Search Results - "Doménech, Guillermo"

Axonal autophagosome maturation defect through failure of ATG9A sorting underpins pathology in AP-4 deficiency syndrome by Ivankovic, Davor, Drew, James, Lesept, Flavie, White, Ian J., López Doménech, Guillermo, Tooze, Sharon A., Kittler, Josef T.

“…Adaptor protein (AP) complexes mediate key sorting decisions in the cell through selective incorporation of transmembrane proteins into vesicles. Little is…”
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Tomato Juice Supplementation Influences the Gene Expression Related to Steatosis in Rats by Elvira-Torales, Laura Inés, Navarro-González, Inmaculada, González-Barrio, Rocío, Martín-Pozuelo, Gala, Doménech, Guillermo, Seva, Juan, García-Alonso, Javier, Periago-Castón, María Jesús

“…The objective of this work was to identify the effect of tomato juice on the expression of genes and levels of metabolites related to steatosis in rats. Male…”
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Cross-sectional study to evaluate the associated factors with differences between city and districts secondary school students of the southeast of Spain (Murcia) for their adherence to the Mediterranean diet by Doménech-Asensi, Guillermo, Sánchez-Martínez, Álvaro, Ros-Berruezo, Gaspar

“…The "Mediterranean diet" is recognized as one of the healthiest dietary patterns but, even in Mediterranean countries it is gradually being lost. Adolescence…”
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Otodectes cynotis in urban and peri-urban semi-arid areas: a widespread parasite in the cat population by Fanelli, Angela, Doménech, Guillermo, Alonso, Francisco, Martínez-Carrasco, Federico, Tizzani, Paolo, Martínez-Carrasco, Carlos

“…The ear mite Otodectes cynotis is a parasite of cats and dogs of considerable veterinary importance, being the most common etiological agent of otitis externa…”
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Miro proteins coordinate microtubule‐ and actin‐dependent mitochondrial transport and distribution by López‐Doménech, Guillermo, Covill‐Cooke, Christian, Ivankovic, Davor, Halff, Els F, Sheehan, David F, Norkett, Rosalind, Birsa, Nicol, Kittler, Josef T

“…In the current model of mitochondrial trafficking, Miro1 and Miro2 Rho‐GTPases regulate mitochondrial transport along microtubules by linking mitochondria to…”
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Adherence to the Mediterranean diet by nursing students of Murcia (Spain) by Navarro-González, Inmaculada, López-Nicolás, Rubén, Rodríguez-Tadeo, Alejandra, Ros-Berruezo, Gaspar, Martínez-Marín, Mariano, Doménech-Asensi, Guillermo

“…The Mediterranean diet is recognized as one with the healthiest dietary patterns; however, this diet is deteriorating and being abandoned even in the…”
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An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors by Davenport, Elizabeth C., Pendolino, Valentina, Kontou, Georgina, McGee, Thomas P., Sheehan, David F., López-Doménech, Guillermo, Farrant, Mark, Kittler, Josef T.

“…Inhibitory synaptic transmission requires the targeting and stabilization of GABAA receptors (GABAARs) at synapses. The mechanisms responsible remain poorly…”
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Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response by López‐Doménech, Guillermo, Howden, Jack H, Covill‐Cooke, Christian, Morfill, Corinne, Patel, Jigna V, Bürli, Roland, Crowther, Damian, Birsa, Nicol, Brandon, Nicholas J, Kittler, Josef T

“…Clearance of mitochondria following damage is critical for neuronal homeostasis. Here, we investigate the role of Miro proteins in mitochondrial turnover by…”
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Mitochondrial regulation of local supply of energy in neurons by López-Doménech, Guillermo, Kittler, Josef T.

“…Brain computation is metabolically expensive and requires the supply of significant amounts of energy. Mitochondria are highly specialized organelles whose…”
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Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery by Modi, Souvik, López-Doménech, Guillermo, Halff, Elise F., Covill-Cooke, Christian, Ivankovic, Davor, Melandri, Daniela, Arancibia-Cárcamo, I. Lorena, Burden, Jemima J., Lowe, Alan R., Kittler, Josef T.

