Search Results - "Doklady. Biochemistry and biophysics"

Frequency-dependent effect of insulin on myocardial contractility in active ground squirrel Citellus undulatus in different seasons by Nakipova, O V, Andreeva, L A, Chumaeva, N A, Anufriev, A I, Kosarskii, L S, Kolaeva, S G, Kukushkin, N I, Solomonov, N G

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Functional Analysis of Coilin in Virus Resistance and Stress Tolerance of Potato Solanum tuberosum using CRISPR-Cas9 Editing by Makhotenko, A. V., Khromov, A. V., Snigir, E. A., Makarova, S. S., Makarov, V. V., Suprunova, T. P., Kalinina, N. O., Taliansky, M. E.

“…The role of the nuclear protein coilin in the mechanisms of resistance of potato Solanum tuberosum cultivar Chicago to biotic and abiotic stresses was studied…”
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Immunoliposomes As a Promising Antiviral Agent against SARS-CoV-2 by Bobik, T. V., Simonova, M. A., Rushkevich, N. U., Kostin, N. N., Skryabin, G. A., Knorre, V. D., Schulga, A. A., Konovalova, E. V., Proshkina, G. M., Gabibov, A. G., Deev, S. M.

“…According to the World Health Organization, as of January 3, 2020 to September 13, 2023, there were approximately 23 million confirmed cases of COVID-19…”
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PRPF19 mRNA Encodes a Small Open Reading Frame That Is Important for Viability of Human Cells by Shepelev, N. M., Kurochkina, A. O., Dontsova, O. A., Rubtsova, M. P.

“…High-throughput ribosome profiling demonstrates the translation of thousands of small open reading frames located in the 5′ untranslated regions of messenger…”
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HspBP1 in Complex with the Peptide of the Innate Immunity Protein Tag7 is Able to Lyse Tumor Cells Carrying TNFR1 Receptor by Romanova, E. A., Yurkina, D. M., Yashin, D. V., Sashchenko, L. P., Georgiev, G. P.

“…The search for new cytotoxic agents capable of lysing tumor cells is an important task in the fight against cancer. Here we have shown that the HspBP1 protein,…”
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The Level of Anti-Viral Antigen-Specific Antibodies to EBNA-1 in the Serum of MS Patients Does not Depend on the Severity of the Disease by Ovchinnikova, L. A., Dzhelad, S. S., Simaniv, T. O., Zakharova, M. N., Gabibov, A. G., Lomakin, Y. A.

“…Multiple sclerosis (MS) is an autoimmune neurodegenerative disease leading to inevitable disability and primarily affecting the young and middle-aged…”
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Dichotomic Role of Low-Concentration EGCG in the Oxaliplatin Sensitivity of Colorectal Cancer Cells by Wang, Zhiyong, Wang, Min, Huang, Jiahao, Lin, Mao, Wei, Pei

“…Although epigallocatechin-3-gallate (EGCG) can potentiate chemotherapeutic drugs at high concentrations, its clinical translation is hampered by exceeding…”
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Interaction of mRNA with the C-Terminal Domain of PCID2, a Subunit of the TREX-2 Complex, Is Required for Its Export from the Nucleus to the Cytoplasm in Drosophila melanogaster by Vdovina, Yu. A., Georgieva, S. G., Kopytova, D. V.

“…Following the transcription step, the newly synthesized mRNA is exported from the nucleus to the cytoplasm and further to the translation site. The TREX-2…”
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Enhancing Human Glycoprotein Hormones Production in CHO Cells Using Heterologous Beta-Chain Signal Peptides by Sinegubova, M. V., Kolesov, D. E., Dayanova, L. K., Vorobiev, I. I., Orlova, N. A.

“…We studied the influence of heterologous signal peptides in the β-chains of glycoprotein hormones on the biosynthesis of these hormones in a transiently…”
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TREX-2-ORC Complex of D. melanogaster Participates in Nuclear Export of Histone mRNA by Kurshakova, M. M., Yakusheva, Y. A., Georgieva, S. G.

