Search Results - "Dohnal, Jiri"

Remotely Controlled Diffusion from Magnetic Liposome Microgels by Hanuš, Jaroslav, Ullrich, Martin, Dohnal, Jiří, Singh, Mandeep, Štěpánek, František

“…The reversible, temperature-dependent change in the permeability of a phospholipid bilayer has been used for controlling the diffusion rate of encapsulated…”
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Designing a dynamic dissolution method: a review of instrumental options and corresponding physiology of stomach and small intestine by Culen, Martin, Rezacova, Anna, Jampilek, Josef, Dohnal, Jiri

“…Development of new pharmaceutical compounds and dosage forms often requires in vitro dissolution testing with the closest similarity to the human…”
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Encapsulation stability and temperature-dependent release kinetics from hydrogel-immobilised liposomes by Ullrich, Martin, Hanuš, Jaroslav, Dohnal, Jiří, Štěpánek, František

“…[Display omitted] ► Novel composite alginate–liposome hydrogel prepared. ► Influence of temperature, lipid:cholesterol ratio and osmolarity on stability…”
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Effect of process scale-up on the dissolution of granules with a high content of active pharmaceutical ingredient by Smrčka, David, Dohnal, Jiří, Štěpánek, František

“…The robustness and parametric sensitivity of a high-shear wet granulation process during scale-up were investigated for a formulation containing over 50% by…”
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Preparation of candesartan and atorvastatin nanoparticles by solvent evaporation by Vaculikova, Eliska, Grunwaldova, Veronika, Kral, Vladimir, Dohnal, Jiri, Jampilek, Josef

“…The solubility, absorption and distribution of a drug are involved in the basic aspects of oral bioavailability Solubility is an essential characteristic and…”
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ROLE OF THE INTERNATIONAL ORGANIZATIONS IN PREVENTING THE COUNTERFEIT MEDICINES ENTRY INTO THE WORLD MARKETS by Stukina, Valeryia, Dohnal, Jiri, Saloun, Jan

“…30 years have passed since Conference of Experts on the Rational Use of Drugs was held in Nairobi, Kenya, from 25 to 29 November 1985, where the problem of…”
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Primary investigation of the preparation of nanoparticles by precipitation by Vaculikova, Eliska, Grunwaldova, Veronika, Kral, Vladimir, Dohnal, Jiri, Jampilek, Josef

“…The absorption, distribution, biotransformation and excretion of a drug involve its transport across cell membranes. This process is essential and influenced…”
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Active tectonics research using trenching technique on the south-eastern section of the Sudetic Marginal Fault (NE Bohemian Massif, central Europe) by Štěpančíková, Petra, Hók, Jozef, Nývlt, Daniel, Dohnal, Jiří, Sýkorová, Ivana, Stemberk, Josef

“…The NW–SE striking Sudetic Marginal Fault (SMF) is one of the most conspicuous tectonic structures in central Europe. It controls the pronounced morphotectonic…”
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Rhodanineacetic acid derivatives as potential drugs: preparation, hydrophobic properties and antifungal activity of (5-arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acids by Dolezel, Jan, Hirsova, Petra, Opletalova, Veronika, Dohnal, Jiri, Marcela, Vejsova, Kunes, Jiri, Jampilek, Josef

“…Some [(5Z)-(5-arylalkylidene-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)]acetic acids were prepared as potential antifungal compounds. The general synthetic approach…”
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Development of In Vitro-In Vivo Correlation/Relationship Modeling Approaches for Immediate Release Formulations Using Compartmental Dynamic Dissolution Data from “Golem”: A Novel Apparatus by Mendyk, Aleksander, Jachowicz, Renata, Polak, Sebastian, Tuszyński, Paweł K., Čulen, Martin, Dohnal, Jiri

“…Different batches of atorvastatin, represented by two immediate release formulation designs, were studied using a novel dynamic dissolution apparatus,…”
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Synthesis, antimycobacterial, antifungal and photosynthesis-inhibiting activity of chlorinated N-phenylpyrazine-2-carboxamides by Dolezal, Martin, Zitko, Jan, Osicka, Zdenek, Kunes, Jiri, Vejsova, Marcela, Buchta, Vladimir, Dohnal, Jiri, Jampilek, Josef, Kralova, Katarina

