Search Results - "Dom, Geneviève"

Understanding the Dosage-Dependent Role of Dicer1 in Thyroid Tumorigenesis by Rojo-Pardillo, María, Godefroid, Ludivine, Dom, Geneviève, Lefort, Anne, Libert, Frederick, Robaye, Bernard, Maenhaut, Carine

“…Tumors originating from thyroid follicular cells are the most common endocrine tumors, with rising incidence. Despite a generally good prognosis, up to 20% of…”
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mRNA expression in papillary and anaplastic thyroid carcinoma: molecular anatomy of a killing switch by Hébrant, Aline, Dom, Geneviève, Dewaele, Michael, Andry, Guy, Trésallet, Christophe, Leteurtre, Emmanuelle, Dumont, Jacques E, Maenhaut, Carine

“…Anaplastic thyroid carcinoma (ATC) is the most lethal form of thyroid neoplasia and represents the end stage of thyroid tumor progression. No effective…”
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CDK4 phosphorylation status and rational use for combining CDK4/6 and BRAF/MEK inhibition in advanced thyroid carcinomas by Pita, Jaime M, Raspé, Eric, Coulonval, Katia, Decaussin-Petrucci, Myriam, Tarabichi, Maxime, Dom, Geneviève, Libert, Frederick, Craciun, Ligia, Andry, Guy, Wicquart, Laurence, Leteurtre, Emmanuelle, Trésallet, Christophe, Marlow, Laura A, Copland, John A, Durante, Cosimo, Maenhaut, Carine, Cavaco, Branca M, Dumont, Jacques E, Costante, Giuseppe, Roger, Pierre P

“…CDK4/6 inhibitors (CDK4/6i) have been established as standard treatment against advanced Estrogen Receptor-positive breast cancers. These drugs are being…”
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Transcriptomic Signature of Human Embryonic Thyroid Reveals Transition From Differentiation to Functional Maturation by Dom, Geneviève, Dmitriev, Petr, Lambot, Marie-Alexandra, Van Vliet, Guy, Glinoer, Daniel, Libert, Frédérick, Lefort, Anne, Dumont, Jacques E., Maenhaut, Carine

“…The human thyroid gland acquires a differentiation program as early as weeks 3–4 of embryonic development. The onset of functional differentiation, which…”
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Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells by Nielsen, Rikke, Courtoy, Pierre J, Jacobsen, Christian, Dom, Geneviève, Lima, Wânia Rezende, Jadot, Michel, Willnow, Thomas E, Devuyst, Olivier, Christensen, Erik I

“…Recruitment of acid hydrolases to lysosomes generally occurs by intracellular sorting based on recognition of a common mannose 6-phosphate signal in the…”
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Loss of Chloride Channel ClC-5 Impairs Endocytosis by Defective Trafficking of Megalin and Cubilin in Kidney Proximal Tubules by Christensen, Erik I., Devuyst, Olivier, Dom, Geneviève, Nielsen, Rikke, Van Der Smissen, Patrick, Verroust, Pierre, Leruth, Michèle, Guggino, William B., Courtoy, Pierre J.

“…Loss of the renal endosome-associated chloride channel, ClC-5, in Dent's disease and knockout (KO) mice strongly inhibits endocytosis of filtered proteins by…”
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Cellular uptake of Antennapedia Penetratin peptides is a two‐step process in which phase transfer precedes a tryptophan‐dependent translocation by Dom, Geneviève, Shaw‐Jackson, Chloë, Matis, Christelle, Bouffioux, Olivier, Picard, Jacques J., Prochiantz, Alain, Mingeot‐Leclercq, Marie‐Paule, Brasseur, Robert, Rezsohazy, René

“…Several homeodomains and homeodomain‐containing proteins enter live cells through a receptor‐ and energy‐independent mechanism. Translocation through…”
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Dynamic Cancer Cell Heterogeneity: Diagnostic and Therapeutic Implications by Jacquemin, Valerie, Antoine, Mathieu, Dom, Geneviève, Detours, Vincent, Maenhaut, Carine, Dumont, Jacques E

“…Though heterogeneity of cancers is recognized and has been much discussed in recent years, the concept often remains overlooked in different routine…”
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Gene signature of the post-Chernobyl papillary thyroid cancer by Handkiewicz-Junak, Daria, Swierniak, Michal, Rusinek, Dagmara, Oczko-Wojciechowska, Małgorzata, Dom, Genevieve, Maenhaut, Carine, Unger, Kristian, Detours, Vincent, Bogdanova, Tetiana, Thomas, Geraldine, Likhtarov, Ilya, Jaksik, Roman, Kowalska, Malgorzata, Chmielik, Ewa, Jarzab, Michal, Swierniak, Andrzej, Jarzab, Barbara

