Search Results - "DoleŽal, Tomáš"

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense by Krejčová, Gabriela, Danielová, Adéla, Nedbalová, Pavla, Kazek, Michalina, Strych, Lukáš, Chawla, Geetanjali, Tennessen, Jason M, Lieskovská, Jaroslava, Jindra, Marek, Doležal, Tomáš, Bajgar, Adam

“…Macrophage-mediated phagocytosis and cytokine production represent the front lines of resistance to bacterial invaders. A key feature of this pro-inflammatory…”
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Glucose and trehalose metabolism through the cyclic pentose phosphate pathway shapes pathogen resistance and host protection in Drosophila by Kazek, Michalina, Chodáková, Lenka, Lehr, Katharina, Strych, Lukáš, Nedbalová, Pavla, McMullen, Ellen, Bajgar, Adam, Opekar, Stanislav, Šimek, Petr, Moos, Martin, Doležal, Tomáš

“…Activation of immune cells requires the remodeling of cell metabolism in order to support immune function. We study these metabolic changes through the…”
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Measurement of electrical conductivity of human tissue: A feasibility study of a novel time-domain approach by Doležal, Tomáš, Štumpf, Martin, Hua, Qirui, Franek, Ondrej

“…A straightforward, non-invasive experimental approach to the extraction of electrical conductivity of human tissue using the transient electromagnetic field…”
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New insights into the burden and costs of multiple sclerosis in Europe: Results of the Czech Republic by Havrdova, Eva, Kobelt, Gisela, Berg, Jenny, Capsa, Daniela, Gannedahl, Mia, Doležal, Tomáš

“…Introduction: In order to estimate the value of interventions in multiple sclerosis (MS) – where lifetime costs and outcomes cannot be observed – outcome data…”
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Polarization of Macrophages in Insects: Opening Gates for Immuno-Metabolic Research by Bajgar, Adam, Krejčová, Gabriela, Doležal, Tomáš

“…Insulin resistance and cachexia represent severe metabolic syndromes accompanying a variety of human pathological states, from life-threatening cancer and…”
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Time in remission as an alternative outcome measure for rheumatoid arthritis: a 10-year prospective study of 2618 new users of anti-TNF by Tužil, Jan, Mlčoch, Tomáš, Závada, Jakub, Svoboda, Michal, Pavelka, Karel, Doležal, Tomáš

“…Abstract Objective Achieving targeted disease activity (DA) is the primary therapeutic strategy in RA. Point measurements of DA are done at out-patient visits,…”
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Runoff formation in a catchment with Peat bog and Podzol hillslopes by Vlček, Lukáš, Šípek, Václav, Kofroňová, Jitka, Kocum, Jan, Doležal, Tomáš, Janský, Bohumír

“…[Display omitted] •Runoff formation at two different soils forming two hillslopes at one catchment was studied.•HBV model was used for estimation of a peat bog…”
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Macrophage‐derived insulin antagonist ImpL2 induces lipoprotein mobilization upon bacterial infection by Krejčová, Gabriela, Morgantini, Cecilia, Zemanová, Helena, Lauschke, Volker M, Kovářová, Julie, Kubásek, Jiří, Nedbalová, Pavla, Kamps‐Hughes, Nick, Moos, Martin, Aouadi, Myriam, Doležal, Tomáš, Bajgar, Adam

“…The immune response is an energy‐demanding process that must be coordinated with systemic metabolic changes redirecting nutrients from stores to the immune…”
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Short-term risk of periprocedural stroke relative to radial vs. femoral access: systematic review, meta-analysis, study sequential analysis and meta-regression of 2,188,047 real-world cardiac catheterizations by Tužil, Jan, Matějka, Jan, Mamas, Mamas A, Doležal, Tomáš

“…To verify whether transradial (TRA) compared to transfemoral (TFA) cardiac catheterization reduces the risk of periprocedural stroke (PS). We reviewed…”
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Relationship between Patient Preferences, Attitudes to Treatment, Adherence, and Quality of Life in New Users of Teriflunomide by Štrosová, Daniela, Tužil, Jan, Turková, Barbora Velacková, Pilnáčková, Barbora Filková, de Souza, Lada Lžičařová, Doležalová, Helena, Rašková, Michaela, Dufek, Michal, Doležal, Tomáš

“…Background: A poor patient adherence often limits the real-world effectiveness of an oral disease-modifying therapy (DMT) for multiple sclerosis (MS). In the…”
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Ultrahypofractionated Proton Radiation Therapy in the Treatment of Low and Intermediate-Risk Prostate Cancer-5-Year Outcomes by Kubeš, Jiří, Haas, Alexandra, Vondráček, Vladimír, Andrlík, Michal, Navrátil, Matěj, Sláviková, Silvia, Vítek, Pavel, Dědečková, Kateřina, Prausová, Jana, Ondrová, Barbora, Vinakurau, Štěpán, Grebenyuk, Alexander, Doležal, Tomáš, Velacková, Barbora, Rosina, Jozef

