Search Results - "Domaschenz, Renae"
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Multiple roles of H2A.Z in regulating promoter chromatin architecture in human cells
Published in Nature communications (05-05-2021)“…Chromatin accessibility of a promoter is fundamental in regulating transcriptional activity. The histone variant H2A.Z has been shown to contribute to this…”
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The Histone Variant H2A.Z Is a Master Regulator of the Epithelial-Mesenchymal Transition
Published in Cell reports (Cambridge) (24-10-2017)“…Epithelial-mesenchymal transition (EMT) is a profound example of cell plasticity that is crucial for embryonic development and cancer. Although it has long…”
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Epigenetic Priming of a Pre-B Cell-Specific Enhancer through Binding of Sox2 and Foxd3 at the ESC Stage
Published in Cell stem cell (02-07-2010)“…Modifications to the core histones are thought to contribute to ESC pluripotency by priming tissue-specific promoters and enhancers for later activation…”
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Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells
Published in Genes & development (15-07-2005)“…The intestinal epithelium comprises differentiated cells of four lineages maintained by precursor cells. As the Notch pathway controls the fate of…”
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Comparative epigenomics: an emerging field with breakthrough potential to understand evolution of epigenetic regulation
Published in AIMS genetics (01-12-2014)“…Abstract Epigenetic mechanisms regulate gene expression, thereby mediating the interaction between environment, genotype and phenotype. Changes to epigenetic…”
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Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia
Published in Oncotarget (04-10-2016)“…Ikaros and Foxp1 are transcription factors that play key roles in normal lymphopoiesis and lymphoid malignancies. We describe a novel physical and functional…”
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Identification of interleukin genes in Pogona vitticeps using a de novo transcriptome assembly from RNA-seq data
Published in Immunogenetics (New York) (01-10-2016)“…Interleukins are a group of cytokines with complex immunomodulatory functions that are important for regulating immunity in vertebrate species. Reptiles and…”
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Immunofluorescent staining reveals hypermethylation of microchromosomes in the central bearded dragon, Pogona vitticeps
Published in Molecular cytogenetics (30-12-2015)“…Studies of model organisms have demonstrated that DNA cytosine methylation and histone modifications are key regulators of gene expression in biological…”
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Hes6 is required for actin cytoskeletal organization in differentiating C2C12 myoblasts
Published in Experimental cell research (01-07-2011)“…Hes6 is a member of the hairy-enhancer-of-split family of transcription factors that regulate proliferating cell fate in development and is known to be…”
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HES6 enhances the motility of alveolar rhabdomyosarcoma cells
Published in Experimental cell research (01-01-2013)“…HES6, a member of the hairy-enhancer-of-split family of transcription factors, plays multiple roles in myogenesis. It is a direct target of the myogenic…”
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Exercise-Induced Tendon and Bone Injury in Recreational Runners: A Test-Retest Reliability Study
Published in JMIR research protocols (07-10-2015)“…Background: Long-distance runners are prone to injuries including Achilles tendinopathy and medial tibial stress syndrome. We have developed an Internet…”
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