Search Results - "Dolan, Ross D."

The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores by Dolan, Ross D, McSorley, Stephen T, Park, James H, Watt, David G, Roxburgh, Campbell S, Horgan, Paul G, McMillan, Donald C

“…Introduction The systemic inflammatory response has been proven to have a prognostic value. There are two methods of assessing the systemic inflammatory…”
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Computed tomography‐defined low skeletal muscle index and density in cancer patients: observations from a systematic review by McGovern, Josh, Dolan, Ross D., Horgan, Paul G., Laird, Barry J., McMillan, Donald C.

“…Background Computed tomography (CT) analysis of body composition has garnered interest as a potential prognostic tool in those with cancer. A range of…”
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The relationship between computed tomography‐derived body composition, systemic inflammatory response, and survival in patients undergoing surgery for colorectal cancer by Dolan, Ross D., Almasaudi, Arwa S., Dieu, Ly B., Horgan, Paul G., McSorley, Stephen T., McMillan, Donald C.

“…Introduction Colorectal cancer is the fourth leading cause of cancer mortality in developed countries. There is evidence supporting a disproportionate loss of…”
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Comparison of the prognostic value of ECOG-PS, mGPS and BMI/WL: Implications for a clinically important framework in the assessment and treatment of advanced cancer by Dolan, Ross D., Daly, Louise, Sim, Wei M.J., Fallon, Marie, Ryan, Aoife, McMillan, Donald C., Laird, Barry J.

“…The systemic inflammatory response is associated with the loss of lean tissue, anorexia, weakness, fatigue and reduced survival in patients with advanced…”
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CT-derived body composition and differential association with age, TNM stage and systemic inflammation in patients with colon cancer by Golder, Allan M., Ferguson, Michael, McMillan, Paul, Mansouri, David, Horgan, Paul G., Roxburgh, Campbell S., Dolan, Ross D., McGovern, Josh, McMillan, Donald C.

“…Low skeletal muscle index/density (SMI/SMD) is prevalent in cancer, adversely prognostic and associated with tumour stage and the systemic inflammatory…”
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The relationship between heart rate variability and TNM stage, co-morbidity, systemic inflammation and survival in patients with primary operable colorectal cancer by McGovern, Josh, Leadbitter, Stephen, Miller, Gillian, Hounat, Adam, Kamande, Irvine, Dolan, Ross D., Horgan, Paul G., Chang, David K., Jamieson, Nigel B., McMillan, Donald C.

“…High vagal nerve activity, reliability measured by HRV, is considered protective in cancer, reducing oxidative stress, inflammation and opposing sympathetic…”
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CT-derived body composition: Differential association with disease, age and inflammation in a retrospective cohort study by Bradley, Nicholas A, McGovern, Josh, Dolan, Ross D, Golder, Allan M, Roxburgh, Campbell S D, Guthrie, Graeme J K, McMillan, Donald C

“…Low skeletal muscle mass and density, as assessed by CT-body composition (CT-BC), are recognised to have prognostic value in non-cancer and cancer patients…”
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The relationship between the modified frailty index score (mFI-5), malnutrition, body composition, systemic inflammation and short-term clinical outcomes in patients undergoing surgery for colorectal cancer by McGovern, Josh, Grayston, Alexander, Coates, Dominic, Leadbitter, Stephen, Hounat, Adam, Horgan, Paul G, Dolan, Ross D, McMillan, Donald C

“…While the current literature suggests an association with frailty and clinical outcomes in patients undergoing surgery for colorectal cancer (CRC), the basis…”
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The relationship between frailty, nutritional status, co-morbidity, CT-body composition and systemic inflammation in patients with COVID-19 by McGovern, Josh, Al-Azzawi, Yassir, Kemp, Olivia, Moffitt, Peter, Richards, Conor, Dolan, Ross D, Laird, Barry J, McMillan, Donald C, Maguire, Donogh

“…Frailty, determined by the Canadian Study of Health and Aging-Clinical Frailty Scale (CFS), is strongly associated with clinical outcomes including mortality…”
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The prevalence and prognostic value of frailty screening measures in patients undergoing surgery for colorectal cancer: observations from a systematic review by McGovern, Josh, Dolan, Ross D, Horgan, Paul G, Laird, Barry J, McMillan, Donald C

“…Frailty is a complex multifactorial syndrome characterised by a significant increase in vulnerability and worsened health outcomes. Despite a range of proposed…”
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REVOLUTION (Routine EValuatiOn of people LivIng with caNcer)-Protocol for a prospective characterisation study of patients with incurable cancer by Patton, Rebekah, Cook, Jane, Haraldsdottir, Erna, Brown, Duncan, Dolan, Ross D, McMillan, Donald C, Skipworth, Richard J E, Fallon, Marie, Laird, Barry J A

“…There is a pressing need for a holistic characterisation of people with incurable cancer. In this group, where quality of life and improvement of symptoms are…”
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The relationship between clinicopathological variables, systemic inflammation, and CT‐derived body composition with survival in patients with advanced non‐small cell lung cancer receiving nivolumab as a second‐line treatment by Saeed, Randa, McGovern, Josh, Bench, Hugo, Dolan, Ross D., McMillan, Donald C., Cascales, Almudena

“…Background Second‐line immunotherapy is currently recognized to help only a subset of patients with advanced forms of non‐small cell lung cancer (NSCLC). The…”
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Possible dose dependent effect of perioperative dexamethasone and laparoscopic surgery on the postoperative systemic inflammatory response and complications following surgery for colon cancer by McSorley, Stephen T., Dolan, Ross D., Roxburgh, Campbell SD, Horgan, Paul G., MacKay, Graham J., McMillan, Donald C.

