Search Results - "Dolan, Philip"

Laser writing of coherent colour centres in diamond by Chen, Yu-Chen, Salter, Patrick S., Knauer, Sebastian, Weng, Laiyi, Frangeskou, Angelo C., Stephen, Colin J., Ishmael, Shazeaa N., Dolan, Philip R., Johnson, Sam, Green, Ben L., Morley, Gavin W., Newton, Mark E., Rarity, John G., Booth, Martin J., Smith, Jason M.

“…A negatively charged nitrogen–vacancy centre — a promising quantum light source — is created in diamond by laser writing (with pulses with a central wavelength…”
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Complete determination of the orientation of NV centers with radially polarized beams by Dolan, Philip R, Li, Xiangping, Storteboom, Jelle, Gu, Min

“…In this paper, we report on the precise determination of the orientation of NV centers by imaging with a radially polarized beam. Vectorial Debye theory is…”
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Topographic control of open-access microcavities at the nanometer scale by Trichet, Aurélien A P, Dolan, Philip R, Coles, David M, Hughes, Gareth M, Smith, Jason M

“…Open-access optical microcavities are emerging as an original tool for light-matter studies thanks to their intrinsic tunability and the direct access to the…”
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A Caspase Cleaved Form of Tau Is Preferentially Degraded through the Autophagy Pathway by Dolan, Philip J., Johnson, Gail V.W.

“…The microtubule-associated protein tau plays a central role in the pathogenesis of Alzheimer disease (AD) and abnormally accumulates as neurofibrillary…”
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Histone deacetylase 6 interacts with the microtubule-associated protein tau by Ding, Huiping, Dolan, Philip J, Johnson, Gail V.W

“…Histone deacetylase 6 (HDAC6), a unique cytoplasmic deacetylase, likely plays a role in neurodegeneration by coordinating cell responses to abnormal protein…”
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Truncated tau and Aβ cooperatively impair mitochondria in primary neurons by Quintanilla, Rodrigo A, Dolan, Philip J, Jin, Youngnam N, Johnson, Gail V.W

“…Abstract Mitochondrial dysfunction is likely a significant contributing factor to Alzheimer disease pathogenesis, and both amyloid peptide (Aβ) and…”
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Caspase-cleaved Tau Expression Induces Mitochondrial Dysfunction in Immortalized Cortical Neurons: IMPLICATIONS FOR THE PATHOGENESIS OF ALZHEIMER DISEASE by Quintanilla, Rodrigo A, Matthews-Roberson, Tori A, Dolan, Philip J, Johnson, Gail V.W

“…In Alzheimer disease (AD) mitochondrial abnormalities occur early in the pathogenic process and likely play a significant role in disease progression. Tau is a…”
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The toxicity of tau in Alzheimer disease: turnover, targets and potential therapeutics by Pritchard, Susanne M., Dolan, Philip J., Vitkus, Alisa, Johnson, Gail V.W.

“…•  Introduction •  Pathological modifications of tau ‐  Tau phosphorylation ‐  Tau truncation ‐  NFTs are not the primary toxic species •  Tau turnover and…”
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Controlling the emission from semiconductor quantum dots using ultra-small tunable optical microcavities by Di, Ziyun, Jones, Helene V, Dolan, Philip R, Fairclough, Simon M, Wincott, Matthew B, Fill, Johnny, Hughes, Gareth M, Smith, Jason M

“…We report the control of spontaneous emission from CdSe/ZnS core-shell quantum dots coupled to novel open-access optical microcavities. The cavities are…”
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The Low Density Lipoprotein Receptor-related Protein 6 Interacts with Glycogen Synthase Kinase 3 and Attenuates Activity by Mi, Kaihong, Dolan, Philip J., Johnson, Gail V.W.

“…Glycogen synthase kinase 3 (GSK3) is a widely expressed Ser/Thr protein kinase that phosphorylates numerous substrates. This large number of substrates…”
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Diamond photonics for distributed quantum networks by Johnson, Sam, Dolan, Philip R., Smith, Jason M.