“…The TREX-2-ORC protein complex of D. melanogaster is necessary for the export of the bulk of synthesized poly(A)-containing mRNA molecules from the nucleus to…”
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Neuronal and Muscle Differentiation of Mammalian Cells Is Accompanied by a Change in PHF10 Isoform Expression by Bayramova, D. O., Azieva, A. M., Feoktistov, A. V., Georgieva, S. G., Soshnikova, N. V.

“…The PBAF chromatin remodeling complex of the SWI/SNF family plays a critical role in the regulation of gene expression during tissue differentiation and…”
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Parameters of Cell Death and Proliferation of Prostate Cancer Cells with Altered Expression of Myosin 1C Isoforms by Solomatina, E. S., Nishkomaeva, E. N., Kovaleva, A. V., Tvorogova, A. V., Potashnikova, D. M., Saidova, A. A.

“…Myosin 1C is a monomeric myosin motor with a truncated tail domain. Such motors are referred as slow “tension sensors.” Three isoforms of myosin 1C differ in…”
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The Study of TRPV1 Channels of the Central Nervous System and Their Effect on Anxiety in ICR Mice by Pavlov, V. M., Fedotova, A. Yu, Andreev, Y. A., Palikov, V. A., Dyachenko, I. A.

“…The TRPV1 channel is actively involved in various neuronal processes and is found in various structures of the nervous system, including peripheral and central…”
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Development of a Panel of Biomarkers for Differential Diagnosis of Multiple Sclerosis by Ovchinnikova, L. A., Dzhelad, S. S., Simaniv, T. O., Zakharova, M. N., Lomakin, Y. A., Gabibov, A. G., Illarioshkin, S. N.

“…Abstract— Demyelinating diseases are a group of heterogeneous pathologies that affect the nervous system and reduce the quality of life. One of such diseases…”
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Are the Goals of Therapy Achievable in Patients with Rheumatoid Arthritis Receiving Upadacitinib in Real Clinical Practice? by Amirdzhanova, V. N., Karateev, A. E., Pogozheva, E. Yu, Filatova, E. S., Samigullina, R. R., Mazurov, V. I., Anoshenkova, O. N., Lapkina, N. A., Baranov, A. A., Grineva, T. Yu, Lila, A. M., Nasonov, E. L.

“…The aim of the study was to evaluate the effectiveness of UPA in RA patients in real clinical practice after 3 and 6 months of therapy. The study included 63…”
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Structure Analysis of the MatA Locus of Sexual Compatibility in the Edible Mushroom Pleurotus ostreatus by Shnyreva, A. V., Shnyreva, A. A.

“…The edible oyster mushroom Pleurotus ostreatus is one of the most cultivated species worldwide. Morphogenesis associated with the maturation of fruit bodies is…”
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Effects of Overexpression of Specific Subunits SAYP, BAP170 of the Chromatin Remodeling Complex in Drosophila Melanogaster by Chmykhalo, V K, Shidlovskii, Y V, Lebedeva, L A, Schedl, P, Giordano, E

“…The phenotypic manifestations of increased expression of the Bap170 and e(y)3 (SAYP) genes in D. melanogaster were analyzed. Using the wing disc model, we show…”
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IGFBP6 Modulates Proteostasis by Activating ATF4 Targets and Reducing ER Retrotranslocon Expression by Kolodeeva, O E, Antipenko, I D, Fatkulin, A A, Yakhina, M R, Makarova, J A

“…Reduced expression of the IGFBP6 protein leads to an increase in the metastatic potential of breast cancer (BC) cells. The level of protein synthesis in tumor…”
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The Role of Changes in the Redox Status in the Pathogenesis of Chronic Lymphocytic Leukemia by Osikov, M V, Korobkin, E A, Fedosov, A A, Sineglazova, A V

“…Chronic lymphocytic leukemia is a hemoblastosis of CD5 B lymphocytes with lymphocytosis, damage to the lymphatic organs, occurring in the older age group, the…”
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Synthesis and Antitumour Activity of Hybrid Compounds Based on 4-Aminophenylarsonic Acid and Spatially Hindered Phenols by Bukharov, S V, Rakhmatullin, R R, Zamaletdinova, D M, Bogdanov, A V, Voloshina, A D

“…One of the main modern approaches to the creation of effective drugs is the design of new biologically active substances containing two or more pharmacophore…”
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