Search Results - "Dodson, R. Blair"
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Pharmacological activation of peroxisome proliferator‐activated receptor γ (PPAR‐γ) protects against hypoxia‐associated fetal growth restriction
Published in The FASEB journal (01-08-2019)“…ABSTRACT The hypoxia of high‐altitude (HA) residence increases the risk of intrauterine growth restriction (IUGR) and preeclampsia 3‐fold, augmenting perinatal…”
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Intrauterine growth restriction influences vascular remodeling and stiffening in the weanling rat more than sex or diet
Published in American journal of physiology. Heart and circulatory physiology (01-02-2017)“…Intrauterine growth restriction (IUGR) increases the incidence of adult cardiovascular disease (CVD). The sex-specific developmental mechanisms for…”
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Thoracic and abdominal aortas stiffen through unique extracellular matrix changes in intrauterine growth restricted fetal sheep
Published in American journal of physiology. Heart and circulatory physiology (01-02-2014)“…Intrauterine growth restriction (IUGR) is a fetal complication of pregnancy epidemiologically linked to cardiovascular disease in the newborn later in life…”
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Dynamic Changes in Aortic Vascular Stiffness in Patients Bridged to Transplant With Continuous-Flow Left Ventricular Assist Devices
Published in JACC. Heart failure (01-06-2017)“…Abstract Objectives The aim of this study was to measure aortic vascular stiffness from orthotopic heart transplant (OHT) patients exposed to varying types of…”
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Large artery stiffening and mortality in a rat model of early vascular remodeling induced by intrauterine growth restriction and a high‐fat diet
Published in Physiological reports (01-12-2022)“…Intrauterine growth restriction (IUGR) and exposure to a high‐fat diet (HFD) independently increase the risk of cardiovascular disease (CVD) and…”
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Changes in Aortic Wall Structure, Composition, and Stiffness With Continuous-Flow Left Ventricular Assist Devices: A Pilot Study
Published in Circulation. Heart failure (01-09-2015)“…The effects of nonpulsatile flow on the aorta are unknown. Our aim was to examine the structure of the aorta from patients with continuous-flow left…”
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Impact of diet on the persistence of early vascular remodeling and stiffening induced by intrauterine growth restriction and a maternal high-fat diet
Published in American journal of physiology. Heart and circulatory physiology (01-08-2019)“…Intrauterine growth restriction (IUGR) and maternal high-fat diet (HFD) independently predispose offspring to hypertension. In a rat model, IUGR more so than…”
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Chronic intrauterine pulmonary hypertension increases main pulmonary artery stiffness and adventitial remodeling in fetal sheep
Published in American journal of physiology. Lung cellular and molecular physiology (01-12-2014)“…Persistent pulmonary hypertension of the newborn (PPHN) is a clinical syndrome that is characterized by high pulmonary vascular resistance due to changes in…”
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Intrauterine growth restriction decreases NF-κB signaling in fetal pulmonary artery endothelial cells of fetal sheep
Published in American journal of physiology. Lung cellular and molecular physiology (01-09-2018)“…Intrauterine growth restriction (IUGR) in premature newborns increases the risk for bronchopulmonary dysplasia, a chronic lung disease characterized by…”
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Sodium nitrite de-stiffening of large elastic arteries with aging: Role of normalization of advanced glycation end-products
Published in Experimental gerontology (01-08-2012)“…We tested the hypothesis that sodium nitrite treatment reverses large elastic artery stiffening in old mice via reductions in collagen I, increases in elastin…”
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Intrauterine endotoxin-induced impairs pulmonary vascular function and right ventricular performance in infant rats and improvement with early vitamin D therapy
Published in American journal of physiology. Lung cellular and molecular physiology (15-12-2015)“…High pulmonary vascular resistance (PVR), proximal pulmonary artery (PA) impedance, and right ventricular (RV) afterload due to remodeling contribute to the…”
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Antenatal Vitamin D Preserves Placental Vascular and Fetal Growth in Experimental Chorioamnionitis Due to Intra-amniotic Endotoxin Exposure
Published in American journal of perinatology (01-11-2018)“…Chorioamnionitis (CA) is associated with a high risk for the development of bronchopulmonary dysplasia (BPD) after preterm birth, but mechanisms that increase…”
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Hyperelastic remodeling in the intrauterine growth restricted (IUGR) carotid artery in the near-term fetus
Published in Journal of biomechanics (15-03-2013)“…Abstract A constitutive model for a fiber reinforced hyperelastic material was applied to understand arterial fiber remodeling in a sheep model of Intrauterine…”
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Determination of hyperelastic properties for umbilical artery in preeclampsia from uniaxial extension tests
Published in European journal of obstetrics & gynecology and reproductive biology (01-07-2013)“…Abstract Objective Preeclampsia often results in altered hemodynamics and structurally remodeled umbilical arteries in the fetus – alterations that may be…”
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