Search Results - "Domingos, Cláudia Regina Bonini"

Interleukin 17F Gene Polymorphism as a Potential Protective Factor in the Immunopathology of Ocular Toxoplasmosis by da Silva, Danilo Donizete, Frederico, Fábio Batista, Previato, Mariana, Siqueira, Rubens Camargo, Bonini‐Domingos, Claudia Regina, Souza, Victor Hugo, Castiglioni, Lilian, Brandão, Cinara Cássia, de Mattos, Luiz Carlos, Ayo, Christiane Maria

“…ABSTRACT Ocular toxoplasmosis (OT) is characterised by intraocular inflammation due to Toxoplasma gondii infection. Studies have found that interleukin 17…”
Get full text

Effects of benzo[a]pyrene on the blood and liver of Physalaemus cuvieri and Leptodactylus fuscus (Anura: Leptodactylidae) by Fanali, Lara Zácari, Franco-Belussi, Lilian, Bonini-Domingos, Cláudia Regina, de Oliveira, Classius

“…Benzo[a]pyrene (BaP) is a bio-accumulative toxic compound found in the atmosphere, water, and soil that may affect the life cycle of amphibians. In this study,…”
Get full text

Polymorphism in the IL-1β promoter is associated with IgG antibody response to circumsporozoite protein repeats of Plasmodium vivax by Capobianco, Marcela Petrolini, Cassiano, Gustavo Capatti, Storti-Melo, Luciane Moreno, Pimenta, Tamirys Simão, Rodrigues, Ana Paula Drummond, Arruda, José Eduardo Gomes, Pinto, Marcia Ribeiro, Baptista, Andrea Regina de Souza, Pratt-Riccio, Lilian Rose, Bonini-Domingos, Cláudia Regina, de Oliveira-Ferreira, Joseli, Machado, Ricardo Luiz Dantas

“…Abstract Background It is well established that infection by Plasmodium vivax is a result of host-parasite interactions. In the present study, association with…”
Get full text

Frequencies of ABO, MNSs, and Duffy Phenotypes Among Blood Donors and Malaria Patients from Four Brazilian Amazon Areas by Cavasini, Carlos Eugênio, De Mattos, Luiz Carlos, Toméalves, Renata, Couto, Álvaro Augusto, Calvosa, Vanja Sueli Pachiano, Domingos, Cláudia Regina Bonini, Castilho, Lilian, Rossit, Andréa Regina Baptista, Machado, Ricardo Luiz Dantas

“…We compared the serological phenotypic frequencies of ABO, MNSs, and Duffy in 417 blood donors and 309 malaria patients from four Brazilian Amazon areas. Our…”
Get full text

Potential utility of melatonin as an antioxidant therapy in the management of sickle cell anemia by da Silva, Danilo Grünig Humberto, Ricci Jr, Octávio, de Almeida, Eduardo Alves, Bonini-Domingos, Claudia Regina

“…This study aimed to assess antioxidant effects of melatonin treatment compared to N‐acetylcysteine (NAC) and to their combination in a sickle cell suspension…”
Get full text

The relationship between of ACE I/D and the MTHFR C677T polymorphisms in the pathophysiology of type 2 diabetes mellitus in a population of Brazilian obese patients by Pirozzi, Flavio Fontes, Belini Junior, Edis, Okumura, Jessika Viviani, Salvarani, Mariana, Bonini-Domingos, Claudia Regina, Ruiz, Milton Artur

“…Objectives This study aimed to evaluate the frequencies of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) and methylenetetrahydrofolate…”
Get full text

Twenty Years of Neonatal Screening for Sickle Cell Disease in Brazil: The Challenges of a Continental Country with High Genetic Heterogeneity by Santos, Helena Pimentel dos, Domingos, Claudia Regina Bonini, Castro, Simone Martins de

“…Abstract Sickle cell disease (SCD) is the most common inherited hematological disease worldwide. The benefits of diagnosis and early intervention have led to…”
Get full text

Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception? by Cavasini, Carlos Eugênio, Mattos, Luiz Carlos de, Couto, Álvaro Augusto D’Almeida, Bonini-Domingos, Cláudia Regina, Valencia, Socrates Herrera, Neiras, Wanessa Christina de Souza, Alves, Renata Tomé, Rossit, Andréa Regina Baptista, Castilho, Lilian, Machado, Ricardo Luiz Dantas

“…We present evidence for Plasmodium vivax infection among Duffy blood group-negative inhabitants of Brazil. The P. vivax identification was determined by both…”
Get full text

Anti-Toxoplasma gondii antibodies in patients with beta-hemoglobinopathies: the first report in the Americas by Ferreira, Marina Neves, Bonini-Domingos, Claudia Regina, Fonseca Estevão, Isabeth, de Castro Lobo, Clarice Lopes, Souza Carrocini, Gisele Cristina, Silveira-Carvalho, Aparecida Perpétuo, Ricci, Jr, Octávio, de Mattos, Luiz Carlos, Brandão de Mattos, Cinara Cássia

“…In Brazil, there have been no previous studies of Toxoplasma gondii infection in sickle cell anemia patients and carriers of severe forms of beta-thalassemia…”
Get full text

