Search Results - "Dolbier, William R"

Efficient Cu-catalyzed Atom Transfer Radical Addition Reactions of Fluoroalkylsulfonyl Chlorides with Electron-deficient Alkenes Induced by Visible Light by Tang, Xiao-Jun, Dolbier Jr, William R.

“…Fluoroalkylsulfonyl chlorides, RfSO2Cl, in which Rf=CF3, C4F9, CF2H, CH2F, and CH2CF3, are used as a source of fluorinated radicals to add fluoroalkyl groups…”
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Direct Photoredox-Catalyzed Reductive Difluoromethylation of Electron-Deficient Alkenes by Tang, Xiao-Jun, Zhang, Zuxiao, Dolbier Jr, William R.

“…Photoredox‐catalyzed reductive difluoromethylation of electron‐deficient alkenes was achieved in one step under tin‐free, mild and neutral conditions. This…”
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Photoredox-Catalyzed Tandem Radical Cyclization of N‑Arylacrylamides: General Methods To Construct Fluorinated 3,3-Disubstituted 2‑Oxindoles Using Fluoroalkylsulfonyl Chlorides by Tang, Xiao-Jun, Thomoson, Charles S, Dolbier, William R

“…Fluorinated radicals were generated from RfSO2Cl by photoredox catalysis under mild conditions, where Rf = n-C4F9, CF3, CF2H, CH2F, CH2CF3, and CF2CO2Me. This…”
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Photoredox-Catalyzed Intramolecular Aminodifluoromethylation of Unactivated Alkenes by Zhang, Zuxiao, Tang, Xiaojun, Thomoson, Charles S, Dolbier, Jr, William R

“…A photoredox catalyzed aminodifluoromethylation of unactivated alkenes has been developed in which HCF2SO2Cl is used as the HCF2 radical source. Sulfonamides…”
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Synthesis and Characterization of 2-Pyridylsulfur Pentafluorides by Kanishchev, Oleksandr S., Dolbier Jr, William R.

“…Current approaches to prepare SF5‐substituted heterocycles during the synthesis of targeted heterocyclic compounds require the use of SF5‐functionalized aryl…”
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Use of Fluoroform as a Source of Difluorocarbene in the Synthesis of Difluoromethoxy- and Difluorothiomethoxyarenes by Thomoson, Charles S, Dolbier, William R

“…Fluoroform, CHF3, a non-ozone-depleting, nontoxic, and inexpensive gas can be used as a difluoro­carbene source in a process for the conversion of phenols and…”
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Photoredox-Catalyzed Tandem Insertion/Cyclization Reactions of Difluoromethyl and 1,1-Difluoroalkyl Radicals with Biphenyl Isocyanides by Zhang, Zuxiao, Tang, Xiaojun, Dolbier, William R

“…Using visible-light photoredox conditions, difluoromethylation and 1,1-difluoroalkylation of biphenyl isocyanides have allowed the synthesis of a series of…”
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Photoredox Catalyzed Intramolecular Fluoroalkylarylation of Unactivated Alkenes by Zhang, Zuxiao, Martinez, Henry, Dolbier, William R

“…The first example of photoredox catalyzed difluoromethylation of unactivated alkenes coupled with C–C bond formation to an aryl ring is reported. The reactions…”
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Photoredox-Catalyzed Intramolecular Difluoromethylation of N‑Benzylacrylamides Coupled with a Dearomatizing Spirocyclization: Access to CF2H‑Containing 2‑Azaspiro[4.5]deca-6,9-diene-3,8-diones by Zhang, Zuxiao, Tang, Xiao-Jun, Dolbier, William R

“…A visible light-mediated difluoromethylation of N-benzylacrylamides with HCF2SO2Cl as the HCF2 radical precursor is described. The reaction incorporates a…”
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Zinc 1,1,2,2-Tetrafluoroethanesulfinate: A Synthetically Useful Oxidative and Photoredox Source of the 1,1,2,2-Tetrafluoroethyl Radical by Li, Xinjin, Majumder, Satyajit, Tang, Xiaojun, Dolbier, William R.

