Search Results - "Dold, Christina"

MAIT cell activation augments adenovirus vector vaccine immunogenicity by Provine, Nicholas M, Amini, Ali, Garner, Lucy C, Spencer, Alexandra J, Dold, Christina, Hutchings, Claire, Silva Reyes, Laura, FitzPatrick, Michael E B, Chinnakannan, Senthil, Oguti, Blanche, Raymond, Meriel, Ulaszewska, Marta, Troise, Fulvia, Sharpe, Hannah, Morgan, Sophie B, Hinks, Timothy S C, Lambe, Teresa, Capone, Stefania, Folgori, Antonella, Barnes, Eleanor, Rollier, Christine S, Pollard, Andrew J, Klenerman, Paul

“…Mucosal-associated invariant T (MAIT) cells are innate sensors of viruses and can augment early immune responses and contribute to protection. We hypothesized…”
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Immune responses to Neisseria gonorrhoeae and implications for vaccine development by Belcher, Thomas, Rollier, Christine S, Dold, Christina, Ross, Jonathan D C, MacLennan, Calman A

“…is the causative agent of gonorrhea, a sexually transmitted infection responsible for a major burden of disease with a high global prevalence. Protective…”
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Distinct patterns of whole blood transcriptional responses are induced in mice following immunisation with adenoviral and poxviral vector vaccines encoding the same antigen by Sheerin, Dylan, Dold, Christina, O'Connor, Daniel, Pollard, Andrew J, Rollier, Christine S

“…Viral vectors, including adenovirus (Ad) and modified vaccinia Ankara (MVA), have gained increasing attention as vaccine platforms in recent years due to their…”
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Gene expression profiling reveals insights into infant immunological and febrile responses to group B meningococcal vaccine by O’Connor, Daniel, Pinto, Marta Valente, Sheerin, Dylan, Tomic, Adriana, Drury, Ruth E, Channon‐Wells, Samuel, Galal, Ushma, Dold, Christina, Robinson, Hannah, Kerridge, Simon, Plested, Emma, Hughes, Harri, Stockdale, Lisa, Sadarangani, Manish, Snape, Matthew D, Rollier, Christine S, Levin, Michael, Pollard, Andrew J

“…Neisseria meningitidis is a major cause of meningitis and septicaemia. A MenB vaccine (4CMenB) was licensed by the European Medicines Agency in January 2013…”
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Inclusion of a dual signal sequence enhances the immunogenicity of a novel viral vectored vaccine against the capsular group B meningococcus by Sheerin, Dylan, Dold, Christina, Silva-Reyes, Laura, Linder, Aline, Pollard, Andrew J, Rollier, Christine S

“…Disease caused by the capsular group B meningococcus (MenB) is the leading cause of infectious death in UK infants. A novel adenovirus-based vaccine encoding…”
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Cellular immunity to SARS-CoV-2 following intrafamilial exposure in seronegative family members by Jay, Cecilia, Adland, Emily, Csala, Anna, Dold, Christina, Edmans, Matthew, Hackstein, Carl-Philipp, Jamsen, Anni, Lim, Nicholas, Longet, Stephanie, Ogbe, Ane, Sampson, Oliver, Skelly, Donal, Spiller, Owen B, Stafford, Lizzie, Thompson, Craig P, Turtle, Lance, Barnes, Ellie, Dunachie, Susanna, Carroll, Miles, Klenerman, Paul, Conlon, Chris, Goulder, Philip, Jones, Lucy C

“…Family studies of antiviral immunity provide an opportunity to assess virus-specific immunity in infected and highly exposed individuals, as well as to examine…”
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Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of Coxiella burnetii Immunity by Sluder, Ann E, Raju Paul, Susan, Moise, Leonard, Dold, Christina, Richard, Guilhem, Silva-Reyes, Laura, Baeten, Laurie A, Scholzen, Anja, Reeves, Patrick M, Pollard, Andrew J, Garritsen, Anja, Bowen, Richard A, De Groot, Anne S, Rollier, Christine, Poznansky, Mark C