“…A series of sixteen pyrazinamide analogues with the -CONH- linker connecting the pyrazine and benzene rings was synthesized by the condensation of chlorides of…”
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Investigating biological activity spectrum for novel styrylquinazoline analogues by Jampilek, Josef, Musiol, Robert, Finster, Jacek, Pesko, Matus, Carroll, James, Kralova, Katarina, Vejsova, Marcela, O'Mahony, Jim, Coffey, Aidan, Dohnal, Jiri, Polanski, Jaroslaw

“…In this study, series of ring-substituted 2-styrylquinazolin-4(3H)-one and 4-chloro-2-styrylquinazoline derivatives were prepared. The syntheses of the…”
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Titania-based stationary phase in separation of ondansetron and its related compounds by Žižkovský, Václav, Kučera, Radim, Klimeš, Jiří, Dohnal, Jiří

“…Improvements in stationary phase stability have been and remain a great task for research of new stationary phases. Metal oxide-based stationary phases appear…”
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Product of alaptide synthesis: Determination of the absolute configuration by Julínek, Ondřej, Setnička, Vladimír, Řezáčová, Anna, Dohnal, Jiří, Vosátka, Václav, Urbanová, Marie

“…Alaptide is the active substance of the veterinary dermatological ointment ALAPTID and a potential drug in human medicine. Electronic circular dichroism…”
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The application of electrical resistivity tomography and gravimetric survey as useful tools in an active tectonics study of the Sudetic Marginal Fault (Bohemian Massif, central Europe) by Štěpančíková, Petra, Dohnal, Jiří, Pánek, Tomáš, Łój, Monika, Smolková, Veronika, Šilhán, Karel

“…This paper presents the results of two separate geophysical investigations undertaken across the Sudetic Marginal Fault zone in the Bohemian Massif. This fault…”
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HPLC study of glimepiride under hydrolytic stress conditions by Kovařı́ková, Petra, Klimeš, Jiřı́, Dohnal, Jiřı́, Tisovská, Lucie

“…Glimepiride is a modern hypoglycaemic agent, which belongs to the group of sulfonylurea derivates. In this paper, simple, specific and accurate RP-HPLC method…”
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In Vitro Permeation of Micronized and Nanonized Alaptide from Semisolid Formulations by Jampilek, Josef, Dohnal, Jiri, Coufalova, Lenka, Cernikova, Aneta, Opatrilova, Radka

“…This study is focused on in vitro permeation of the original Czech compound, a skin/mucosa tissue regeneration promoter, known under the international…”
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Ring-substituted 4-hydroxy-1H-quinolin-2-ones: preparation and biological activity by Jampilek, Josef, Musiol, Robert, Pesko, Matus, Kralova, Katarina, Vejsova, Marcela, Carroll, James, Coffey, Aidan, Finster, Jacek, Tabak, Dominik, Niedbala, Halina, Kozik, Violetta, Polanski, Jaroslaw, Csollei, Jozef, Dohnal, Jiri

“…In the study, a series of twelve ring-substituted 4-hydroxy-1H-quinolin-2-one derivatives were prepared. The procedures for synthesis of the compounds are…”
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New propanoyloxy derivatives of 5β-cholan-24-oic acid as drug absorption modifiers by Coufalová, Lenka, Mrózek, Lech, Rárová, Lucie, Plaček, Lukáš, Opatřilová, Radka, Dohnal, Jiří, Král’ová, Katarína, Paleta, Oldřich, Král, Vladimír, Drašar, Pavel, Jampílek, Josef

“…[Display omitted] ► 5β-Cholan-24-oic acid derivatives: synthesis, lipophilicity, solubility. ► Transdermal penetration enhancers. ► Intestinal absorption…”
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New polyfluorothiopropanoyloxy derivatives of 5β-cholan-24-oic acid designed as drug absorption modifiers by Mrózek, Lech, Coufalová, Lenka, Rárová, Lucie, Plaček, Lukáš, Opatřilová, Radka, Dohnal, Jiří, Kráľová, Katarína, Paleta, Oldřich, Král, Vladimír, Drašar, Pavel, Jampílek, Josef

“…•5β-Cholan-24-oic acid derivatives: synthesis, lipophilicity, solubility.•Transdermal penetration enhancers.•Intestinal absorption promoters.•In vitro…”
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