Search Results - "Doepker, Laura"

Diversity and Function of Maternal HIV-1-Specific Antibodies at the Time of Vertical Transmission by Doepker, Laura E, Simonich, Cassandra A, Ralph, Duncan, Shipley, Mackenzie M, Garrett, Meghan, Gobillot, Theodore, Vigdorovich, Vladimir, Sather, D Noah, Nduati, Ruth, Matsen, 4th, Frederick A, Overbaugh, Julie M

“…Infants of HIV-positive mothers can acquire HIV infection by various routes, but even in the absence of antiviral treatment, the majority of these infants do…”
Get full text

Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage by Simonich, Cassandra A., Doepker, Laura, Ralph, Duncan, Williams, James A., Dhar, Amrit, Yaffe, Zak, Gentles, Lauren, Small, Christopher T., Oliver, Brian, Vigdorovich, Vladimir, Mangala Prasad, Vidya, Nduati, Ruth, Sather, D. Noah, Lee, Kelly K., Matsen IV, Frederick A., Overbaugh, Julie

“…HIV-infected infants develop broadly neutralizing plasma responses with more rapid kinetics than adults, suggesting the ontogeny of infant responses could…”
Get full text

Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection by Shipley, Mackenzie M, Mangala Prasad, Vidya, Doepker, Laura E, Dingens, Adam, Ralph, Duncan K, Harkins, Elias, Dhar, Amrit, Arenz, Dana, Chohan, Vrasha, Weight, Haidyn, Mandaliya, Kishor, Bloom, Jesse D, Matsen, Frederick A, Lee, Kelly K, Overbaugh, Julie M

“…Stimulating broadly neutralizing antibodies (bnAbs) directly from germline remains a barrier for HIV vaccines. HIV superinfection elicits bnAbs more frequently…”
Get full text

Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies by Doepker, Laura E, Danon, Sonja, Harkins, Elias, Ralph, Duncan K, Yaffe, Zak, Garrett, Meghan E, Dhar, Amrit, Wagner, Cassia, Stumpf, Megan M, Arenz, Dana, Williams, James A, Jaoko, Walter, Mandaliya, Kishor, Lee, Kelly K, Matsen, 4th, Frederick A, Overbaugh, Julie M

“…A prerequisite for the design of an HIV vaccine that elicits protective antibodies is understanding the developmental pathways that result in desirable…”
Get full text

Reconstruction of a polyclonal ADCC antibody repertoire from an HIV-1 non-transmitting mother by Yaffe, Zak A., Ding, Shilei, Sung, Kevin, Chohan, Vrasha, Marchitto, Lorie, Doepker, Laura, Ralph, Duncan, Nduati, Ruth, Matsen, Frederick A., Finzi, Andrés, Overbaugh, Julie

“…Human natural history and vaccine studies support a protective role of antibody dependent cellular cytotoxicity (ADCC) activity against many infectious…”
Get full text

A diverse collection of B cells responded to HIV infection in infant BG505 by Simonich, Cassandra, Shipley, Mackenzie M., Doepker, Laura, Gobillot, Theodore, Garrett, Meghan, Cale, Evan M., Hennessy, Brianna, Itell, Hannah, Chohan, Vrasha, Doria-Rose, Nicole, Nduati, Ruth, Overbaugh, Julie

“…Increasing evidence suggests infants develop unique neutralizing antibody (nAb) responses to HIV compared to adults. Here, we dissected the nAb response of an…”
Get full text