“…T cell-mediated immunity plays a central role in the control and clearance of intracellular infection, which can cause Q fever. Therefore, we aimed to develop…”
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An exploratory analysis of the response to ChAdOx1 nCoV-19 (AZD1222) vaccine in males and females by Marchevsky, Natalie Gabrielle, Li, Grace, Aley, Parvinder, Costa Clemens, Sue Ann, Barrett, Jordan Richard, Belij-Rammerstorfer, Sandra, Bibi, Sagida, Clutterbuck, Elizabeth, Dold, Christina, Felle, Sally, Flaxman, Amy, Folegatti, Pedro, Jenkin, Daniel, Gilbert, Sarah, Kelly, Sarah, Lambe, Teresa, Plested, Emma, Ramasamy, Maheshi, Singh, Nisha, Smith, Holly, Taylor, Stephen, Weckx, Lily, Pollard, Andrew John, Voysey, Merryn

“…There are known differences in vaccine reactogenicity and immunogenicity by sex. Females have been shown to report greater reactogenicity and generate higher…”
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A Salmonella Typhi Controlled Human Infection Study for Assessing Correlation between Bactericidal Antibodies and Protection against Infection Induced by Typhoid Vaccination by Jones, Elizabeth, Jin, Celina, Stockdale, Lisa, Dold, Christina, Pollard, Andrew J., Hill, Jennifer

“…Vi-polysaccharide conjugate vaccines are efficacious against typhoid fever in children living in endemic settings, their recent deployment is a promising step…”
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FetA Antibodies Induced by an Outer Membrane Vesicle Vaccine Derived from a Serogroup B Meningococcal Isolate with Constitutive FetA Expression by Sanders, Holly, Norheim, Gunnstein, Chan, Hannah, Dold, Christina, Vipond, Caroline, Derrick, Jeremy P, Pollard, Andrew J, Maiden, Martin C J, Feavers, Ian M

“…Invasive meningococcal disease causes over 3500 cases each year in Europe, with particularly high incidence among young children. Among serogroup B…”
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Impact of Reducing Complement Inhibitor Binding on the Immunogenicity of Native Neisseria meningitidis Outer Membrane Vesicles by Daniels-Treffandier, Helene, de Nie, Karlijn, Marsay, Leanne, Dold, Christina, Sadarangani, Manish, Reyes-Sandoval, Arturo, Langford, Paul R, Wyllie, David, Hill, Fergal, Pollard, Andrew J, Rollier, Christine S

“…Neisseria meningitidis recruits host human complement inhibitors to its surface to down-regulate complement activation and enhance survival in blood. We have…”
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Human B Cell Responses to Dominant and Subdominant Antigens Induced by a Meningococcal Outer Membrane Vesicle Vaccine in a Phase I Trial by Rollier, Christine S, Dold, Christina, Marsay, Leanne, Linder, Aline, Green, Christopher A, Sadarangani, Manish, Norheim, Gunnstein, Derrick, Jeremy P, Feavers, Ian M, Maiden, Martin C J, Pollard, Andrew J

“…Neisseria meningitidis outer membrane vesicle (OMV) vaccines are safe and provide strain-specific protection against invasive meningococcal disease (IMD)…”
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Anti-Factor H Antibody Reactivity in Young Adults Vaccinated with a Meningococcal Serogroup B Vaccine Containing Factor H Binding Protein by Sharkey, Kelsey, Beernink, Peter T, Langley, Joanne M, Gantt, Soren, Quach, Caroline, Dold, Christina, Liu, Qin, Galvan, Manuel, Granoff, Dan M

“…Meningococcal serogroup B (MenB) vaccines contain recombinant factor H binding protein (FHbp), which can complex with complement factor H (CFH) and thereby…”
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Ascaris and ascariasis by Dold, Christina, Holland, Celia V.