Prevalence of βS-globin gene haplotypes, α-thalassemia (3.7 kb deletion) and redox status in patients with sickle cell anemia in the state of Paraná, Brazil by Shimauti, Eliana LitsukoTomimatsu, Silva, Danilo Grunig Humberto, Souza, Eniuce Menezes de, Almeida, Eduardo Alves de, Leal, Francismar Prestes, Bonini-Domingos, Claudia Regina

“…The aim of this study was to determine the frequency of beta S-globin gene (β S globin) haplotypes and alpha thalassemia with 3.7 kb deletion (−α 3.7kb…”
Get full text

Screening of Transcription Factors Involved in Fetal Hemoglobin Regulation Using Phylogenetic Footprinting by De Souza Carrocini, Gisele Cristine, Venancio, Larissa Paola Rodrigues, Bonini-Domingos, Claudia Regina

“…Fetal hemoglobin (Hb F) is an important genetic modulator of the beta-hemoglobinopathies. The regulation of Hb F levels is influenced by transcription factors…”
Get full text

The 844ins68 cystathionine beta-synthase and C677T MTHFR gene polymorphism and the vaso-occlusive event risk in sickle cell disease by Alves Jacob, Maza, da Cunha Bastos, Celso, Regina Bonini-Domingos, Claudia

“…Sickle cell disease (SCD) is an inflammatory condition with an increase in the adhesion of sickled erythrocytes, and it is a potential cause of vaso-occlusive…”
Get full text

O processo de consentimento livre e esclarecido nas pesquisas em doença falciforme by Valêncio, Luis Felipe Siqueira, Domingos, Claudia Regina Bonini

“…Resumo Doença falciforme diz respeito a grupo de hemoglobinopatias associadas à presença da hemoglobina S. Sendo majoritária na população negra, e acometendo…”
Get full text

Mixed Plasmodium falciparum infections and its clinical implications in four areas of the Brazilian Amazon region by Lorenzetti, Alexandre, Fornazari, Patrícia Aparecida, Bonini-Domingos, Ana Carolina, de Souza Rodrigues Penhalbel, Roberta, Fugikaha, Érika, Bonini-Domingos, Cláudia Regina, Fraga, Valéria Daltibari, Conceição, Luciana Moran, Rossit, Andréa Regina Baptista, Cavasini, Carlos Eugênio, Couto, Vanja Suely Calvosa D’Almeida, Machado, Ricardo Luiz Dantas

“…The aim of this study was to assess the prevalence pattern of mixed- Plasmodium falciparum malaria infections in Brazil by molecular diagnosis and to address…”
Get full text

Compound heterozygosity for hemoglobin S and D: what do we need to know? by Bonini-Domingos, Claudia Regina

Get full text

Molecular screening of Plasmodium sp. asymptomatic carriers among transfusion centers from brazilian amazon region by FUGIKAHA, Erica, FORNAZARI, Patricia Aparecida, ROSSIT, Andréa Regina Baptista, CAVASINI, Carlos Eugenio, MACHADO, Ricardo Luiz Dantas, PENHALBEL, Roberta De Souza Rodrigues, LORENZETTI, Alexandre, MAROSO, Roberto Duarte, AMORAS, Juvanete Tavora, SARAIVA, Ana Sueli, DA SILVA, Rita Uchoa, BONINI-DOMINGOS, Claudia Regina, DE MATTOS, Luiz Carlos

“…The transmission of malaria in Brazil is heterogeneous throughout endemic areas and the presence of asymptomatic Plasmodium sp. carriers (APCs) in the…”
Get full text

Hemoglobin D-Punjab: origin, distribution and laboratory diagnosis by Torres, Lidiane de Souza, Okumura, Jéssika Viviani, Silva, Danilo Grünig Humberto da, Bonini-Domingos, Claudia Regina

“…This review discusses hemoglobin D-Punjab, also known as hemoglobin D-Los Angeles, one of the most common hemoglobin variants worldwide. It is derived from a…”
Get full text

Oxidative stress in sickle cell disease: An overview of erythrocyte redox metabolism and current antioxidant therapeutic strategies by Silva, Danilo Grunig Humberto, Belini Junior, Edis, de Almeida, Eduardo Alves, Bonini-Domingos, Claudia Regina

“…Erythrocytes have an environment of continuous pro-oxidant generation due to the presence of hemoglobin (Hb), which represents an additional and quantitatively…”
Get full text

The Cs a and Cs b Red Cell Antigens of the Cost Blood Group Collection Correspond to the HNA-3a and HNA-3b Neutrophil Antigens: Unexpected Twins with Implications for Sickle Cell Anemia by De Oliveira Rios, Jonathan, Soudry, Alisa, Duval, Romain, Raneri, Alexandre, Poyot, Thomas, Babinet, Jérome, De Montalembert, Mariane, Regina Bonini Domingos, Claudia, Le Van Kim, Caroline, Romana, Marc, Peyrard, Thierry, Azouzi, Slim

“…Recent genome-wide association and murine studies identified the human neutrophil antigen 3a/b polymorphism (HNA-3a/b) in SLC44A2 (rs2288904-G/A) as a risk…”
Get full text

P-212 - Influence of hemoglobin S on metabolic homeostasis of human erythrocytes – partial results by Chaves, Nayara Alves, Humberto da Silva, Danilo Grünig, Domingos, Claudia Regina Bonini

“…This is an initial study regarding the influence of redox imbalance of sickle cells on erythrocyte metabolism. Thus, the study is carrying out on ten patients…”
Get full text