Search Results - "Dolfe, Lisa"

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers by Cohen, Samuel I A, Arosio, Paolo, Presto, Jenny, Kurudenkandy, Firoz Roshan, Biverstål, Henrik, Dolfe, Lisa, Dunning, Christopher, Yang, Xiaoting, Frohm, Birgitta, Vendruscolo, Michele, Johansson, Jan, Dobson, Christopher M, Fisahn, André, Knowles, Tuomas P J, Linse, Sara

“…Aβ peptide aggregation is associated with Alzheimer's disease, and Aβ fibrils can catalyze formation of toxic oligomers. Molecular chaperone Brichos binds to…”
Get full text

BRICHOS binds to a designed amyloid-forming β-protein and reduces proteasomal inhibition and aggresome formation by Dolfe, Lisa, Winblad, Bengt, Johansson, Jan, Presto, Jenny

“…The BRICHOS domain is associated with proliferative, degenerative and amyloid diseases, and it has been shown to inhibit fibril formation and toxicity of the…”
Get more information

Dissociation of a BRICHOS trimer into monomers leads to increased inhibitory effect on Aβ42 fibril formation by Biverstål, Henrik, Dolfe, Lisa, Hermansson, Erik, Leppert, Axel, Reifenrath, Mara, Winblad, Bengt, Presto, Jenny, Johansson, Jan

“…The BRICHOS domain is associated with human amyloid disease, and it efficiently prevents amyloid fibril formation of the amyloid β-peptide (Aβ) in vitro and in…”
Get full text

THE MOLECULAR CHAPERONE BRICHOS INHIBITS Aβ AGGREGATION AND OTHER NEUROPATHOLOGICAL PHENOTYPES IN A MOUSE MODEL OF Aβ AMYLOIDOSIS by Kim, Jungsu, Kim, Chaeyoung, Dolfe, Lisa, Belmonte, Krystal, Flores, Luis, Kurti, Aishe, Fryer, John D., Presto, Jenny, Johansson, Jan

Get full text

Brichos Interactions with Amyloid Proteins and Implications for Alzheimer Disease by Dolfe, Lisa

“…To date, about 30 diseases, in which amyloid fibrils form extracellular deposits, have been identified in humans. It is not known if the fibrils have a…”
Get full text

The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ 42 and Alzheimer Amyloid Plaques by Dolfe, Lisa, Tambaro, Simone, Tigro, Helene, Del Campo, Marta, Hoozemans, Jeroen J M, Wiehager, Birgitta, Graff, Caroline, Winblad, Bengt, Ankarcrona, Maria, Kaldmäe, Margit, Teunissen, Charlotte E, Rönnbäck, Annica, Johansson, Jan, Presto, Jenny

“…Alzheimer's disease (AD) is the most common form of dementia and there is no successful treatment available. Evidence suggests that fibril formation of the…”
Get full text

A molecular chaperone breaks the catalytic cycle that generates toxic A[beta] oligomers by Cohen, Samuel I A, Arosio, Paolo, Presto, Jenny, Kurudenkandy, Firoz Roshan, Biverstål, Henrik, Dolfe, Lisa, Dunning, Christopher, Yang, Xiaoting, Frohm, Birgitta, Vendruscolo, Michele, Johansson, Jan, Dobson, Christopher M, Fisahn, Andre, Knowles, Tuomas P.J, Linse, Sara

“…A[beta] peptide aggregation is associated with Alzheimer's disease, and A[beta] fibrils can catalyze formation of toxic oligomers. Molecular chaperone Brichos…”
Get full text

The molecular chaperone Brichos breaks the catalytic cycle that generates toxic Aβ oligomers by Cohen, Samuel I. A., Arosio, Paolo, Presto, Jenny, Kurudenkandy, Firoz Roshan, Biverstal, Henrik, Dolfe, Lisa, Dunning, Christopher, Yang, Xiaoting, Frohm, Birgitta, Vendruscolo, Michele, Johansson, Jan, Dobson, Christopher M., Fisahn, André, Knowles, Tuomas P. J., Linse, Sara

“…Alzheimer’s disease is an increasingly prevalent neurodegenerative disorder whose pathogenesis has been associated with aggregation of the amyloid-β peptide…”
Get full text

The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ42 and Alzheimer Amyloid Plaques by Dolfe, Lisa, Tambaro, Simone, Tigro, Helene, Del Campo, Marta, Hoozemans, Jeroen J.M., Wiehager, Birgitta, Graff, Caroline, Winblad, Bengt, Ankarcrona, Maria, Kaldmäe, Margit, Teunissen, Charlotte E., Rönnbäck, Annica, Johansson, Jan, Presto, Jenny

“…Alzheimer’s disease (AD) is the most common form of dementia and there is no successful treatment available. Evidence suggests that fibril formation of the…”
Get full text