Search Results - "Doffe, Flora"

Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene by Doffe, Flora, Carbonnier, Vincent, Tissier, Manon, Leroy, Bernard, Martins, Isabelle, Mattsson, Johanna S. M., Micke, Patrick, Pavlova, Sarka, Pospisilova, Sarka, Smardova, Jana, Joerger, Andreas C., Wiman, Klas G., Kroemer, Guido, Soussi, Thierry

“…Infrequent and rare genetic variants in the human population vastly outnumber common ones. Although they may contribute significantly to the genetic basis of a…”
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Jejunum-derived NF-κB reporter organoids as 3D models for the study of TNF-alpha-induced inflammation by Daghero, Hellen, Doffe, Flora, Varela, Belén, Yozzi, Victoria, Verdes, José Manuel, Crispo, Martina, Bollati-Fogolín, Mariela, Pagotto, Romina

“…Inflammation is an important process for epithelial barrier protection but when uncontrolled, it can also lead to tissue damage. The nuclear factor-kappa light…”
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Evaluating immune response in vitro in a relevant microenvironment: a high-throughput microfluidic model for clinical screening by Doffe, Flora, Fuoco, Layla, Michels, Judith, Jernström, Sandra, Tomasi, Raphael, Savagner, Pierre

“…Functional screening of new pharmaceutical compounds requires clinically relevant models to monitor essential cellular and immune responses during cancer…”
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TP53_PROF: a machine learning model to predict impact of missense mutations in TP53 by Ben-Cohen, Gil, Doffe, Flora, Devir, Michal, Leroy, Bernard, Soussi, Thierry, Rosenberg, Shai

“…Abstract Correctly identifying the true driver mutations in a patient’s tumor is a major challenge in precision oncology. Most efforts address frequent…”
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Designing Organoid Models to Monitor Cancer Progression, Plasticity and Resistance: The Right Set Up for the Right Question by Doffe, Flora, Bonini, Fabien, Lakis, Emile, Terry, Stéphane, Chouaib, Salem, Savagner, Pierre

“…The recent trend in 3D cell modeling has fostered the emergence of a wide range of models, addressing very distinct goals ranging from the fundamental…”
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