“…Perioperative dexamethasone is associated with attenuation of the postoperative systemic inflammatory response and fewer postoperative complications following…”
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The prevalence and prognostic value of systemic inflammation in good performance status patients with advanced, inoperable non‐small cell lung cancer receiving palliative radiotherapy: Comparison of composite ratios and cumulative scores by McGovern, Josh, O'Rourke, Fraser, Will, Sarah, Nguyen, Hanh Thi Ngoc, Cranfield, Elise, Maseland, Charlotte, MacLeod, Nicholas, Maclay, John D., Laird, Barry J., Dolan, Ross D., McMillan, Donald C.

“…Introduction The present study sought to examine the relationships between systemic inflammatory composite ratios/cumulative scores, magnitude of systemic…”
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Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series by Vagnildhaug, Ola Magne, Balstad, Trude R., Ottestad, Inger, Bye, Asta, Greil, Christine, Arends, Jann, Baracos, Vickie, Brown, Leo R., Dajani, Olav F., Dolan, Ross D., Fallon, Marie, Fraser, Eilidh, Grzyb, Aleksandra, Hjermstad, Marianne J., Jakobsen, Gunnhild, Kaasa, Stein, McDonald, James, Philips, Iain, Sayers, Judith, Simpson, Melanie R., Sousa, Mariana S., Skipworth, Richard J.E., Laird, Barry J.A., Solheim, Tora S.

“…There is no consensus on the optimal endpoint(s) in cancer cachexia trials. Endpoint variation is an obstacle when comparing interventions and their clinical…”
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Quality of life endpoints in cancer cachexia clinical trials: Systematic review 3 of the cachexia endpoints series by Hjermstad, Marianne J., Jakobsen, Gunnhild, Arends, Jann, Balstad, Trude R., Brown, Leo R., Bye, Asta, Coats, Andrew J.S., Dajani, Olav F., Dolan, Ross D., Fallon, Marie T., Greil, Christine, Grzyb, Alexandra, Kaasa, Stein, Koteng, Lisa H., May, Anne M., McDonald, James, Ottestad, Inger, Philips, Iain, Roeland, Eric J., Sayers, Judith, Simpson, Melanie R., Skipworth, Richard J.E., Solheim, Tora S., Sousa, Mariana S., Vagnildhaug, Ola M., Laird, Barry J.A.

“…The use of patient‐reported outcomes (PROMs) of quality of life (QOL) is common in cachexia trials. Patients' self‐report on health, functioning, wellbeing,…”
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The Relationship between Liver Volume, Clinicopathological Characteristics and Survival in Patients Undergoing Resection with Curative Intent for Non-Metastatic Colonic Cancer by McGovern, Josh, Mackay, Charles, Freireich, Rhiannon, Golder, Allan M, Dolan, Ross D, Horgan, Paul G, Holroyd, David, Jamieson, Nigel B, McMillan, Donald C

“…The prognostic value of CT-derived liver volume in terms of cancer outcomes is not clear. The aim of the present study was to examine the relationship between…”
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Body weight and composition endpoints in cancer cachexia clinical trials: Systematic Review 4 of the cachexia endpoints series by Brown, Leo R., Sousa, Mariana S., Yule, Michael S., Baracos, Vickie E., McMillan, Donald C., Arends, Jann, Balstad, Trude R., Bye, Asta, Dajani, Olav, Dolan, Ross D., Fallon, Marie T., Greil, Christine, Hjermstad, Marianne J., Jakobsen, Gunnhild, Maddocks, Matthew, McDonald, James, Ottestad, Inger O., Phillips, Iain, Sayers, Judith, Simpson, Melanie R., Vagnildhaug, Ola M., Solheim, Tora S., Laird, Barry J.A., Skipworth, Richard J.E.

“…Significant variation exists in the outcomes used in cancer cachexia trials, including measures of body composition, which are often selected as primary or…”
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Biomarker endpoints in cancer cachexia clinical trials: Systematic Review 5 of the cachexia endpoint series by Yule, Michael S., Thompson, Joshua, Leesahatsawat, Khachonphat, Sousa, Mariana S., Anker, Stefan D., Arends, Jann, Balstad, Trude R., Brown, Leo R., Bye, Asta, Dajani, Olav, Fallon, Marie, Hjermstad, Marianne J., Jakobsen, Gunnhild, McDonald, James, McGovern, Josh, Roeland, Eric J., Sayers, Judith, Skipworth, Richard J.E., Ottestad, Inger O., Philips, Iain, Simpson, Melanie R., Solheim, Tora S., Vagnildhaug, Ola Magne, McMillan, Donald, Laird, Barry J.A., Dolan, Ross D.

“…Regulatory agencies require evidence that endpoints correlate with clinical benefit before they can be used to approve drugs. Biomarkers are often considered…”
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The role of the systemic inflammatory response in predicting outcomes in patients with advanced inoperable cancer: Systematic review and meta -analysis by Dolan, Ross D, McSorley, Stephen T, Horgan, Paul G, Laird, Barry, McMillan, Donald C

“…Highlights • Provides comprehensive evidence for the prognostic role of the SIR in advanced cancer. • This review will prove to be clinically very useful in…”
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