Search Results - "Doillon, Charles J."

The stimulation of angiogenesis and collagen deposition by copper by Gérard, Catherine, Bordeleau, Louis-Jean, Barralet, Jake, Doillon, Charles J

“…Abstract Copper is known to trigger endothelial cells towards angiogenesis. Different approaches have been investigated to develop vascularisation in…”
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Preparation of ready-to-use, storable and reconstituted type I collagen from rat tail tendon for tissue engineering applications by Doillon, Charles J, Mantovani, Diego, Rajan, Navneeta, Habermehl, Jason, Coté, Marie-France

“…Collagen is a widely investigated extracellular matrix material with extensive potentials in the field of tissue engineering. This protocol describes a method…”
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A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene by Gobeil, Stephane, Zhu, Xiaochun, Doillon, Charles J, Green, Michael R

“…Metastasis suppressor genes inhibit one or more steps required for metastasis without affecting primary tumor formation. Due to the complexity of the…”
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Collagen Biomineralization In Vivo by Sustained Release of Inorganic Phosphate Ions by Habibovic, Pamela, Bassett, David C., Doillon, Charles J., Gerard, Catherine, McKee, Marc D., Barralet, Jake E.

“…A new strategy for mineralized tissue formation in vivo is presented based on localized sustained delivery of inorganic orthophosphate (Pi) sufficient to…”
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Facilitating tissue infiltration and angiogenesis in a tubular collagen scaffold by Gérard, Catherine, Doillon, Charles J.

“…Among different strategies to provide blood supply to tissue‐engineered devices and implants, the use of arteriovenous loops and bundles has been proposed. The…”
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Computational modeling of adherent cell growth in a hollow-fiber membrane bioreactor for large-scale 3-D bone tissue engineering by Mohebbi-Kalhori, Davod, Behzadmehr, Amin, Doillon, Charles J., Hadjizadeh, Afra

“…The use of hollow-fiber membrane bioreactors (HFMBs) has been proposed for three-dimensional bone tissue growth at the clinical scale. However, to achieve an…”
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Functional Human Corneal Equivalents Constructed from Cell Lines by Griffith, May, Osborne, Rosemarie, Munger, Rejean, Xiong, Xiaojuan, Doillon, Charles J., Noelani L. C. Laycock, Hakim, Malik, Song, Ying, Watsky, Mitchell A.

“…Human corneal equivalents comprising the three main layers of the cornea (epithelium, stroma, and endothelium) were constructed. Each cellular layer was…”
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Bioactive Polymer Fibers to Direct Endothelial Cell Growth in a Three-Dimensional Environment by Hadjizadeh, Afra, Doillon, Charles J, Vermette, Patrick

“…This study reports the fabrication of bioactive polymer fibers onto which signaling molecules can control and direct cell responses. To encourage and control…”
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Angiogenic response of endothelial cells seeded dispersed versus on beads in fibrin gels by MARTINEAU, Laurie, DOILLON, Charles J

“…Induction of an inter-connected microvessel network in a tissue-engineered construct prior to implantation may be an alternative to improve the success rate of…”
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Three-dimensional Culture System as a Model for Studying Cancer Cell Invasion Capacity and Anticancer Drug Sensitivity by DOILLON, Charles J, GAGNON, Edith, PARADIS, Renée, KOUTSILIERIS, Michael

“…Background: Three-dimensional (3-D) culture systems that simulate the tumor extracellular microenvironment may be appropriate to test cancer cell potential for…”
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Directional migration of endothelial cells towards angiogenesis using polymer fibres in a 3D co-culture system by Hadjizadeh, Afra, Doillon, Charles J.