“…1,1,2,2-Tetrafluoroethyl-containing molecules are of potential importance in drug discovery, but the efficient synthesis of such compounds is still relatively…”
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Visible‐Light‐Induced Three‐Component Tetrafluoroethyl‐heteroarylation of Alkenes with 1,1,2,2‐Tetrafluoroethanesulfonyl Chloride and Quinoxalin‐2(1H)‐ones by Li, Xinjin, Dolbier, William R.

“…1,1,2,2‐Tetrafluoroethyl‐containing compounds are valuable structures due to their unique physicochemical properties, which have increasing potential…”
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Ni/Ir‐Catalyzed Photoredox Decarboxylative Coupling of S‐Substituted Thiolactic Acids with Heteroaryl Bromides: Short Synthesis of Sulfoxaflor and Its SF5 Analog by Kanishchev, Oleksandr S., Dolbier, William R.

“…Metallaphotoredox cross‐coupling reactions have recently emerged as a powerful tool for the construction of C(sp2)−C(sp3) bonds between alkyl chains and…”
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Preparation of Pentafluorosulfanyl (SF5) Pyrrole Carboxylic Acid Esters by Dolbier, William R, Zheng, Zhaoyun

“…Pyrrole derivatives bearing a pentafluorosulfanyl group are currently unknown. In this paper, a facile preparation of SF5-substituted pyrrole carboxylic acid…”
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Nucleophilic Perfluoroalkylation of Aldehydes, Ketones, Imines, Disulfides, and Diselenides by Pooput, Chaya, Dolbier, William R, Médebielle, Maurice

“…Using a procedure analogous to that developed for nucleophilic trifluoromethylation, the perfluoroalkyl anion reagents created by mixing C2F5I and n-C4F9I with…”
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Chloro, difluoromethylation and chloro, carbomethoxydifluoromethylation: reaction of radicals derived from RfSO2Cl with unactivated alkenes under metal-free conditions by Thomoson, Charles S, Tang, Xiao-Jun, Dolbier, Jr, William R

“…Difluoromethyl and carbomethoxydifluoromethyl radicals were generated from their respective sulfonyl chlorides under mild, metal-free conditions leading to…”
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Structure, Synthesis, and Chemical Reactions of Fluorinated Cyclopropanes and Cyclopropenes by Dolbier, William R, Battiste, Merle A

“…Fluorinated cyclopropanes will be defined as cyclopropane-containing compounds that bear at least one fluorine substituent on the cyclopropane ring. Dolbier…”
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Methyl 2,2-Difluoro-2-(fluorosulfonyl)acetate, a Difluorocarbene Reagent with Reactivity Comparable to That of Trimethylsilyl 2,2-Difluoro-2-(fluorosulfonyl)acetate (TFDA) by Eusterwiemann, Steffen, Martinez, Henry, Dolbier, William R

“…Under specific high concentration, high temperature conditions, methyl 2,2-difluoro-2-(fluorosulfonyl)acetate (MDFA) has been found to act as a very efficient…”
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A New and Efficient Method for the Synthesis of Trifluoromethylthio- and Selenoethers by Pooput, Chaya, Medebielle, Maurice, Dolbier, William R

“…A new atom-economic procedure for preparation of trifluoromethyl thio- and selenoethers is reported, wherein both halves of aryl and alkyl disulfides and…”
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Friedel−Crafts Reactions of 2,2-Difluorocyclopropanecarbonyl Chloride: Unexpected Ring-Opening Chemistry by Dolbier, William R, Cornett, Eric, Martinez, Henry, Xu, Wei

“…The Friedel−Crafts reactions of 2,2-difluorocyclopropanecarbonyl chloride with various arenes did not lead to the straightforward formation of the expected…”
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Structure, Reactivity, and Chemistry of Fluoroalkyl Radicals by Dolbier, William R

“…Dolbier reviews the literature of the past 20 years on the structure, reactivity, and chemistry of carbon-based, fluorine-containing free radicals in solution…”
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