“…To analyze the 5-year biochemical disease-free survival (bDFS) and late toxicity profile in patients with prostate cancer treated with pencil beam scanning…”
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Transferability of new methods for health technology assessment in the field of diabetes between early and late adopters’ countries by Tachkov, Konstantin, Somolinos-Simón, Francisco, Tapia-Galisteo, Jose, Hernando, Maria Elena, García-Sáez, Gema, Dimitrova, Maria, Kamusheva, Maria, Mitkova, Zornitsa, Petyko, Zsuzsanna, Nemeth, Bertalan, Kalo, Zoltan, Tesar, Tomas, Paveliu, Marian-Sorin, Piniazhko, Oresta, Lipska, Iga, Turcu-Stiolica, Adina, Savova, Alexandra, Manova, Manoela, Hren, Rok, Došenović Bonča, Petra, Knies, Saskia, Stanak, Michal, Doležal, Tomáš, Vitezic, Dinko, Petrova, Guenka

“…This study aimed to investigate the transferability of novel artificial intelligence (AI) methods for prediction modelling of diabetes based on real-world data…”
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Yeast glucan particles enable intracellular protein delivery in Drosophila without compromising the immune system by Bajgar, Adam, Saloň, Ivan, Krejčová, Gabriela, DoleŽal, Tomáš, Jindra, Marek, Štěpánek, František

“…Glucan particles derived from yeast have been recently proposed as potential drug delivery carriers. Here, we demonstrate the potential of glucan particles for…”
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Real-life experience in the effectiveness, impact on quality of life and safety of dupilumab treatment in patients with moderate to severe atopic dermatitis in the Czech Republic by Tánczosová, Milena, Kojanová, Martina, Arenbergerová, Monika, Arenberger, Petr, Doležal, Tomáš, Štrosová, Daniela, Fialová, Jorga, Gkalpakiotis, Spyridon

“…The aim of the study was to assess the effectiveness and safety of dupilumab therapy in patients with moderate-to-severe atopic dermatitis (AD) in a real-life…”
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Accession Site Does Not Influence the Risk of Stroke after Diagnostic Coronary Angiography or Intervention: Results from a Large Prospective Registry by Matějka, Jan, Varvařovský, Ivo, Tužil, Jan, Doležal, Tomáš, Bobak, Martin, Pospíchal, Jan, Geier, Petr, Vondrák, Jiří, Bláha, Karel, Málek, Jan, Staňková, Alena, Bujdák, Juraj, Rozsíval, Vladimír, Novotný, Vojtěch, Lazarák, Tomáš, Plíva, Milan, Večeřa, Jan, Vojtíšek, Petr

“…Introduction: Periprocedural stroke represents a rare but serious complication of cardiac catheterization. Pooled data from randomized trials evaluating the…”
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5-Years Analysis of Effectivity and Toxicity of Ultra-Hypofractionated Proton Radiotherapy in the Treatment of Low- and Intermediate-Risk Prostate Cancer—A Retrospective Analysis by Kubeš, Jiri, Sláviková, Silvia, Vítek, Pavel, Haas, Alexandra, Ondrová, Barbora, Dedečková, Kateřina, Andrlík, Michal, Domanský, Martin, Jiránková, Kateřina, Schlencová, Veronika, Harazimová, Anh, Turková, Barbora, Doležal, Tomáš, Al-Hamami, Sarah Falah Abass, Vondráček, Vladimír

“…Background: We retrospectively analyzed the 5-year biochemical disease-free survival (bDFS) and occurrence of late toxicity in prostate cancer patients treated…”
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Health and economic impact of subcutaneous allergen immunotherapy in patients with pollen-induced allergic rhinoconjunctivitis: real-word evidence from the Czech Republic by Turkoá, Barbora, Tužil, Jan, Pilnáčková, Barbora, Doležalová, Helena, Štrosová, Daniela, Petrů, Vít, Seberová, Ester, Doležal, Tomáš

“…The prevalence of allergic rhinoconjunctivitis (AR) has been increasing over the years, and allergen immunotherapy (AIT) remains the only disease-modifying…”
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Breast cancer-specific mutations in CK1ε inhibit Wnt/β-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration by Foldynová-Trantírková, Silvie, Sekyrová, Petra, Tmejová, Kateřina, Brumovská, Eva, Bernatík, Ondřej, Blankenfeldt, Wulf, Krejčí, Pavel, Kozubík, Alois, Doležal, Tomáš, Trantírek, Lukáš, Bryja, Vítězslav

“…Abstract Introduction Breast cancer is one of the most common types of cancer in women. One of the genes that were found mutated in breast cancer is casein…”
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Cost-of-illness analysis and regression modeling in cystic fibrosis: a retrospective prevalence-based study by Mlčoch, Tomáš, Klimes, Jiří, Fila, Libor, Vávrová, Věra, Skalická, Veronika, Turnovec, Marek, Krulišová, Veronika, Jirčíková, Jitka, Zemková, Dana, Děděcková, Klára Vilimovská, Bílková, Alena, Frühaufová, Vladimíra, Homola, Lukáš, Friedmannová, Zuzana, Drnek, Radovan, Dřevínek, Pavel, Doležal, Tomáš, Macek, Milan

“…Background Economic data pertaining to cystic fibrosis (CF), is limited in Europe generally, and completely lacking in Central and Eastern Europe. We performed…”
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Cost of severe hypoglycaemia in nine European countries by Jakubczyk, Michał, Lipka, Izabela, Pawęska, Justyna, Niewada, Maciej, Rdzanek, Elżbieta, Zaletel, Jelka, Ramírez de Arellano, Antonio, Doležal, Tomáš, Chekorova Mitreva, Biljana, Nagy, Bence, Petrova, Guenka, Šarić, Tereza, Yfantopoulos, John, Czech, Marcin

“…Complications contribute largely to the economic gravity of diabetes mellitus (DM). How they arise and are treated differs substantially between countries…”
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