“…Mitochondrial Rho (Miro) GTPases localize to the outer mitochondrial membrane and are essential machinery for the regulated trafficking of mitochondria to…”
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Peroxisomal fission is modulated by the mitochondrial Rho‐GTPases, Miro1 and Miro2 by Covill‐Cooke, Christian, Toncheva, Viktoriya S, Drew, James, Birsa, Nicol, López‐Doménech, Guillermo, Kittler, Josef T

“…Peroxisomes are essential for a number of cellular functions, including reactive oxygen species metabolism, fatty acid β‐oxidation and lipid synthesis. To…”
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Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition by Davenport, Elizabeth C., Szulc, Blanka R., Drew, James, Taylor, James, Morgan, Toby, Higgs, Nathalie F., López-Doménech, Guillermo, Kittler, Josef T.

“…Altered excitatory/inhibitory (E/I) balance is implicated in neuropsychiatric and neurodevelopmental disorders, but the underlying genetic etiology remains…”
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Miro1 Regulates Activity-Driven Positioning of Mitochondria within Astrocytic Processes Apposed to Synapses to Regulate Intracellular Calcium Signaling by Stephen, Terri-Leigh, Higgs, Nathalie F, Sheehan, David F, Al Awabdh, Sana, López-Doménech, Guillermo, Arancibia-Carcamo, I Lorena, Kittler, Josef T

“…It is fast emerging that maintaining mitochondrial function is important for regulating astrocyte function, although the specific mechanisms that govern…”
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Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites by López-Doménech, Guillermo, Higgs, Nathalie F., Vaccaro, Victoria, Roš, Hana, Arancibia-Cárcamo, I. Lorena, MacAskill, Andrew F., Kittler, Josef T.

“…Correct mitochondrial distribution is critical for satisfying local energy demands and calcium buffering requirements and supporting key cellular processes…”
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An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABA A Receptors by Davenport, Elizabeth C, Pendolino, Valentina, Kontou, Georgina, McGee, Thomas P, Sheehan, David F, López-Doménech, Guillermo, Farrant, Mark, Kittler, Josef T

“…Inhibitory synaptic transmission requires the targeting and stabilization of GABA receptors (GABA Rs) at synapses. The mechanisms responsible remain poorly…”
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Mitochondrial Ca2+ uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses by Devine, Michael J, Szulc, Blanka R, Howden, Jack H, López-Doménech, Guillermo, Ruiz, Arnaud, Kittler, Josef T

“…Long-term changes in synaptic strength form the basis of learning and memory. These changes rely upon energy-demanding mechanisms, which are regulated by local…”
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Moringa oleifera: Revisión sobre aplicaciones y usos en alimentos by Guillermo Doménech Asensi, Alba Manuela Durango Villadiego, Gaspar, Ros Berruezo

“…Moringa oleifera is a tree native to certain regions Asia and Africa, adaptable to territories of hot weather and low precipitation rates. In some areas…”
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Shared structural features of Miro binding control mitochondrial homeostasis by Covill-Cooke, Christian, Kwizera, Brian, López-Doménech, Guillermo, Thompson, Caleb OD, Cheung, Ngaam J, Cerezo, Ema, Peterka, Martin, Kittler, Josef T, Kornmann, Benoît

“…Miro proteins are universally conserved mitochondrial calcium-binding GTPases that regulate a multitude of mitochondrial processes, including transport,…”
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GSK3β is involved in the relief of mitochondria pausing in a Tau-dependent manner by Llorens-Martín, María, López-Doménech, Guillermo, Soriano, Eduardo, Avila, Jesús

“…Mitochondrial trafficking deficits have been implicated in the pathogenesis of several neurological diseases, including Alzheimer's disease (AD). The Ser/Thre…”
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Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation by Vitureira, Nathalia, Andrés, Rosa, Pérez-Martínez, Esther, Martínez, Albert, Bribián, Ana, Blasi, Juan, Chelliah, Shierley, López-Doménech, Guillermo, De Castro, Fernando, Burgaya, Ferran, McNagny, Kelly, Soriano, Eduardo

“…Neural development and plasticity are regulated by neural adhesion proteins, including the polysialylated form of NCAM (PSA-NCAM). Podocalyxin (PC) is a renal…”
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