Search Results - "Dodwell, D. J."

Immediate and delayed autologous abdominal microvascular flap breast reconstruction in patients receiving adjuvant, neoadjuvant or no radiotherapy: a meta‐analysis of clinical and quality‐of‐life outcomes by Khajuria, A., Charles, W. N., Prokopenko, M., Beswick, A., Pusic, A. L., Mosahebi, A., Dodwell, D. J., Winters, Z. E.

“…Background Effects of postmastectomy radiotherapy (PMRT) on autologous breast reconstruction (BRR) are controversial regarding surgical complications, cosmetic…”
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Dose-finding study of weekly docetaxel, epirubicin and capecitabine, as first-line treatment in advanced breast cancer by Waters, S. H, Gillibrand, A, Berry, H, Kumar, S, Velikova, G, Dodwell, D. J, Perren, Timothy J

“…Background Combinations of anthracycline, taxane and fluoropyrimidine are highly active in advanced breast cancer (ABC). In a phase II study of epirubicin 50…”
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Adjuvant cytotoxic chemotherapy for early breast cancer: doubts and decisions by Dodwell, DJ

“…Conflicting views about the value of adjuvant cytotoxic chemotherapy (ACC) persist. Dodwell notes that to target ACC more effectively, pathological and…”
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Malignant bone resorption: cellular and biochemical mechanisms by Dodwell, D J

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A randomized, open, parallel-group trial to compare the endocrine effects of oral anastrozole (Arimidex®) with intramuscular formestane in postmenopausal women with advanced breast cancer by Vorobiof, D. A., Kleeberg, U. R., Perez-Carrion, R., Dodwell, D. J., Robertson, J. F. R., Calvo, L., Dowsett, M., Clack, G.

“…Background: This study provides a direct randomized comparison of a new-generation, non-steroidal aromatase inhibitor, anastrozole (Arimidex®), with a…”
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High dose, dose-intensive chemotherapy with doxorubicin and cyclophosphamide for the treatment of advanced breast cancer by FERGUSON, J. E, DODWELL, D. J, SEYMOUR, A.-M, RICHARDS, M. A, HOWELL, A

“…Eighteen patients with advanced breast cancer were commenced on treatment with high dose doxorubicin (100 mg m-2) or doxorubicin (100 mg m-2) and…”
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A Randomised Study of Whole-breast vs Tumour-bed Irradiation After Local Excision and Axillary Dissection for Early Breast Cancer by Dodwell, D.J., Dyker, K., Brown, J., Hawkins, K., Cohen, D., Stead, M., Ash, D.

“…Whole-breast radiotherapy (WBRT) after conservative surgery for early breast cancer is a routine standard of care. Despite this, a number of uncertainties in…”
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Cytotoxic drugs: the search for dose response by Dodwell, D J

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Aromatase inhibitors and musculoskeletal symptoms by Khanduri, S, Dodwell, D.J

“…Abstract Aims Recent evidence shows aromatase inhibitors (AIs) to be of benefit over tamoxifen in the adjuvant setting. It is also apparent that…”
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Dose intensity in cancer chemotherapy by DODWELL, D. J, GURNEY, H, THATCHER, N

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Morbidity of tamoxifen–perceptions of patients and healthcare professionals by Adlard, J.W., Campbell, J., Bishop, J.M., Dodwell, D.J.

“…There is little published data comparing patients' and doctors' perceptions of tamoxifen-related morbidity and toxicity, in particular in terms of side-effects…”
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A randomised comparison of oestrogen suppression with anastrozole and formestane in postmenopausal patients with advanced breast cancer by Kleeberg, U R, Dowsett, M, Carrion, R P, Dodwell, D J, Vorobiof, D A, Aparicio, L A, Robertson, J F

“…The relative efficacy and tolerability of the aromatase inhibitors anastrozole (Arimidex) and formestane are assessed in a direct comparative trial in…”
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The potential for proteinase inhibition in cancer treatment by Dodwell, D J, Howell, A

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Proteinase Inhibitors in Malignancy: Therapeutic Promise or Another White Elephant? by Dodwell, D J

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The clearance and bioavailability of pamidronate in patients with breast cancer and bone metastases by DALEY-YATES, P. T, DODWELL, D. J, PONGCHAIDECHA, M, COLEMAN, R. E, HOWELL, A

“…The pharmacokinetics and bioavailability of pamidronate were assessed in patients with breast cancer, 6 subjects received the drug intravenously and 7 orally…”
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Reduction in calcium excretion in women with breast cancer and bone metastases using the oral bisphosphonate pamidronate by DODWELL, D. J, HOWELL, A, FORD, J

“…The bisphosphonate pamidronate (3 amino-1, 1-hydroxypropylidene bisphosphonate (APD), Ciba-Geigy) is a powerful inhibitor of osteoclast function and has been…”
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Etoposide-related myocardial infarction by Airey, C.L., Dodwell, D.J., Joffe, J.K., Jones, W.G.

“…The occurrence of a myocardial infarction is reported after chemotherapy containing etoposide, in a man with no risk factors for coronary heart disease…”
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Skin telangiectasia: The influence of radiation dose delivery parameters in the conservative management of early breast cancer by Dodwell, D.J., Povall, J., Gerrard, G., Eastwood, A., Langlands, A.

“…A retrospective analysis was performed to study the occurrence of skin telangiectasia in patients with conservatively treated early breast cancer who were…”
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Infusion rate and pharmacokinetics of intravenous pamidronate in the treatment of tumour-induced hypercalcaemia by Dodwell, D. J., Howell, A., Morton, A. R., Daley-Yates, P. T., Hoggarth, C. R.

“…We report the results of two consecutive randomized studies in the treatment of malignant hypercalcaemia with intravenous pamidronate. Overall normocalcaemia…”
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Response after withdrawal of tamoxifen and progestogens in advanced breast cancer by Howell, A, Dodwell, D J, Anderson, H, Redford, J

“…Tumor response after withdrawal of endocrine therapy for advanced breast cancer with estrogens and androgens is well described. There have been few reports of…”
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