Search Results - "Doll, Walter"

A single-dose, open-label, randomized, scintigraphic study to investigate the gastrointestinal behavior of 2 triple-combination cold products (acetaminophen, phenylephrine, and dextromethorphan) in healthy male volunteers by Mallefet, Pascal, Armogida, Marianna, Doll, Walter J, Page, Richard C, Sandefer, Erik P

“…Common cold symptoms may be mitigated by products in caplet, nasal spray, and oral solution formulations, although variations exist in the bioavailability of…”
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Systemic and mucosal immune responses following oral adenoviral delivery of influenza vaccine to the human intestine by radio controlled capsule by Kim, Leesun, Martinez, C. Josefina, Hodgson, Katie A., Trager, George R., Brandl, Jennifer R., Sandefer, Erik P., Doll, Walter J., Liebowitz, Dave, Tucker, Sean N.

“…There are several benefits of oral immunization including the ability to elicit mucosal immune responses that may protect against pathogens that invade through…”
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The effects of ulimorelin, a ghrelin agonist, on liquid gastric emptying and colonic transit in humans by James, Joyce, Mair, Stuart, Doll, Walter, Sandefer, Erik, Wurtman, David, Maurer, Alan, Deane, Adam M, Harris, M. Scott

“…Background Ulimorelin, a small molecule ghrelin agonist and prokinetic agent, was effective in animal models of gastroparesis and delayed transit. However,…”
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Pharmacokinetics of lisdexamfetamine dimesylate after targeted gastrointestinal release or oral administration in healthy adults by Ermer, James C, Haffey, Mary B, Doll, Walter J, Martin, Patrick, Sandefer, Erik P, Dennis, Kerry, Corcoran, Mary, Trespidi, Laura, Page, Richard C

“…The purpose of this work was to assess the pharmacokinetics and safety of lisdexamfetamine dimesylate (LDX) delivered and released regionally in the…”
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PMMA nanocomposites and gradient materials prepared by means of polysilsesquioxane (POSS) self-assembly by WEICKMANN, Hans, DELTO, Ralf, THOMANN, Ralf, BRENN, Rudiger, DOLL, Walter, MULHAUPT, Rolf

“…PMMA nanocomposites were prepared by means of self-assembly of polyhedral oligomeric silsesquioxanes (POSS) such as [Si8O12(OSiMe2H)8] (POSS1) and…”
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Intranasal versus Oral Administration of Lisdexamfetamine Dimesylate: A Randomized, Open-Label, Two-Period, Crossover, Single-Dose, Single-Centre Pharmacokinetic Study in Healthy Adult Men by Ermer, James C., Dennis, Kerry, Haffey, Mary B., Doll, Walter J., Sandefer, Erik P., Buckwalter, Mary, Page, Richard C., Diehl, Brian, Martin, Patrick T.

“…Background and Objective : Data on pharmacokinetic parameters of the prodrug stimulant lisdexamfetamine dimesylate via alternate routes of administration are…”
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Gamma scintigraphy for testing bioequivalence: A case study on two cromolyn sodium nasal spray preparations by Al-Ghananeem, Abeer M., Sandefer, Erik P., Doll, Walter J., Page, Richard C., Chang, Yunik, Digenis, George A.

“…The present work was carried out to study the deposition patterns and clearance of technetium-99m ( 99mTc) DTPA labeled cromolyn sodium (CS) solutions when…”
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Regional gastrointestinal delivery of remogliflozin etabonate in humans by O'Connor-Semmes, Robin L., Sandefer, Erik P., Hussey, Elizabeth K., Tao, Wenli, Doll, Walter J., Page, Richard C., Dobbins, Robert

“…ABSTRACT Remogliflozin etabonate (RE) is the prodrug of remogliflozin (R), an inhibitor of renal glucose transport designed to reduce blood glucose…”
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Su1778 RESULTS OF HUMAN DEVICE FUNCTION STUDIES FOR THE NAVICAP™ TARGETED ORAL DELIVERY PLATFORM IN HEALTHY VOLUNTEERS AND PATIENTS WITH UC by Lee, Shaoying N., Razag, Ghesal, Kelly, Colleen, Doll, Walter J., Sandefer, Erik P., Page, Richard C., Conklin, John, Shabram, Paul, Singh, Sharat, Kelman, Ariella