“…Ascaris lumbricoides and Ascaris suum are widespread parasitic nematodes of humans and pigs respectively. Recent prevalence data suggests that approximately…”
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Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera by Zhou, Daming, Dejnirattisai, Wanwisa, Supasa, Piyada, Liu, Chang, Mentzer, Alexander J., Ginn, Helen M., Zhao, Yuguang, Duyvesteyn, Helen M.E., Tuekprakhon, Aekkachai, Nutalai, Rungtiwa, Wang, Beibei, Paesen, Guido C., Lopez-Camacho, Cesar, Slon-Campos, Jose, Hallis, Bassam, Coombes, Naomi, Bewley, Kevin, Charlton, Sue, Walter, Thomas S., Skelly, Donal, Lumley, Sheila F., Dold, Christina, Levin, Robert, Dong, Tao, Pollard, Andrew J., Knight, Julian C., Crook, Derrick, Lambe, Teresa, Clutterbuck, Elizabeth, Bibi, Sagida, Flaxman, Amy, Bittaye, Mustapha, Belij-Rammerstorfer, Sandra, Gilbert, Sarah, James, William, Carroll, Miles W., Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.

“…The race to produce vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began when the first sequence was published, and this forms…”
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Antibody evasion by the P.1 strain of SARS-CoV-2 by Dejnirattisai, Wanwisa, Zhou, Daming, Supasa, Piyada, Liu, Chang, Mentzer, Alexander J., Ginn, Helen M., Zhao, Yuguang, Duyvesteyn, Helen M.E., Tuekprakhon, Aekkachai, Nutalai, Rungtiwa, Wang, Beibei, López-Camacho, César, Slon-Campos, Jose, Walter, Thomas S., Skelly, Donal, Costa Clemens, Sue Ann, Naveca, Felipe Gomes, Nascimento, Valdinete, Nascimento, Fernanda, Fernandes da Costa, Cristiano, Resende, Paola Cristina, Pauvolid-Correa, Alex, Siqueira, Marilda M., Dold, Christina, Levin, Robert, Dong, Tao, Pollard, Andrew J., Knight, Julian C., Crook, Derrick, Lambe, Teresa, Clutterbuck, Elizabeth, Bibi, Sagida, Flaxman, Amy, Bittaye, Mustapha, Belij-Rammerstorfer, Sandra, Gilbert, Sarah C., Carroll, Miles W., Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Paterson, Neil G., Williams, Mark A., Hall, David R., Hulswit, Ruben J.G., Bowden, Thomas A., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.

“…Terminating the SARS-CoV-2 pandemic relies upon pan-global vaccination. Current vaccines elicit neutralizing antibody responses to the virus spike derived from…”
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Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial by Emary, Katherine R W, Golubchik, Tanya, Aley, Parvinder K, Ariani, Cristina V, Angus, Brian, Bibi, Sagida, Blane, Beth, Bonsall, David, Cicconi, Paola, Charlton, Sue, Clutterbuck, Elizabeth A, Collins, Andrea M, Cox, Tony, Darton, Thomas C, Dold, Christina, Douglas, Alexander D, Duncan, Christopher J A, Ewer, Katie J, Flaxman, Amy L, Faust, Saul N, Ferreira, Daniela M, Feng, Shuo, Finn, Adam, Folegatti, Pedro M, Fuskova, Michelle, Galiza, Eva, Goodman, Anna L, Green, Catherine M, Green, Christopher A, Greenland, Melanie, Hallis, Bassam, Heath, Paul T, Hay, Jodie, Hill, Helen C, Jenkin, Daniel, Kerridge, Simon, Lazarus, Rajeka, Libri, Vincenzo, Lillie, Patrick J, Ludden, Catherine, Marchevsky, Natalie G, Minassian, Angela M, McGregor, Alastair C, Mujadidi, Yama F, Phillips, Daniel J, Plested, Emma, Pollock, Katrina M, Robinson, Hannah, Smith, Andrew, Song, Rinn, Snape, Matthew D, Sutherland, Rebecca K, Thomson, Emma C, Toshner, Mark, Turner, David P J, Vekemans, Johan, Villafana, Tonya L, Williams, Christopher J, Hill, Adrian V S, Lambe, Teresa, Gilbert, Sarah C, Voysey, Merryn, Ramasamy, Maheshi N, Pollard, Andrew J

