published in Science (American Association for the Advancement of Science) (25-02-2011)“…Animal color patterns can affect fitness in the wild; however, little is known about the mechanisms that control their formation and subsequent evolution. We…”
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Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus–infected patients
Published in Hepatology (Baltimore, Md.) (01-12-2009)“…Boceprevir is a hepatitis C virus (HCV) nonstructural protein (NS) 3/4A protease inhibitor that is currently being evaluated in combination with peginterferon…”
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Convergence in pigmentation at multiple levels: mutations, genes and function
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (27-08-2010)“…Convergence—the independent evolution of the same trait by two or more taxa—has long been of interest to evolutionary biologists, but only recently has the…”
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Mechanical plasticity during oligodendrocyte differentiation and myelination
Published in Glia (01-01-2018)“…In the central nervous system, oligodendrocyte precursor cells are exclusive in their potential to differentiate into myelinating oligodendrocytes…”
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Hybrid silica monolith for microextraction by packed sorbent to determine drugs from plasma samples by liquid chromatography–tandem mass spectrometry
Published in Talanta (Oxford) (01-08-2015)“…The present study (1) reports on the synthesis of two hybrid silica monoliths functionalized with aminopropyl or cyanopropyl groups by the sol–gel process; (2)…”
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Metabolite and protein associations with general health in the population-based CHRIS study
Published in Scientific reports (04-11-2024)“…Identifying biomarkers able to discriminate individuals on different health trajectories is crucial to understand the molecular basis of age-related morbidity…”
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Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
Published in Nature genetics (01-11-2008)“…Inflammatory bowel disease (IBD) typically manifests as either ulcerative colitis (UC) or Crohn's disease (CD). Systematic identification of susceptibility…”
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Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis
Published in Journal of antimicrobial chemotherapy (01-03-2016)“…Broad-spectrum antimicrobial activity of quaternary ammonium surfactants (QAS) makes them attractive and cheap topical prophylactic options for sexually…”
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Temporal progress of gene expression analysis with RNA-Seq data: A review on the relationship between computational methods
Published in Computational and structural biotechnology journal (01-01-2023)“…•Review of computational methods for differential gene expression (DEG) analysis.•Contextualization of the steps involved in DEG analysis, their properties and…”
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Cryopreservation of domestic cat (Felis catus) ovarian tissue: Comparison of two vitrification methods
Published in Theriogenology (15-04-2018)“…We aimed to evaluate the effect of two vitrification methods on the morphology and functionality of vitrified feline preantral follicles. Feline ovarian tissue…”
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Vitamin E-analog Trolox prevents endoplasmic reticulum stress in frozen-thawed ovarian tissue of capuchin monkey (Sapajus apella)
Published in Cell and tissue research (01-02-2014)“…Ovarian fragments were exposed to 0.5 M sucrose and 1 M ethylene glycol (freezing solution; FS) with or without selenium or Trolox. Histological and…”
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Intracellular delivery of Parkin-RING0-based fragments corrects Parkin-induced mitochondrial dysfunction through interaction with SLP-2
Published in Journal of translational medicine (16-01-2024)“…Loss-of-function mutations in the PRKN gene, encoding Parkin, are the most common cause of autosomal recessive Parkinson's disease (PD). We have previously…”
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Seminal characteristics and cryopreservation of sperm from the squirrel monkey, Saimiri collinsi
Published in Theriogenology (15-09-2015)“…The Neotropical nonhuman primate squirrel monkey (Saimiri sp.) is one of the most commonly used species in research in several areas of knowledge. However,…”
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Direct and indirect impact of 10-valent pneumococcal conjugate vaccine introduction on pneumonia hospitalizations and economic burden in all age-groups in Brazil: A time-series analysis
Published in PloS one (07-09-2017)“…BackgroundTen-valent pneumococcal conjugate vaccine (PCV10) was introduced in the National Immunization Program of Brazil in March/2010. Although there are…”
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