Search Results - "Doerig, C"
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Systematic review with meta‐analysis: self‐expanding metal stents in patients with cirrhosis and severe or refractory oesophageal variceal bleeding
Published in Alimentary pharmacology & therapeutics (01-12-2015)“…Summary Background The prognosis of patients with cirrhosis and acute variceal bleeding is very poor when the standard‐of‐care fails to control bleeding. New…”
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Target fishing reveals PfPYK-1 and PfRab6 as potential targets of an antiplasmodial 4-anilino-2-trichloromethylquinazoline hit compound
Published in Bioorganic & medicinal chemistry (15-03-2024)“…[Display omitted] We present investigations about the mechanism of action of a previously reported 4-anilino-2-trichloromethylquinazoline antiplasmodial…”
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HEV as a cause of acute hepatitis acquired in Switzerland
Published in Journal of hepatology (2017)Get full text
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P701 AUTOCHTHONOUS ACUTE HEPATITIS E IN SWITZERLAND: INCREASED RATE OF SEVERE MANIFESTATION IN MEN >50 YEARS
Published in Journal of hepatology (01-04-2014)Get full text
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The Toxoplasma gondii plastid replication and repair enzyme complex, PREX
Published in Parasitology (01-06-2009)“…A plastid-like organelle, the apicoplast, is essential to the majority of medically and veterinary important apicomplexan protozoa including Toxoplasma gondii…”
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Protein kinases as drug targets in parasitic protozoa
Published in Trends in Parasitology (01-08-2002)“…The importance of protein kinases in cell signaling and cell cycle control has led to detailed structural and functional studies in various eukaryotes, and…”
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Plasmodium falciparum glycogen synthase kinase-3: molecular model, expression, intracellular localisation and selective inhibitors
Published in BBA - Proteins and Proteomics (11-03-2004)“…Worldwide increasing resistance of Plasmodium falciparum to common anti-malaria agents calls for the urgent identification of new drugs. Glycogen synthase…”
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Antiplasmodial activities of homogentisic acid derivative protein kinase inhibitors isolated from a Vanuatu marine sponge Pseudoceratina sp
Published in Marine drugs (23-11-2009)“…As part of our search for new antimalarial drugs in South Pacific marine sponges, we have looked for inhibitors of Pfnek-1, a specific protein kinase of…”
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Signalling in malaria parasites – The MALSIG consortium
Published in Parasite (Paris) (01-09-2009)“…Depending on their developmental stage in the life cycle, malaria parasites develop within or outside host cells, and in extremely diverse contexts such as the…”
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How best to unify crowding?
Published in Current biology (09-05-2016)“…In crowding, the perception of an object deteriorates in the presence of nearby elements. Obviously, crowding is a ubiquitous phenomenon, as elements are…”
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A MAP kinase homologue from the human malaria parasite, Plasmodium falciparum
Published in Gene (24-10-1996)“…Pfmap-1, a gene encoding a novel protein kinase, has been identified in the human malaria parasite Plasmodium falciparum, using the polymerase chain reaction…”
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Protein kinases as targets for anti-parasitic chemotherapy
Published in BBA - Proteins and Proteomics (11-03-2004)“…Parasitic protozoa infecting humans have a staggering impact on public health, especially in the developing world. Furthermore, several protozoan species are…”
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Book Review Journal Article -
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In vitro activities of two antimitotic compounds, pancratistatin and 7-deoxynarciclasine, against Encephalitozoon intestinalis, a microsporidium causing infections in humans
Published in Antimicrobial agents and chemotherapy (01-12-2001)“…The antiparasitic effect of a collection of compounds with antimitotic activity has been tested on a mammalian cell line infected with Encephalitozoon…”
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Management of viral hepatitis in patients with haematological malignancy and in patients undergoing haemopoietic stem cell transplantation: recommendations of the 5th European Conference on Infections in Leukaemia (ECIL-5)
Published in The Lancet infectious diseases (01-05-2016)“…Summary Viral hepatitis affects millions of people worldwide, and host immunity is the key determinant of patient outcome. Viral hepatitis can be life…”
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Nonstructural protein of parvoviruses B19 and minute virus of mice controls transcription
Published in Journal of Virology (01-01-1990)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Production of Sm37-GAPDH, a major therapeutical target in human schistosomiasis
Published in Biotechnology and bioengineering (20-04-2000)“…Glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) is a key enzyme in the glycolytic metabolism and the production of energy. This probably explains why GAPDH…”
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