Search Results - "Dominah, Gifty"

Taking a Bite Out of Amyloid: Mechanistic Insights into α‑Synuclein Degradation by Cathepsin L by McGlinchey, Ryan P, Dominah, Gifty A, Lee, Jennifer C

“…A common hallmark of amyloids is their resistance to an array of proteases, highlighting the difficulty in degrading these disease-related aggregated…”
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Acute exposure to chlorpyrifos caused NADPH oxidase mediated oxidative stress and neurotoxicity in a striatal cell model of Huntington’s disease by Dominah, Gifty A., McMinimy, Rachael A., Kallon, Sallay, Kwakye, Gunnar F.

“…Model for mutant Huntingtin (HTT) and chlorpyrifos (CPF)-induced oxidative stress in HD striatal cells. Expression of mutant HTT exacerbates CPF-induced…”
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GL261 luciferase-expressing cells elicit an anti-tumor immune response: an evaluation of murine glioma models by Sanchez, Victoria E., Lynes, John P., Walbridge, Stuart, Wang, Xiang, Edwards, Nancy A., Nwankwo, Anthony K., Sur, Hannah P., Dominah, Gifty A., Obungu, Arnold, Adamstein, Nicholas, Dagur, Pradeep K., Maric, Dragan, Munasinghe, Jeeva, Heiss, John D., Nduom, Edjah K.

“…Preclinical models that reliably recapitulate the immunosuppressive properties of human gliomas are essential to assess immune-based therapies. GL261 murine…”
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Current Options and Future Directions in Immune Therapy for Glioblastoma by Lynes, John, Sanchez, Victoria, Dominah, Gifty, Nwankwo, Anthony, Nduom, Edjah

“…Glioblastoma is in need of innovative treatment approaches. Immune therapy for cancer refers to the use of the body's immune system to target malignant cells…”
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Author Correction: GL261 luciferase-expressing cells elicit an anti-tumor immune response: an evaluation of murine glioma models by Sanchez, Victoria E., Lynes, John P., Walbridge, Stuart, Wang, Xiang, Edwards, Nancy A., Nwankwo, Anthony K., Sur, Hannah P., Dominah, Gifty A., Obungu, Arnold, Adamstein, Nicholas, Dagur, Pradeep K., Maric, Dragan, Munasinghe, Jeeva, Heiss, John D., Nduom, Edjah K.

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Biomarkers for immunotherapy for treatment of glioblastoma by Lynes, John P, Nwankwo, Anthony K, Sur, Hannah P, Sanchez, Victoria E, Sarpong, Kwadwo A, Ariyo, Oluwatobi I, Dominah, Gifty A, Nduom, Edjah K

“…Immunotherapy is a promising new therapeutic field that has demonstrated significant benefits in many solid-tumor malignancies, such as metastatic melanoma and…”
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Fatty acid oxidation contributes to IL-1β secretion in M2 macrophages and promotes macrophage-mediated tumor cell migration by Zhang, Qi, Wang, Herui, Mao, Chengyuan, Sun, Mitchell, Dominah, Gifty, Chen, Liyuan, Zhuang, Zhengping

“…•Fatty acid oxidation rather than other energy sources supports M2 polarized macrophages-mediated enhancement of tumor cell migration.•M2 polarized macrophages…”
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Immune checkpoint modulation: Tenets and implications in glioblastoma by Lynes, John, Sanchez, Victoria, Nwankwo, Anthony, Dominah, Gifty, Nduom, Edjah

“…Glioblastoma (GBM) is the most common primary central nervous system tumor, and despite advances made in traditional chemotherapy and radiation, it continues…”
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EVALUATING APACHE AND SOFA SCORING SYSTEMS IN PATIENTS WITH COVID-19 by GOWDA, NIRAJ, DOMINAH, GIFTY, ROGERS, HAYLEY, ELSHIKH, AMIRA, GOWDA, SURAJ, BENJENK, IVY, YAMANE, DAVID

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A Chronic Obstructive Pulmonary Disease Exacerbation Following the Administration of a COVID 19-Booster Vaccine: A Case Report by Gatenby, William, Dominah, Gifty, Paudel, Amrit, Saleh, Nahar

“…We present a case of a patient who presented to the emergency department with symptoms suggestive of a chronic obstructive pulmonary disease (COPD)…”
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Programmed Death Ligand 1 Is a Negative Prognostic Marker in Recurrent Isocitrate Dehydrogenase-Wildtype Glioblastoma by Pratt, Drew, Dominah, Gifty, Lobel, Graham, Obungu, Arnold, Lynes, John, Sanchez, Victoria, Adamstein, Nicholas, Wang, Xiang, Edwards, Nancy A, Wu, Tianxia, Maric, Dragan, Giles, Amber J, Gilbert, Mark R, Quezado, Martha, Nduom, Edjah K

