Search Results - "Dolinger, David L."
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Target Product Profile for a Diagnostic Assay to Differentiate between Bacterial and Non-Bacterial Infections and Reduce Antimicrobial Overuse in Resource-Limited Settings: An Expert Consensus
Published in PloS one (25-08-2016)“…Acute fever is one of the most common presenting symptoms globally. In order to reduce the empiric use of antimicrobial drugs and improve outcomes, it is…”
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A Collaborative Approach for “ReSeq-ing” Mycobacterium tuberculosis Drug Resistance: Convergence for Drug and Diagnostic Developers
Published in EBioMedicine (01-10-2015)Get full text
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Next-Generation Sequencing-Based User-Friendly Platforms for Drug-Resistant Tuberculosis Diagnosis: A Promise for the Near Future
Published in International journal of mycobacteriology (01-12-2016)“…Abstract Since 2002, there has been a gradual worldwide 1.3% annual decrease in the incidence of tuberculosis (TB). This is an encouraging statistic; however,…”
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A sensitive and specific point-of-care detection assay for Zaire Ebola virus
Published in Emerging microbes & infections (2017)“…Emerging Microbes & Infections (2017) 6, e5; doi: 10.1038/emi.2016.134 ; published online 18 January 2017…”
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Collaborative Effort for a Centralized Worldwide Tuberculosis Relational Sequencing Data Platform
Published in Clinical infectious diseases (15-10-2015)“…Continued progress in addressing challenges associated with detection and management of tuberculosis requires new diagnostic tools. These tools must be able to…”
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FIND Tuberculosis Strain Bank: a Resource for Researchers and Developers Working on Tests To Detect Mycobacterium tuberculosis and Related Drug Resistance
Published in Journal of clinical microbiology (01-04-2017)“…The spread of multidrug-resistant (MDR) tuberculosis (TB) and extensively drug-resistant (XDR) TB hampers global efforts in the fight against tuberculosis. To…”
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Limited Evidence for the Need for Region-Specific, Genotypic Drug-Susceptibility Assays for Mycobacterium tuberculosis
Published in Clinical infectious diseases (17-04-2018)Get full text
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Review of automated DNA extraction systems for sequencing-based solutions for drug-resistant tuberculosis detection
Published in Diagnostic microbiology and infectious disease (01-10-2020)“…Robust clinical specimen nucleic acid extraction instrumentation and methods are critical to the performance of downstream molecular diagnostics for the…”
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Integration of Published Information Into a Resistance-Associated Mutation Database for Mycobacterium tuberculosis
Published in The Journal of infectious diseases (01-04-2015)“…Tuberculosis remains a major global public health challenge. Although incidence is decreasing, the proportion of drug-resistant cases is increasing. Technical…”
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Analytical and Clinical Evaluation of the Epistem Genedrive Assay for Detection of Mycobacterium tuberculosis
Published in Journal of clinical microbiology (01-04-2016)“…The Epistem Genedrive assay rapidly detects the Mycobacterium tuberculosis omplex from sputum and is currently available for clinical use. However, the…”
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Collaborative Effort for a Centralized Worldwide Tuberculosis Relational Sequencing Data Platform: Figure 1
Published in Clinical infectious diseases (15-10-2015)Get full text
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Molecular Diagnostics and Active Screening for Health Care-Associated Infections: Stepping-Up the Game
Published in Laboratory medicine (01-05-2011)“…Health care-associated infections (HAI) place a significant burden up the health care system. Studies have shown that routine screening of patients prior to or…”
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Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment
Published in The European respiratory journal (01-04-2022)“…Approximately 85 000 deaths globally in 2019 were due to drug-resistant tuberculosis (TB), which corresponds to 7% of global deaths attributable to bacterial…”
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Molecular Diagnostics and Active Screening for Health Care-Associated Infections: Stepping-Up the Game: Table 1
Published in Laboratory medicine (01-05-2011)Get full text
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Covalent Modification of the β -1,4-N-acetylmuramoylhydrolase of Streptococcus faecium with 5-mercaptouridine Monophosphate
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1988)“…Purified β -1,4-N-acetylmuramoylhydrolase (muramidase-1; EC 3.2.1.17) of Streptococcus faecium ATCC 9790 has been shown to be covalently substituted with ≈ 12…”
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