“…Development of an in vitro prevascularized scaffold is of great importance to produce vascularization in tissue‐engineered devices and for other clinical…”
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Angiogenesis in calcium phosphate scaffolds by inorganic copper ion release by Barralet, Jake, Gbureck, Uwe, Habibovic, Pamela, Vorndran, Elke, Gerard, Catherine, Doillon, Charles J

“…Angiogenesis in a tissue-engineered device may be induced by incorporating growth factors (e.g., vascular endothelial growth factor [VEGF]), genetically…”
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Osteoconduction and osteoinduction of low-temperature 3D printed bioceramic implants by Habibovic, Pamela, Gbureck, Uwe, Doillon, Charles J, Bassett, David C, van Blitterswijk, Clemens A, Barralet, Jake E

“…Abstract Rapid prototyping is a valuable implant production tool that enables the investigation of individual geometric parameters, such as shape, porosity,…”
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Perfluorocarbon Emulsions Cytotoxic Effects on Human Fibroblasts and Effect of Aging on Particle Size Distribution by Centis, Valérie, Doillon, Charles J., Vermette, Patrick

“…:  The purpose of this study was to characterize emulsion preparations made of perfluorooctyl bromide (PFOB) and egg yolk phospholipid (EYP) and their…”
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Newly identified interfibrillar collagen crosslinking suppresses cell proliferation and remodelling by Marelli, Benedetto, Le Nihouannen, Damien, Hacking, S. Adam, Tran, Simon, Li, Jingjing, Murshed, Monzur, Doillon, Charles J, Ghezzi, Chiara E, Zhang, Yu Ling, Nazhat, Showan N, Barralet, Jake E

“…Abstract Copper is becoming recognised as a key cation in a variety of biological processes. Copper chelation has been studied as a potential anti-angiogenic…”
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Inhibition of 17beta-hydroxysteroid dehydrogenase type 7 modulates breast cancer protein profile and enhances apoptosis by down-regulating GRP78 by Wang, Xiao-Qiang, Aka, Juliette A., Li, Tang, Xu, Dan, Doillon, Charles J., Lin, Sheng-Xiang

“…•Confirming the over-expression of 17β-HSD7 in primary and progressive Luminal subtype A breast cancer with TCGA cohort.•Suppression of 17β-HSD7…”
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In vitro interactions between mammary fibroblasts (Hs 578Bst) and cancer epithelial cells (MCF-7) modulate aromatase, steroid sulfatase and 17β-hydroxysteroid dehydrogenases by Wang, Xiaoqiang, Sang, Xiaoye, Diorio, Caroline, Lin, Sheng-Xiang, Doillon, Charles J.

“…•2D and 3D co-cultures with MCF-7 and Hs578Bst cells mimic intratumoral steroidogenesis.•Paracrine and intracrine manners were demonstrated in co-culture…”
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Synergistic control of sex hormones by 17β-HSD type 7: a novel target for estrogen-dependent breast cancer by Wang, Xiaoqiang, Gérard, Catherine, Thériault, Jean-François, Poirier, Donald, Doillon, Charles J, Lin, Sheng-Xiang

“…17β-hydroxysteroid dehydrogenase (17β-HSD) type 1 is known as a critical target to block the final step of estrogen production in estrogen-dependent breast…”
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Effect of Sterilization on Non-woven Polyethylene Terephthalate Fiber Structures for Vascular Grafts by Dimitrievska, Sashka, Petit, Alain, Doillon, Charles J., Epure, Laura, Ajji, Abdellah, Yahia, L'Hocine, Bureau, Martin N.

“…Non‐woven polyethylene terephthalate (PET) fibers produced via melt blowing and compounded into a 6 mm diameter 3D tubular scaffold were developed with artery…”
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Denatured collagen as support for a FGF-2 delivery system: physicochemical characterizations and in vitro release kinetics and bioactivity by Côté, Marie-France, Laroche, Gaetan, Gagnon, Edith, Chevallier, Pascale, Doillon, Charles J

“…Collagen-based materials have scaffold properties to support bioactive molecules such as growth factor (GF). Gelatin, a denatured collagen, may have also some…”
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