Search Results - "Domb, A J"

Chitosan Chemistry and Pharmaceutical Perspectives by Kumar, M. N. V. Ravi, Muzzarelli, R. A. A, Muzzarelli, C, Sashiwa, H, Domb, A. J

“…Chitosan is a safe and friendly substance for the human organism. Kumar et al provide interdisciplinary insight in the scientific knowledge immediately usable…”
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From hydroxychloroquine to ivermectin: what are the anti-viral properties of anti-parasitic drugs to combat SARS-CoV-2? by Rakedzon, S, Neuberger, A, Domb, A J, Petersiel, N, Schwartz, E

“…Abstract Background Nearly a year into the COVID-19 pandemic, we still lack effective anti-SARS-CoV-2 drugs with substantial impact on mortality rates except…”
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Polymers for DNA delivery by Eliyahu, H, Barenholz, Y, Domb, A J

“…Nucleic acid delivery has many applications in basic science, biotechnology, agriculture, and medicine. One of the main applications is DNA or RNA delivery for…”
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Role of polyanhydrides as localized drug carriers by Jain, Jay Prakash, Modi, Sweta, Domb, A.J., Kumar, Neeraj

“…Many drugs that are administered in an unmodified form by conventional systemic routes fail to reach target organs in an effective concentration, or are not…”
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Extended release formulations for local anaesthetic agents by Weiniger, C. F., Golovanevski, L., Domb, A. J., Ickowicz, D.

“…Summary Systemic toxicity through overdose of local anaesthetic agents is a real concern. By encapsulating local anaesthetics in biodegradable carriers to…”
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Dextran-spermine polycation: an efficient nonviral vector for in vitro and in vivo gene transfection by HOSSEINKHANI, H, AZZAM, T, TABATA, Y, DOMB, A. J

“…Dextran-spermine cationic polysaccharide was prepared by means of reductive amination between oxidized dextran and the natural oligoamine spermine. The formed…”
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Lipoplex-induced hemagglutination: potential involvement in intravenous gene delivery by ELIYAHU, H, SERVEL, N, DOMB, A. J, BARENHOLZ, Y

“…We report a study aiming to characterize the interaction of blood and blood components with lipoplexes under conditions relevant to in vivo intravenous…”
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Novel dextran-spermine conjugates as transfecting agents: comparing water-soluble and micellar polymers by ELIYAHU, H, MAKOVITZKI, A, AZZAM, T, ZLOTKIN, A, JOSEPH, A, GAZIT, D, BARENHOLZ, Y, DOMB, A. J

“…Recently, a novel cationic polymer, dextran-spermine (D-SPM) was developed for gene delivery. An efficient transfection was obtained using this polycation for…”
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Dynamics of PEGylated–Dextran–Spermine Nanoparticles for Gene Delivery to Leukemic Cells by Amini, R., Jalilian, F. Azizi, Abdullah, S., Veerakumarasivam, A., Hosseinkhani, H., Abdulamir, A. S., Domb, A. J., Ickowicz, D., Rosli, R.

“…Leukemic cells are hard-to-transfect cell lines. Many transfection reagents which can provide high gene transfer efficiency in common adherent cell lines are…”
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Biodegradable block copolymers by Kumar, Neeraj, Ravikumar, Majeti N.V., Domb, A.J.

“…Recently, block copolymers have got tremendous impetus on the ongoing research in the area of drug delivery technology, due to their capability to provide a…”
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Review of prolonged local anesthetic action by Weiniger, Carolyn F, Golovanevski, M, Sokolsky-Papkov, M, Domb, A J

“…Pain following surgery is often treated by local anesthetic agents. Duration of the analgesia can be extended safely following administration of encapsulated…”
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Exploiting EPR in polymer drug conjugate delivery for tumor targeting by Modi, Sweta, Prakash Jain, Jay, Domb, A J, Kumar, Neeraj

“…Treatment of tumor tissue without affecting normal cells has always been formidable task for drug delivery scientists and this task is effectively executed by…”
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Preparation and in vitro characterization of poly(sebacic acid-co-ricinoleic acid)-based tamoxifen citrate-loaded microparticles for breast cancer by Hiremath, J. G., Rudani, C.G., Domb, A. J., Suthar, R. V., Khamar, N. S.

“…This study was aimed to develop an injectable polymeric drug delivery system for tamoxifen citrate (TC) using poly(sebacic acid‐co‐ricinoleic acid)…”
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Biodegradable poly(sebacic acid-co-ricinoleic-ester anhydride) tamoxifen citrate implants: Preparation and in vitro characterization by Hiremath, J.G, Kusum Devi, V, Devi, Kshama, Domb, A.J

“…The aim of this study was to prepare tamoxifen citrate loaded cylindrical polymeric implants for application at tumor sites. The implant was based on poly…”
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Copolymers of pharmaceutical grade lactic acid and sebacic acid: Drug release behavior and biocompatibility by Modi, Sweta, Jain, Jay Prakash, Domb, A.J., Kumar, Neeraj

“…Pharmaceutical grade d, l-lactic acid, which is rather an economic source in comparison to lactide monomer, was utilized for synthesis of a series of…”
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Stereocomplexes based on poly(lactic acid) and insulin: formulation and release studies by Slager, J, Domb, A.J

“…Diastereoisomeric complexes of insulin with d-poly(lactic acid) ( d-PLA) or stereocomplexes of d- and l-PLA entrapping insulin were discovered. The complexes…”
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Biocompatibility of a Polymeric Implant for the Treatment of Osteomyelitis by Brin, Y. S., Nyska, A., Domb, A. J., Golenser, J., Mizrahi, B., Nyska, M.

“…We evaluated the biocompatibility of an injectable gelling polymeric device for the controlled release of gentamicin sulfate in the treatment of invasive…”
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Tamoxifen citrate loaded biodegradable poly(sebacic acid-co- ricinoleic acid) microparticles, in vitro characterization by Hiremath, J.G., Rudani, C.G., Suthar, R.V., Domb, A.J.

“…The aim of the present investigation was to develop biodegradable microparticles of the antineoplastic drug, tamoxifen citrate, for the treatment of breast…”
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Synthesis and characterization of novel water soluble amphotericin B–arabinogalactan conjugates by Ehrenfreund-Kleinman, T, Azzam, T, Falk, R, Polacheck, I, Golenser, J, Domb, A.J

“…The coupling of amphotericin B (AmB), a water-insoluble antifungal agent, to arabinogalactan (AG) via an imine or amine bond was systematically investigated…”
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Conjugation of amino-containing drugs to polysaccharides by tosylation: amphotericin B–arabinogalactan conjugates by Ehrenfreund-Kleinman, Tirsta, Golenser, Jacob, Domb, Abraham J

“…The coupling of amphotericin-B (AmB), a water-insoluble antifungal and antileishmanial agent, to arabinogalactan (AG) via tosylate or mesylate derivatives was…”
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