Search Results - "Doiron, Nicholas"
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RNA-Seq analysis validates the use of culture-derived Trypanosoma brucei and provides new markers for mammalian and insect life-cycle stages
Published in BMC genomics (02-04-2018)“…Trypanosoma brucei brucei, the parasite causing Nagana in domestic animals, is closely related to the parasites causing sleeping sickness, but does not infect…”
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TAC102 Is a Novel Component of the Mitochondrial Genome Segregation Machinery in Trypanosomes
Published in PLoS pathogens (01-05-2016)“…Trypanosomes show an intriguing organization of their mitochondrial DNA into a catenated network, the kinetoplast DNA (kDNA). While more than 30 proteins…”
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Trypanosomal TAC40 constitutes a novel subclass of mitochondrial β-barrel proteins specialized in mitochondrial genome inheritance
Published in Proceedings of the National Academy of Sciences - PNAS (27-05-2014)“…Mitochondria cannot form de novo but require mechanisms allowing their inheritance to daughter cells. In contrast to most other eukaryotes Trypanosoma brucei…”
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Correction: TAC102 Is a Novel Component of the Mitochondrial Genome Segregation Machinery in Trypanosomes
Published in PLoS pathogens (01-07-2016)“…[This corrects the article DOI: 10.1371/journal.ppat.1005586.]…”
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Solitary confinement as state harm: Reimagining sentencing in light of dynamic censure and state blame
Published in Punishment & society (01-01-2024)“…The continuous perpetration of unjustified harms by the carceral state through its use of solitary confinement justifies the creation of a novel process of…”
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The nuclear RNA binding protein RBP33 influences mRNA and spliced leader RNA abundance in Trypanosoma brucei
Published in Molecular and biochemical parasitology (01-03-2017)“…RNA recognition motif (RRM) containing proteins are important regulators of gene expression in trypanosomes. Here we expand our current knowledge on the…”
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Zinc finger nuclease technology: A stable tool for high efficiency transformation in bloodstream form T. brucei
Published in Molecular and biochemical parasitology (01-04-2017)“…•Zinc finger nuclease system established in Trypanosoma brucei.•Cell lines that inducibly express zinc finger nucleases are stable.•Transfection efficiency…”
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Trypanosomal TAC40 constitutes a novel subclass of mitochondrial [Beta]-barrel proteins specialized in mitochondrial genome inheritance
Published in Proceedings of the National Academy of Sciences - PNAS (27-05-2014)“…Mitochondria cannot form de novo but require mechanisms allowing their inheritance to daughter cells. In contrast to most other eukaryotes Trypanosoma brucei…”
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