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S1058 A Scintigraphic Study to Evaluate the Safety, Tolerability, and Functions of a Drug Delivery System (DDS) Device in Healthy Subjects in Fasted State by Lee, Shaoying N., Sandefer, Erik, Stork, Cheryl, Doll, Walter, Page, Richard C., Quintana, Nelson, Wahl, Chris, Singh, Sharat

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S1061 A Scintigraphic Study to Evaluate the Localization and Delivery Function of a Drug Delivery System (DDS) Device in Patients With Active Ulcerative Colitis (UC) in a Fasted State by Martin, Kathleen, Lee, Shaoying N., Sandefer, Erik, Doll, Walter, Stork, Cheryl, Page, Richard C., Thomas, Stephen, Razag, Ghesal, Quintana, Nelson, Wahl, Chris, Singh, Sharat

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Sa1565 - Ulimorelin, an IV Ghrelin Agonist, Has Potent Prokinetic Effects in the Human Stomach but not Colon: Why an Active Drug May have Failed in Clinical Trials by James, Joyce, Doll, Walter J., Deane, Adam M., Mair, Stuart J., Maurer, Alan H., Harris, Scott

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Compartmental absorption modeling and site of absorption studies to determine feasibility of an extended-release formulation of an HIV-1 attachment inhibitor phosphate ester prodrug by Brown, Jonathan, Chien, Caly, Timmins, Peter, Dennis, Andrew, Doll, Walter, Sandefer, Erik, Page, Richard, Nettles, Richard E, Zhu, Li, Grasela, Dennis

“…BMS-663068 is a phosphonooxymethyl ester prodrug under development for the treatment of HIV/AIDS. The prodrug is designed to overcome the solubility-limited…”
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An in vitro-in vivo investigation of oral bioadhesive controlled release furosemide formulations by Santus, Giancarlo, Lazzarini, Caterina, Bottoni, Giuseppe, Sandefer, Erik P., Page, Richard C., Doll, Walter J., Ryo, U.Yun, Digenis, George A.

“…The in vitro controlled release and bioadhesive properties of furosemide formulations were evaluated with standard dissolution tests and with a specially…”
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Gamma scintigraphy: an evolving technology in pharmaceutical formulation development-Part 1 by Digenis, George A, Sandefer, Erik P, Page, Richard C, Doll, Walter J

“…Gamma scintigraphy provides a noninvasive method to `see' the in vivo fate of a pharmaceutical dosage form. The power of the technique is realized fully by…”
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In vivo evaluation of the absorption and gastrointestinal transit of avitriptan in fed and fasted subjects using gamma scintigraphy by Marathe, P H, Sandefer, E P, Kollia, G E, Greene, D S, Barbhaiya, R H, Lipper, R A, Page, R C, Doll, W J, Ryo, U Y, Digenis, G A

“…The study was conducted to assess the bioavailability of avitriptan after a standard high fat meal, in relation to gastrointestinal transit. Six healthy male…”
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Gamma scintigraphy: an evolving technology in pharmaceutical formulation development—Part 2 by Digenis, George A, Sandefer, Erik P, Page, Richard C, Doll, Walter J

“…In the second part of a two-part article, the authors provide further examples of the application of gamma scintigraphy in the evaluation of the in vivo…”
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Intranasal versus Oral Administration of Lisdexamfetamine Dimesylate by Ermer, James C, Dennis, Kerry, Haffey, Mary B, Doll, Walter J, Sandefer, Erik P, Buckwalter, Mary, Page, Richard C, Diehl, Brian, Martin, Patrick T

“…Background and Objective: Data on pharmacokinetic parameters of the prodrug stimulant lisdexamfetamine dimesylate via alternate routes of administration are…”
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Pharmacokinetics and gamma scintigraphy evaluation of two enteric coated formulations of didanosine in healthy volunteers by Damle, Bharat, Ullah, Ismat, Doll, Walter, Wiley, Gary, Knupp, Catherine

“…Aims The aims of the study were to evaluate the bioavailability of didanosine from the encapsulated enteric coated beads (1 × 200 mg; enteric beads) and…”
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