Search Results - "Dolben, Emily"
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A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles
Published in PLoS pathogens (01-06-2016)“…Bacterial outer membrane vesicle (OMV)-mediated delivery of proteins to host cells is an important mechanism of host-pathogen communication. Emerging evidence…”
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2
Coculture of Staphylococcus aureus with Pseudomonas aeruginosa Drives S. aureus towards Fermentative Metabolism and Reduced Viability in a Cystic Fibrosis Model
Published in Journal of bacteriology (01-07-2015)“…The airways of patients with cystic fibrosis are colonized with diverse bacterial communities that change dynamically during pediatric years and early…”
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Analysis of Lung Microbiota in Bronchoalveolar Lavage, Protected Brush and Sputum Samples from Subjects with Mild-To-Moderate Cystic Fibrosis Lung Disease
Published in PloS one (04-03-2016)“…Individuals with cystic fibrosis (CF) often acquire chronic lung infections that lead to irreversible damage. We sought to examine regional variation in the…”
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4
Candida albicans ethanol stimulates Pseudomonas aeruginosa WspR-controlled biofilm formation as part of a cyclic relationship involving phenazines
Published in PLoS pathogens (01-10-2014)“…In chronic infections, pathogens are often in the presence of other microbial species. For example, Pseudomonas aeruginosa is a common and detrimental lung…”
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5
Links between Anr and Quorum Sensing in Pseudomonas aeruginosa Biofilms
Published in Journal of bacteriology (01-09-2015)“…In Pseudomonas aeruginosa, the transcription factor Anr controls the cellular response to low oxygen or anoxia. Anr activity is high in oxygen-limited…”
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6
Characterization and quantification of the fungal microbiome in serial samples from individuals with cystic fibrosis
Published in Microbiome (03-11-2014)“…Human-associated microbial communities include fungi, but we understand little about which fungal species are present, their relative and absolute abundances,…”
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Bacterial Outer Membrane Vesicles and Immune Modulation of the Host
Published in Membranes (Basel) (24-08-2023)“…This article reviews the role of outer membrane vesicles (OMVs) in mediating the interaction between Gram-negative bacteria and their human hosts. OMVs are…”
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8
self-lysis pathway that enhances the virulence of a pathogenic bacterium
Published in Proceedings of the National Academy of Sciences - PNAS (07-07-2015)“…In mammalian cells, programmed cell death (PCD) plays important roles in development, in the removal of damaged cells, and in fighting bacterial infections…”
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9
Unique microbial communities persist in individual cystic fibrosis patients throughout a clinical exacerbation
Published in Microbiome (01-11-2013)“…Cystic fibrosis (CF) is caused by inherited mutations in the cystic fibrosis transmembrane conductance regulator gene and results in a lung environment that is…”
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10
Use of a Multiplex Transcript Method for Analysis of Pseudomonas aeruginosa Gene Expression Profiles in the Cystic Fibrosis Lung
Published in Infection and immunity (01-10-2016)“…The discovery of therapies that modulate Pseudomonas aeruginosa virulence or that can eradicate chronic P. aeruginosa lung infections associated with cystic…”
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11
Profiling of Bacterial and Fungal Microbial Communities in Cystic Fibrosis Sputum Using RNA
Published in mSphere (08-08-2018)“…Here, we report an approach to detect diverse bacterial and fungal taxa in complex samples by direct analysis of community RNA in one step using NanoString…”
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Epoxide-Mediated CifR Repression of cif Gene Expression Utilizes Two Binding Sites in Pseudomonas aeruginosa
Published in Journal of Bacteriology (01-10-2012)“…Pseudomonas aeruginosa secretes an epoxide hydrolase virulence factor that reduces the apical membrane expression of ABC transporters such as the cystic…”
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An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung
Published in American journal of physiology. Lung cellular and molecular physiology (01-01-2018)“…The opportunistic pathogen Pseudomonas aeruginosa colonizes the lungs of susceptible individuals by deploying virulence factors targeting host defenses. The…”
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14
Acidosis potentiates the host proinflammatory interleukin-1β response to Pseudomonas aeruginosa infection
Published in Infection and immunity (01-11-2014)“…Infection by Pseudomonas aeruginosa, and bacteria in general, frequently promotes acidification of the local microenvironment, and this is reinforced by…”
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Candida albicans Ethanol Stimulates Pseudomonas aeruginosa WspR-Controlled Biofilm Formation as Part of a Cyclic Relationship Involving Phenazines: e1004480
Published in PLoS pathogens (01-10-2014)“…In chronic infections, pathogens are often in the presence of other microbial species. For example, Pseudomonas aeruginosa is a common and detrimental lung…”
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16
Analysis of Lung Microbiota in Bronchoalveolar Lavage, Protected Brush and Sputum Samples from Subjects with Mild-To-Moderate Cystic Fibrosis Lung Disease: e0149998
Published in PloS one (01-03-2016)“…Individuals with cystic fibrosis (CF) often acquire chronic lung infections that lead to irreversible damage. We sought to examine regional variation in the…”
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