Search Results - "Doerrler, William T"

A link between pH homeostasis and colistin resistance in bacteria by Panta, Pradip R., Doerrler, William T.

“…Colistin resistance is complex and multifactorial. DbcA is an inner membrane protein belonging to the DedA superfamily required for maintaining extreme…”
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Members of the Conserved DedA Family Are Likely Membrane Transporters and Are Required for Drug Resistance in Escherichia coli by KUMAR, Sujeet, DOERRLER, William T

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Escherichia coli YqjA, a Member of the Conserved DedA/Tvp38 Membrane Protein Family, Is a Putative Osmosensing Transporter Required for Growth at Alkaline pH by Kumar, Sujeet, Doerrler, William T

“…The ability to persist and grow under alkaline conditions is an important characteristic of many bacteria. In order to survive at alkaline pH, Escherichia coli…”
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A Burkholderia thailandensis DedA Family Membrane Protein Is Required for Proton Motive Force Dependent Lipid A Modification by Panta, Pradip R, Doerrler, William T

“…The DedA family is a conserved membrane protein family found in most organisms. A DedA family protein, named DbcA, is required for high-level colistin…”
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New Functions for the Ancient DedA Membrane Protein Family by Doerrler, William T, Sikdar, Rakesh, Kumar, Sujeet, Boughner, Lisa A

“…The DedA protein family is a highly conserved and ancient family of membrane proteins with representatives in most sequenced genomes, including those of…”
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A Klebsiella pneumoniae DedA family membrane protein is required for colistin resistance and for virulence in wax moth larvae by Tiwari, Vijay, Panta, Pradip R., Billiot, Caitlin E., Douglass, Martin V., Herrera, Carmen M., Trent, M. Stephen, Doerrler, William T.

“…Ineffectiveness of carbapenems against multidrug resistant pathogens led to the increased use of colistin (polymyxin E) as a last resort antibiotic. A gene…”
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A DedA Family Membrane Protein Is Required for Burkholderia thailandensis Colistin Resistance by Panta, Pradip R, Kumar, Sujeet, Stafford, Caroline F, Billiot, Caitlin E, Douglass, Martin V, Herrera, Carmen M, Trent, M Stephen, Doerrler, William T

“…Colistin is a "last resort" antibiotic for treatment of infections caused by some multidrug resistant Gram-negative bacterial pathogens. Resistance to colistin…”
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Multiple Envelope Stress Response Pathways Are Activated in an Escherichia coli Strain with Mutations in Two Members of the DedA Membrane Protein Family by Sikdar, Rakesh, Simmons, Angelica R, Doerrler, William T

“…We have reported that simultaneous deletion of two Escherichia coli genes, yqjA and yghB, encoding related and conserved inner membrane proteins belonging to…”
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Inefficient Tat-Dependent Export of Periplasmic Amidases in an Escherichia coli Strain with Mutations in Two DedA Family Genes by SIKDAR, Rakesh, DOERRLER, William T

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Structural modification of the tripeptide KPV by reductive "glycoalkylation" of the lysine residue by Songok, Abigael C, Panta, Pradip, Doerrler, William T, Macnaughtan, Megan A, Taylor, Carol M

“…Peptides that exhibit enzymatic or hormonal activities are regulatory factors and desirable therapeutic drugs because of their high target specificity and…”
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Klebsiella pneumoniae DedA family proteins have redundant roles in divalent cation homeostasis and resistance to phagocytosis by Tiwari, Vijay, Sharma, Amit, Braga, Reygan, Garcia, Emily, Appiah, Ridhwana, Fleeman, Renee, Abuaita, Basel H, Patrauchan, Marianna, Doerrler, William T

“…The DedA superfamily is a highly conserved family of membrane proteins. Deletion of and , encoding related DedA family proteins, results in sensitivity to…”
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MsbA-dependent Translocation of Lipids across the Inner Membrane of Escherichia coli by Doerrler, William T, Gibbons, Henry S, Raetz, Christian R H

“…MsbA is an essential ABC transporter in Escherichia coli required for exporting newly synthesized lipids from the inner to the outer membrane. It remains…”
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ATPase Activity of the MsbA Lipid Flippase of Escherichia coli by Doerrler, William T., Raetz, Christian R.H.

“…Escherichia coli MsbA, the proposed inner membrane lipid flippase, is an essential ATP-binding cassette transporter protein with homology to mammalian…”
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Loss of Outer Membrane Proteins without Inhibition of Lipid Export in an Escherichia coli YaeT Mutant by Doerrler, William T., Raetz, Christian R.H.

“…Escherichia coli yaeT encodes an essential, conserved outer membrane (OM) protein that is an ortholog of Neisseria meningitidis Omp85. Conflicting data with N…”
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BB0250 of Borrelia burgdorferi Is a Conserved and Essential Inner Membrane Protein Required for Cell Division by Liang, Fang Ting, Xu, Qilong, Sikdar, Rakesh, Xiao, Ying, Cox, James S, Doerrler, William T

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Temperature Sensitivity and Cell Division Defects in an Escherichia coli Strain with Mutations in yghB and yqjA, Encoding Related and Conserved Inner Membrane Proteins by THOMPKINS, Kandi, CHATTOPADHYAY, Ballari, YING XIAO, HENK, Margaret C, DOERRLER, William T

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Enteric YaiW Is a Surface-Exposed Outer Membrane Lipoprotein That Affects Sensitivity to an Antimicrobial Peptide by Arnold, Markus F. F, Caro-Hernandez, Paola, Tan, Karen, Runti, Giulia, Wehmeier, Silvia, Scocchi, Marco, Doerrler, William T, Walker, Graham C, Ferguson, Gail P

“…yaiW is a previously uncharacterized gene found in enteric bacteria that is of particular interest because it is located adjacent to the sbmA gene, whose bacA…”
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Density Gradient Enrichment of Escherichia coli Conditional msbA Mutants by Doerrler, William T

“…Insight into the mechanism of lipid transport to the outer membrane of gram-negative bacteria has been hampered by the lack of an effective genetic screen for…”
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Transcription Factor PecS Mediates Agrobacterium fabrum Fitness and Survival by Nwokocha, George C, Adhikari, Prava, Iqbal, Asif, Elkholy, Hannah, Doerrler, William T, Larkin, John C, Grove, Anne

“…The transcriptional regulator PecS is encoded by select bacterial pathogens. For instance, in the plant pathogen Dickeya dadantii, PecS controls a range of…”
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Chemical or Genetic Alteration of Proton Motive Force Results in Loss of Virulence of Burkholderia glumae, the Cause of Rice Bacterial Panicle Blight by Iqbal, Asif, Panta, Pradip R, Ontoy, John, Bruno, Jobelle, Ham, Jong Hyun, Doerrler, William T

“…Rice is an important source of food for more than half of the world's population. Bacterial panicle blight (BPB) is a disease of rice characterized by grain…”
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