Search Results - "Dolnikov, A"

Haematopoietic Stem Cell Transplants Enhance CART Cell Expansion and Persistence in Xenograft Mouse Model by Dolnikov, A

Get full text

Epigenetic agent modulates tumour microenvironment and potentiates cart cell therapy by Dolnikov, A, Xu, N, Tse, B, O'Brien, T

Get full text

Bromodomain inhibitor jq1 modulates immune suppressive pathways in neuroblastoma and enhances CARGD2T cell therapy by Dolnikov, A, Xu, N, Tse, B, Shen, S, O'Brien, T

Get full text

Using small molecule GSK3β inhibitors to treat inflammation by Klamer, G, Song, E, Ko, K-H, O'Brien, T A, Dolnikov, A

“…Glycogen Synthase Kinase 3 beta (GSK3β) is a serine-threonine kinase originally identified for its role in the conversion of glucose to glycogen…”
Get more information

Use of HDACi and PD-1/PD-L1 Blockade to Enhance Cytolytic Activity of Ex Vivo Expanded NK Cells Against Neuroblastoma by Shen, S, Dolnikov, A, O'Brien, T

Get full text

Tumour microenvironment modulates cart cell fate in paediatric leukemia by Tse, B, Xu, N, Bishop, D, Gottlieb, D, Micklethwaite, K, O'Brien, T, Dolnikov, A

Get full text

Factors promoting CD19-negative relapses following CAR19T cell therapy by Dolnikov, A, Xu, N, Tse, B, Bishop, D, Gottlieb, D, Micklethwaite, K, O'Brien, T

Get full text

Imaging the dynamics of receptor-modified T cell effector function against leukaemia and neuroblastoma targets by Chaudhry, K, Shen, S, Wang, L, Bishop, D, Micklethwaite, K, Dolnikov, A, Nordon, R

Get full text

Stem Cell Approach to Generate Chimeric Antigen Receptor Modified Immune Effector Cells to Treat Cancer by Shen, S, Xu, N, Yang, S, O'Brien, T, Dolnikov, A

Get full text

Differing co-stimulatory, linker and spacer domains produce variations in CD4 and CD8 cell composition and cytotoxic potential in CD19-specific chimeric antigen receptor (CAR19) T cells generated with the piggyBac transposase by Bishop, D, Xu, N, Shen, S, O'Brien, T, Gottlieb, D, Dolnikov, A, Micklethwaite, K

Get full text

Prolonging CART Cell Persistence Using Conditioning with 5-Azacytidine by Dolnikov, A, Yang, S, Shen, S, Xu, N, Chaudhry, K, Nordon, R, O'Brien, T

Get full text

Increasing stem cell dose promotes the longevity of the graft in mice transplanted with human cord blood stem cells by Dolnikov, A, Xu, N, Shen, S, O'Brien, T

Get full text

GSK-3β inhibition promotes early engraftment of ex vivo-expanded haematopoietic stem cells by Dolnikov, A., Xu, N., Shen, S., Song, E., Holmes, T., Klamer, G., O'Brien, T. A.

“…Objectives Umbilical cord blood (UCB) is a source of stem cells used for allogeneic transplantation, in addition to bone marrow and peripheral blood. Limited…”
Get full text

Testing CAR-T cell activity in human hemato-chimeric mouse model with the normal range of antigen expression not resctricted to the tumour only by Dolnikov, A, Chitranjan, A, Shen, S, Klamer, G, O'Brien, T

Get full text

Identifying the factors modulating the efficacy of car-t cell therapy by Dolnikov, A, Klamer, G, Shen, S, Chitranjan, A, Carol, H, Lock, R, O'Brien, T

Get full text

GSK-3β inhibition promotes T cell reconstitution and preserves naïve T cell phenotype in mice transplanted with human haematopoietic stem cells by Dolnikov, A, Shen, S, Klamer, G, Xu, N, O'Brien, T.A

Get full text

Novel approach to generate chimeric antigen receptor (CAR) T cells using genetically modified T cell precursors by Shen, S, Xu, N, Klamer, G, O'Brien, T.A, Dolnikov, A

Get full text

Transient inhibition of GSK-3β promotes early and late engraftment of ex vivo expanded haematopoietic progenitor cells in immuno-compromised mice by Dolnikov, A, Holmes, T, Xu, N, Shen, S, Klamer, G, O'Brien, T.A

Get full text

Mutant N-ras Induces Myeloproliferative Disorders and Apoptosis in Bone Marrow Repopulated Mice by MacKenzie, K.L., Dolnikov, A., Millington, M., Shounan, Y., Symonds, G.

“…Mutations that activate the N-ras oncogene are among the most frequently detected genetic alterations in human acute myeloid leukemias (AMLs), Philadelphia…”
Get full text

Ex vivo expansion of cord blood progenitors impairs their short-term and long-term repopulating activity associated with transcriptional dysregulation of signalling networks by Holmes, T., Yan, F., Ko, K.-H., Nordon, R., Song, E., O'Brien, T. A., Dolnikov, A.

“…Objectives Cord blood (CB) has been established to be an alternative source of haematopoietic stem/progenitor cells (HPC) for transplantation. The number of…”
Get full text