“…Purpose Following the nuclear accidents in Chernobyl and later in Fukushima, the nuclear community has been faced with important issues concerning how to…”
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miRNA expression and function in thyroid carcinomas: a comparative and critical analysis and a model for other cancers by Saiselet, Manuel, Pita, Jaime M, Augenlicht, Alice, Dom, Geneviève, Tarabichi, Maxime, Fimereli, Danai, Dumont, Jacques E, Detours, Vincent, Maenhaut, Carine

“…As in many cancer types, miRNA expression profiles and functions have become an important field of research on non-medullary thyroid carcinomas, the most…”
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Cystic fibrosis is associated with a defect in apical receptor-mediated endocytosis in mouse and human kidney by JOURET, Francois, BERNARD, Alfred, COURTOY, Pierre J, DEVUYST, Olivier, HERMANS, Cédric, DOM, Geneviève, TERRYN, Sara, LEAL, Teresinha, LEBECQUE, Patrick, CASSIMAN, Jean-Jacques, SCHOLTE, Bob J, DE JONGE, Hugo R

“…Inactivation of the chloride channel cystic fibrosis transmembrane conductance regulator (CFTR) causes cystic fibrosis (CF). Although CFTR is expressed in the…”
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The boosting of didanosine by allopurinol permits a halving of the didanosine dosage by BOELAERT, Johan R, DOM, Geneviève M, HUITEMA, Alwin D. R, BEIJNEN, Jos H, LANGE, Joep M. A

“…The pharmacokinetic boosting of didanosine by allopurinol was studied in four HIV-1-positive patients taking didanosine, hydroxyurea and chloroquine, in whom…”
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5-aza-2'-deoxycytidine has minor effects on differentiation in human thyroid cancer cell lines, but modulates genes that are involved in adaptation in vitro by Dom, Geneviève, Galdo, Vanessa Chico, Tarabichi, Maxime, Tomás, Gil, Hébrant, Aline, Andry, Guy, De Martelar, Viviane, Libert, Frédérick, Leteurtre, Emmanuelle, Dumont, Jacques E, Maenhaut, Carine, van Staveren, Wilma C G

“…In thyroid cancer, the lack of response to specific treatment, for example, radioactive iodine, can be caused by a loss of differentiation characteristics of…”
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Role of Epac and protein kinase A in thyrotropin-induced gene expression in primary thyrocytes by van Staveren, Wilma C.G., Beeckman, Sandrine, Tomás, Gil, Dom, Geneviève, Hébrant, Aline, Delys, Laurent, Vliem, Marjolein J., Trésallet, Christophe, Andry, Guy, Franc, Brigitte, Libert, Frédérick, Dumont, Jacques E., Maenhaut, Carine

“…cAMP pathway activation by thyrotropin (TSH) induces differentiation and gene expression in thyrocytes. We investigated which partners of the cAMP cascade…”
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Thyroid cancer cell lines: an overview by Saiselet, Manuel, Floor, Sébastien, Tarabichi, Maxime, Dom, Geneviève, Hébrant, Aline, van Staveren, Wilma C G, Maenhaut, Carine

“…Human thyroid cancer cell lines are the most used models for thyroid cancer studies. They must be used with detailed knowledge of their characteristics. These…”
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Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution by Dom, Geneviève, Frank, Sandra, Floor, Sebastien, Kehagias, Pashalina, Libert, Frederick, Hoang, Catherine, Andry, Guy, Spinette, Alex, Craciun, Ligia, de Saint Aubin, Nicolas, Tresallet, Christophe, Tissier, Frederique, Savagner, Frederique, Majjaj, Samira, Gutierrez-Roelens, Ilse, Marbaix, Etienne, Dumont, Jacques E, Maenhaut, Carine

“…Non-autonomous thyroid nodules are common in the general population with a proportion found to be cancerous. A current challenge in the field is to be able to…”
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Cancer stem cells, a fuzzy evolving concept: A cell population or a cell property? by Antoniou, Aline, Hébrant, Aline, Dom, Genevieve, Dumont, Jacques, Maenhaut, Carine

“…The cancer stem cells (CSC) hypothesis represents a pathological extrapolation of the physiological concept of embryonic and somatic stem cells. In its initial…”
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Loss of chloride channel CIC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules by Christensen, Erik I, Devuyst, Olivier, Dom, Genevieve, Nielsen, Rikke

“…Loss of the renal endosome-associated chloride channel, ClC-5, in Dent's disease and knockout (KO) mice strongly inhibits endocytosis of filtered proteins by…”
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Rat muscle 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Study of the kinase domain by site-directed mutagenesis by CREPIN, K. M, VERTOMMEN, D, DOM, G, HUE, L, RIDER, M. H

“…Sequence alignment and modeling of the 2-kinase domain of the liver bifunctional enzyme, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase, on…”
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