“…The distributed quantum network, in which nodes comprising small but well-controlled quantum states are entangled via photonic channels, has in recent years…”
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2A4 binds soluble and insoluble light chain aggregates from AL amyloidosis patients and promotes clearance of amyloid deposits by phagocytosis by Renz, Mark, Torres, Ronald, Dolan, Philip J., Tam, Stephen J., Tapia, Jose R., Li, Lauri, Salmans, Joshua R., Barbour, Robin M., Shughrue, Paul J., Nijjar, Tarlochan, Schenk, Dale, Kinney, Gene G., Zago, Wagner

“…Amyloid light chain (AL) amyloidosis is characterized by misfolded light chain (LC) (amyloid) deposition in various peripheral organs, leading to progressive…”
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Diffusion-driven continuous-wave-pumped organic dye lasers by Coles, David M., Trichet, Aurélien A. P., Dolan, Philip R., Taylor, Robert A., Vallance, Claire, Smith, Jason M.

“…We report on the realisation of ultra‐small‐mode‐volume tunable dye lasers based on hemispherical open microcavities. The cavity mode volume is of the order of…”
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Anti-Mcam Monoclonal Antibody PRX003 Inhibits the Unique Migratory Potential of Pathogenic IL-17–Producing T Cells by Flanagan, Kenneth, Tam, Stephen J, Li, Lauri, Dolan, Philip J, Barbour, Robin M, Higaki, Jeffrey N, Liu, Yue, Nijjar, Tarlochan, Skov, Michael, Zago, Wagner, Yednock, Ted A, Kinney, Gene F, Ness, Dan

“…Rationale Melanoma cell adhesion molecule (MCAM) expression on a small subset of memory CD4+/CD8+ T cells defines their ability to secrete IL-17 and identifies…”
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Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356 by Dolan, Philip J., Jin, Youngnam N., Hwang, Woong, Johnson, Gail V.W.

“…► VCP levels are decreased in Alzheimer disease brain. ► VCP knockdown in neurons decreases total soluble tau levels. ► VCP knockdown increases the levels of…”
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Optical properties of a single-colour centre in diamond with a green zero-phonon line by Smith, Jason M, Grazioso, Fabio, Patton, Brian R, Dolan, Philip R, Markham, Matthew L, Twitchen, Daniel J

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Gain Spectroscopy of Solution-Based Semiconductor Nanocrystals in Tunable Optical Microcavities by Patel, Robin K., Trichet, Aurélien A. P., Coles, David M., Dolan, Philip R., Fairclough, Simon M., Leontiadou, Marina A., Tsang, S. C. Edman, Binks, David J., Jang, Eunjoo, Jang, Hyosook, Taylor, Robert A., Smith, Jason M.

“…The lasing behavior of solution‐based colloidal quantum dots within an open microcavity is reported. The small size and wide tunability of the cavity provide…”
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Optical properties of single crystal diamond microfilms fabricated by ion implantation and lift-off processing by Patton, Brian R., Dolan, Philip R., Grazioso, Fabio, Wincott, Matthew B., Smith, Jason M., Markham, Matthew L., Twitchen, Daniel J., Zhang, Yanfeng, Gu, Erdan, Dawson, Martin D., Fairchild, Barbara A., Greentree, Andrew D., Prawer, Steven

“…We report the fabrication and optical characterisation of ~1 μm thick films of single crystal diamond prepared by an ion implantation and lift-off process. A…”
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Spectroscopy: Gain Spectroscopy of Solution-Based Semiconductor Nanocrystals in Tunable Optical Microcavities (Advanced Optical Materials 2/2016) by Patel, Robin K., Trichet, Aurélien A. P., Coles, David M., Dolan, Philip R., Fairclough, Simon M., Leontiadou, Marina A., Tsang, S. C. Edman, Binks, David J., Jang, Eunjoo, Jang, Hyosook, Taylor, Robert A., Smith, Jason M.

“…J. M. Smith and co‐workers demonstrate a new design of miniature tunable dye laser using solution‐based colloidal CdSe/CdS core/shell quantum dots in open…”
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The role of tau kinases in Alzheimer's disease by Dolan, Philip J, Johnson, Gail V W

“…A principal feature of the progression of Alzheimer's disease (AD) is the appearance of aberrant phosphorylation of the microtubule-associated protein tau in…”
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