“…A new variant of SARS-CoV-2, B.1.1.7, emerged as the dominant cause of COVID-19 disease in the UK from November, 2020. We report a post-hoc analysis of the…”
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Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity by Boulenouar, Selma, Michelet, Xavier, Duquette, Danielle, Alvarez, David, Hogan, Andrew E., Dold, Christina, O’Connor, Donal, Stutte, Suzanne, Tavakkoli, Ali, Winters, Desmond, Exley, Mark A., O’Shea, Donal, Brenner, Michael B., von Andrian, Ulrich, Lynch, Lydia

“…Adipose tissue has a dynamic immune system that adapts to changes in diet and maintains homeostatic tissue remodeling. Adipose type 1 innate lymphoid cells…”
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SIMON, a powerful AI software accelerating discovery of human immune memory responses to viruses by Tomic, Adriana, Tomic, Ivan, Skelly, Donal T, Ogbe, Ane, O’Connor, Daniel, Pollard, Andrew J, Dold, Christina, Barnes, Eleanor, Klenerman, Paul, Dunachie, Susanna, Davis, Mark M, consortium, PITCH

“…Abstract Influenza and SARS-CoV-2 are among the greatest viral threats to human health causing the 20th and 21st centuries’ most significant pandemics. These…”
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Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in HIV infection: a single-arm substudy of a phase 2/3 clinical trial by Frater, John, Ewer, Katie J, Ogbe, Ane, Pace, Mathew, Adele, Sandra, Adland, Emily, Alagaratnam, Jasmini, Aley, Parvinder K, Ali, Mohammad, Ansari, M Azim, Bara, Anna, Bittaye, Mustapha, Broadhead, Samantha, Brown, Anthony, Brown, Helen, Cappuccini, Federica, Cooney, Enya, Dejnirattisai, Wanwisa, Dold, Christina, Fairhead, Cassandra, Fok, Henry, Folegatti, Pedro M, Fowler, Jamie, Gibbs, Charlotte, Goodman, Anna L, Jenkin, Daniel, Jones, Mathew, Makinson, Rebecca, Marchevsky, Natalie G, Mujadidi, Yama F, Nguyen, Hanna, Parolini, Lucia, Petersen, Claire, Plested, Emma, Pollock, Katrina M, Ramasamy, Maheshi N, Rhead, Sarah, Robinson, Hannah, Robinson, Nicola, Rongkard, Patpong, Ryan, Fiona, Serrano, Sonia, Tipoe, Timothy, Voysey, Merryn, Waters, Anele, Zacharopoulou, Panagiota, Barnes, Eleanor, Dunachie, Susanna, Goulder, Philip, Klenerman, Paul, Screaton, Gavin R, Winston, Alan, Hill, Adrian V S, Gilbert, Sarah C, Pollard, Andrew J, Fidler, Sarah, Fox, Julie, Lambe, Teresa, Watson, Marion E.E., Song, Rinn, Cicconi, Paola, Minassian, Angela M., Bibi, Sagida, Kerridge, Simon, Singh, Nisha, Green, Catherine M., Douglas, Alexander D., Lawrie, Alison M., Clutterbuck, Elizabeth A.

“…Data on vaccine immunogenicity against SARS-CoV-2 are needed for the 40 million people globally living with HIV who might have less functional immunity and…”
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