“…Checkpoint inhibition has demonstrated clinical efficacy in a variety of solid tumors. Reports of programmed death ligand 1 (PD-L1) expression in glioblastoma…”
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TMOD-05. GLIOMA-261 LUCIFERASE-EXPRESSING CELL LINE STIMULATES AN IMMUNOGENIC RESPONSE SIGNATURE IN AN IMMUNOCOMPETENT MURINE MODEL by Sanchez, Victoria, Lynes, John, Dominah, Gifty, Wang, Xiang, Obungu, Arnold, Walbridge, Stuart, Edwards, Nancy, Nduom, Edjah

“…Abstract Immunocompetent murine models of glioma, such as GL261, are essential to assess immune therapy efficacy. The GL261 cell line expressing firefly…”
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Peritoneal Amyloidosis as a Presenting Manifestation of AL Amyloid by Acharya, Indira, Dominah, Gifty A., Xing, Dongmei, Allen, Elizabeth, Iding, Jeffrey S., Haas, Christopher J.

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Peritoneal Amyloid as a Presenting Manifestation of AL Amyloid by Acharya, Indira, Dominah, Gifty A., Xing, Dongmei, Allen, Elizabeth, Iding, Jeffrey S., Haas, Christopher J.

“…Amyloid is a systemic disease characterized by extracellular deposition of misfolded protein. Gastrointestinal and peritoneal deposition of light chain (AL)…”
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Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade by Lynes, John, Jackson, Sadhana, Sanchez, Victoria, Dominah, Gifty, Wang, Xiang, Kuek, Averie, Hayes, Christina Piper, Benzo, Sarah, Scott, Gretchen C, Chittiboina, Prashant, Zaghloul, Kareem A, Park, Deric M, Wu, Jing, Hourigan, Christopher S, Giles, Amber J, Wu, Tianxia, Maric, Dragan, Chen, Jinguo, Quezado, Martha, Heiss, John D, Gilbert, Mark R, Nduom, Edjah K

“…Abstract BACKGROUND Glioblastoma is the most common primary malignancy of the brain, with a dismal prognosis. Immunomodulation via checkpoint inhibition has…”
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TMIC-28. LONG NON-CODING RNA EXPRESSION DIFFERS BETWEEN GLIOBLASTOMA PATIENT IMMUNE CELLS AND HEALTHY VOLUNTEERS by Nwankwo, Anthony, Sanchez, Victoria, Lynes, John, Wang, Xiang, Dominah, Gifty, Obungu, Arnold, Edwards, Nancy, Sarpong, Kwadwo, Ariyo, Oluwatobi, Johnson, Kory, K Nduom, Edjah

“…Abstract To improve glioblastoma treatment, improved characterization of the tumor’s immune microenvironment is critical. Aberrant long non-coding RNA (LncRNA)…”
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The Luciferase-Expressing Glioma-261 Murine Models Elicit an Immune-Mediated Antitumor Response by Sanchez, Victoria E, Lynes, John, Walbridge, Stuart, Wang, Xiang, Edwards, Nancy A, Nwankwo, Anthony, Dominah, Gifty, Obungu, Arnold, Adamstein, Nicholas, Dagur, Pradeep, Wu, Tianxia, Maric, Dragan, Heiss, John D, Nduom, Edjah K

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Enhancement of mitochondrial biogenesis and paradoxical inhibition of lactate dehydrogenase mediated by 14‐3‐3η in oncocytomas by Feng, Jie, Zhang, Qi, Li, Chuzhong, Zhou, Yang, Zhao, Sida, Hong, Lichuan, Song, Qi, Yu, Shenyuan, Hu, Chunxiu, Wang, Herui, Mao, Chengyuan, Shepard, Matthew J, Hao, Shuyu, Dominah, Gifty, Sun, Mitchell, Wan, Hong, Park, Deric M, Gilbert, Mark R, Xu, Guowang, Zhuang, Zhengping, Zhang, Yazhuo

“…Oncocytomas represent a subset of benign pituitary adenomas that are characterized by significant mitochondrial hyperplasia. Mitochondria are key organelles…”
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TMOD-32. GL261 LUCIFERASE-EXPRESSING CELLS ELICIT AN ANTI-TUMOR IMMUNE RESPONSE: AN EVALUATION OF MURINE GLIOMA MODELS by Sanchez, Victoria, Lynes, John, Walbridge, Stuart, Wang, Xiang, Edwards, Nancy, Nwankwo, Anthony, Dominah, Gifty, Obungu, Arnold, Adamstein, Nicholas, Dagur, Pradeep, Wu, Tianxia, Maric, Dragan, Munasinghe, Jeeva, Heiss, John, K Nduom, Edjah

“…Abstract Preclinical models that reliably recapitulate the immunosuppressive properties of human gliomas are essential to assess immune-based therapies…”
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IMMU-02. VALIDATION OF PD-L1 EXPRESSION IN HIGH GRADE GLIOMAS AS AN INDEPENDENT NEGATIVE PROGNOSTIC MARKER by Pratt, Drew, Dominah, Gifty, Lobel, Graham, Obungu, Arnold, Wang, Xiang, Edwards, Nancy A, Maric, Dragan, Gilbert, Mark R, Quezado, Martha, Nduom, Edjah K

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