Search Results - "Doi, Takahiro S."

Absence of Tumor Necrosis Factor Rescues RelA-Deficient Mice from Embryonic Lethality by Doi, Takahiro S., Marino, Michael W., Takahashi, Toshitada, Yoshida, Toshimichi, Sakakura, Teruyo, Old, Lloyd J., Obata, Yuichi

“…Mice lacking the RelA (p65) subunit of NF-κ B die between days 14 and 15 of embryogenesis because of massive liver destruction. Fibroblasts and macrophages…”
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p100, a precursor of NF-κB2, inhibits c-Rel and reduces the expression of IL-23 in dendritic cells by Mise-Omata, Setsuko, Obata, Yuichi, Doi, Takahiro S

“…Nuclear factor κB regulates various genes involved in the immune response, inflammation, cell survival, and development. NF-κB activation is controlled by…”
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A Proximal κB Site in the IL-23 p19 Promoter Is Responsible for RelA- and c-Rel-Dependent Transcription by Mise-Omata, Setsuko, Kuroda, Etsushi, Niikura, Junko, Yamashita, Uki, Obata, Yuichi, Doi, Takahiro S.

“…IL-23 is a heterodimeric cytokine composed of a unique p19 subunit and a common p40 subunit is shared with IL-12. IL-23 promotes the inflammatory response by…”
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Murine Delta Homologue, mDelta1, Expressed on Feeder Cells Controls Cellular Differentiation by Mizutani, Keigo, Matsubayashi, Tadashi, Iwase, Shigeru, Doi, Takahiro S., Kasai, Kenji, Yazaki, Makoto, Wada, Yoshiro, Takahashi, Toshitada, Obata, Yuichi

“…The Delta/Serrate-Notch pathway is involved in intercellular signaling that controls cell fate during the development of invertebrates and vertebrates. Delta…”
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Transient strong reduction of PTEN expression by specific RNAi induces loss of adhesion of the cells by Mise-Omata, Setsuko, Obata, Yuichi, Iwase, Shigeru, Mise, Nathan, Doi, Takahiro S.

“…The tumor suppressor gene pten encodes a lipid phosphatase that dephosphorylates D3 of phosphatidylinositol(3,4,5)trisphosphate, producing…”
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The NF-κB RelA Subunit Confers Resistance to Leishmania major by Inducing Nitric Oxide Synthase 2 and Fas Expression but Not Th1 Differentiation by Mise-Omata, Setsuko, Kuroda, Etsushi, Sugiura, Tsutomu, Yamashita, Uki, Obata, Yuichi, Doi, Takahiro S.

“…Although the NF-κB transcription factors participate in both innate and adaptive immune responses, little is known about the role of the RelA subunit because…”
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NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses by Doi, T S, Takahashi, T, Taguchi, O, Azuma, T, Obata, Y

“…To investigate the function of NF-kappa B RelA (p65), we generated mice deficient in this NF-kappa B family member by homologous recombination. Mice lacking…”
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A proximal kappaB site in the IL-23 p19 promoter is responsible for RelA- and c-Rel-dependent transcription by Mise-Omata, Setsuko, Kuroda, Etsushi, Niikura, Junko, Yamashita, Uki, Obata, Yuichi, Doi, Takahiro S

“…IL-23 is a heterodimeric cytokine composed of a unique p19 subunit and a common p40 subunit is shared with IL-12. IL-23 promotes the inflammatory response by…”
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p300/CBP-Dependent and -Independent Transcriptional Interference between NF-κB RelA and p53 by Ikeda, Akiko, Sun, Xiangao, Li, Yan, Zhang, Yong-kang, Eckner, Richard, Doi, Takahiro S., Takahashi, Toshitada, Obata, Yuichi, Yoshioka, Katsuji, Yamamoto, Ken-ichi

“…p53 and NF-κB RelA are activated by various genotoxic agents and mutually suppress each other's ability to activate transcription, most likely through…”
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The NF-kappaB RelA subunit confers resistance to Leishmania major by inducing nitric oxide synthase 2 and Fas expression but not Th1 differentiation by Mise-Omata, Setsuko, Kuroda, Etsushi, Sugiura, Tsutomu, Yamashita, Uki, Obata, Yuichi, Doi, Takahiro S

“…Although the NF-kappaB transcription factors participate in both innate and adaptive immune responses, little is known about the role of the RelA subunit…”
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The NF-{kappa}B RelA Subunit Confers Resistance to Leishmania major by Inducing Nitric Oxide Synthase 2 and Fas Expression but Not Th1 Differentiation by Mise-Omata, Setsuko, Kuroda, Etsushi, Sugiura, Tsutomu, Yamashita, Uki, Obata, Yuichi, Doi, Takahiro S

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A Proximal {kappa}B Site in the IL-23 p19 Promoter Is Responsible for RelA- and c-Rel-Dependent Transcription by Mise-Omata, Setsuko, Kuroda, Etsushi, Niikura, Junko, Yamashita, Uki, Obata, Yuichi, Doi, Takahiro S

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