Search Results - "Domingos, Levy Tenorio Sousa"
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Sphingolipid Inhibitors as an Alternative to Treat Candidiasis Caused by Fluconazole-Resistant Strains
Published in Pathogens (Basel) (07-07-2021)“…Candida species are fungal pathogens known to cause a wide spectrum of diseases, and Candida albicans and Candida glabrata are the most common associated with…”
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Antifungal activity of β-lapachone against a fluconazole-resistant Candida auris strain
Published in Brazilian journal of microbiology (01-09-2024)“…Candida spp. can be found in the human microbiome. However, immunocompromised patients are likely to develop invasive Candida infections, with mortality rates…”
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Synergistic interactions between β-lapachone and fluconazole in the inhibition of CaCdr2p and CaMdr1p in Candida albicans
Published in Revista iberoamericana de micología (01-07-2020)“…Mortality rate of invasive Candida infections is raising mainly amongst immunocompromised patients. These infections are hard-to-treat mainly due to the…”
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Secondary Metabolites Diversity of Aspergillus unguis and Their Bioactivities: A Potential Target to Be Explored
Published in Biomolecules (Basel, Switzerland) (06-12-2022)“…belongs to the Aspergillus section Nidulantes. This species is found in soils and organisms from marine environments, such as jellyfishes and sponges. The…”
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Casearia sylvestris essential oil and its fractions inhibit Candida albicans ABC transporters related to multidrug resistance (MDR)
Published in Rodriguésia (2021)“…Abstract ABC transporters constitute a superfamily of transmembrane proteins that act mediating the translocation of several substrates across the membrane,…”
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Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata
Published in Bioorganic & medicinal chemistry (01-06-2022)“…[Display omitted] Infections caused particularly by Candida glabrata are hard to treat due to the development of antifungal resistance that occurs mainly…”
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β-Lapachone enhances the antifungal activity of fluconazole against a Pdr5p-mediated resistant Saccharomyces cerevisiae strain
Published in Brazilian journal of microbiology (01-09-2020)“…Objectives The aim of this study was to evaluate the ability of lapachones in disrupting the fungal multidrug resistance (MDR) phenotype, using a model of…”
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Secondary Metabolites Diversity of IAspergillus unguis/I and Their Bioactivities: A Potential Target to Be Explored
Published in Biomolecules (Basel, Switzerland) (01-12-2022)“…Aspergillus unguis belongs to the Aspergillus section Nidulantes. This species is found in soils and organisms from marine environments, such as jellyfishes…”
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Journal Article