Search Results - "Dolci, Wanda"

α-cell glucokinase suppresses glucose-regulated glucagon secretion by Basco, Davide, Zhang, Quan, Salehi, Albert, Tarasov, Andrei, Dolci, Wanda, Herrera, Pedro, Spiliotis, Ioannis, Berney, Xavier, Tarussio, David, Rorsman, Patrik, Thorens, Bernard

“…Glucagon secretion by pancreatic α-cells is triggered by hypoglycemia and suppressed by high glucose levels; impaired suppression of glucagon secretion is a…”
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Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in β-cells by Deisl, Christine, Simonin, Alexandre, Anderegg, Manuel, Albano, Giuseppe, Kovacs, Gergely, Ackermann, Daniel, Moch, Holger, Dolci, Wanda, Thorens, Bernard, Hediger, Matthias A., Fuster, Daniel G.

“…NHA2 is a sodium/hydrogen exchanger with unknown physiological function. Here we show that NHA2 is present in rodent and human β-cells, as well as β-cell…”
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Increasing GLP-1–Induced β-Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator-α and DUSP14 by Klinger, Sonia, Poussin, Carine, Debril, Marie-Bernard, Dolci, Wanda, Halban, Philippe A, Thorens, Bernard

“…Increasing GLP-1–Induced β-Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator-α and DUSP14 Sonia Klinger 1 ,…”
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Long-lasting antidiabetic effect of a dipeptidyl peptidase IV-resistant analog of glucagon-like peptide-1 by Burcelin, Rémy, Dolci, Wanda, Thorens, Bernard

“…Glucagon-like peptide-1(7–37) (GLP-1) is the most potent insulinotropic hormone characterized thus far. Because its activity is preserved in…”
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cFLIP Protein Prevents Tumor Necrosis Factor-α–Mediated Induction of Caspase-8–Dependent Apoptosis in Insulin-Secreting βTc-Tet Cells by COTTET, Sandra, DUPRAZ, Philippe, HAMBURGER, Fabienne, DOLCI, Wanda, JAQUET, Muriel, THORENS, Bernard

“…cFLIP Protein Prevents Tumor Necrosis Factor-α–Mediated Induction of Caspase-8–Dependent Apoptosis in Insulin-Secreting βTc-Tet Cells Sandra Cottet , Philippe…”
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Fgf15 neurons of the dorsomedial hypothalamus control glucagon secretion and hepatic gluconeogenesis by Picard, Alexandre, Metref, Salima, Tarussio, David, Dolci, Wanda, Berney, Xavier, Croizier, Sophie, Labouebe, Gwenaël, Thorens, Bernard

“…The counterregulatory response to hypoglycemia is an essential survival function. It is controlled by an integrated network of glucose responsive neurons,…”
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Heterologous Desensitization of the Glucagon-like Peptide-1 Receptor by Phorbol Esters Requires Phosphorylation of the Cytoplasmic Tail at Four Different Sites by Widmann, Christian, Dolci, Wanda, Thorens, Bernard

“…Glucagon-like peptide-1 stimulates glucose-induced insulin secretion by binding to a specific G protein-coupled receptor that activates the adenylyl cyclase…”
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Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice by BURCELIN, Rémy, DOLCI, Wanda, THORENS, Bernard

“…Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice. R Burcelin , W Dolci and B Thorens Institute of…”
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Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in [Beta]-cells by Deisl, Christine, Simonin, Alexandre, Anderegg, Manuel, Albano, Giuseppe, Kovacs, Gergely, Ackermann, Daniel, Moch, Holger, Dolci, Wanda, Thorens, Bernard, Hediger, Matthias A, Fuster, Daniel G

“…NHA2 is a sodium/hydrogen exchanger with unknown physiological function. Here we show that NHA2 is present in rodent and human β-cells, as well as β-cell…”
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Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization by BURCELIN, Rémy, DOLCI, Wanda, THORENS, Bernard

“…Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization. R Burcelin , W Dolci…”
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Differential Sensitivity of GLUT1- and GLUT2-Expressing β Cells to Streptozotocin by Hosokawa, Masaya, Dolci, Wanda, Thorens, Bernard

“…Streptozotocin injection in animals destroys pancreatic β cells, leading to insulinopenic diabetes. Here, we evaluated the toxic effect of streptozotocin (STZ)…”
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Regulated exocytosis of an H+/myo-inositol symporter at synapses and growth cones by Uldry, Marc, Steiner, Pascal, Zurich, Marie-Gabrielle, Béguin, Pascal, Hirling, Harald, Dolci, Wanda, Thorens, Bernard

“…Phosphoinositides, synthesized from myo‐inositol, play a critical role in the development of growth cones and in synaptic activity. As neurons cannot…”
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Internalization and Homologous Desensitization of the GLP-1 Receptor Depend on Phosphorylation of the Receptor Carboxyl Tail at the Same Three Sites by Widmann, Christian, Dolci, Wanda, Thorens, Bernard

“…Homologous desensitization and internalization of the GLP-1 receptor correlate with phosphorylation of the receptor in a 33-amino acid segment of the…”
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Increasing GLP-1-Induced [beta]-Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator-[alpha] and DUSP14 by Klinger, Sonia, Poussin, Carine, Debril, Marie-Bernard, Dolci, Wanda, Halban, Philippe A, Thorens, Bernard

“…Glucagon-like peptide-1 (GLP-1) is a growth and differentiation factor for mature beta-cells and their precursors. However, the overall effect of GLP-1 on…”
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Dominant Negative MyD88 Proteins Inhibit Interleukin-1β/Interferon-γ-mediated Induction of Nuclear Factor κB-dependent Nitrite Production and Apoptosis in β Cells by Dupraz, Philippe, Cottet, Sandra, Hamburger, Fabienne, Dolci, Wanda, Felley-Bosco, Emanuella, Thorens, Bernard

“…Insulin-dependent diabetes mellitus is an autoimmune disease in which pancreatic islet β cells are destroyed by a combination of immunological and inflammatory…”
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Increasing GLP-1-Induced β-Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator-α and DUSP14. Commentary by SCHUIT, Frans C, DRUCKER, Daniel J, KLINGER, Sonia, POUSSIN, Carine, DEBRIL, Marie-Bernard, DOLCI, Wanda, HALBAN, Philippe A, THORENS, Bernard

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Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and beta-cell glucose competence by Serre, V, Dolci, W, Schaerer, E, Scrocchi, L, Drucker, D, Efrat, S, Thorens, B

“…The effect of exendin-(9-39), a described antagonist of the glucagon-like peptide-1 (GLP-1) receptor, was evaluated on the formation of cAMP- and…”
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SOCS-1 Protein Prevents Janus Kinase/STAT-dependent Inhibition of β Cell Insulin Gene Transcription and Secretion in Response to Interferon-γ by Cottet, Sandra, Dupraz, Philippe, Hamburger, Fabienne, Dolci, Wanda, Jaquet, Muriel, Thorens, Bernard

“…In the pathogenesis of type I diabetes mellitus, activated leukocytes infiltrate pancreatic islets and induce β cell dysfunction and destruction. Interferon…”
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Portal Glucose Infusion in the Mouse Induces Hypoglycemia by Burcelin, Remy, Dolci, Wanda, Thorens, Bernard

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Glucose Sensing by the Hepatoportal Sensor Is GLUT2-Dependent by Burcelin, Remy, Dolci, Wanda, Thorens, Bernard

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