Search Results - "Dodson, Eleanor J."

Structural framework for DNA translocation via the viral portal protein by Lebedev, Andrey A, Krause, Margret H, Isidro, Anabela L, Vagin, Alexei A, Orlova, Elena V, Turner, Joanne, Dodson, Eleanor J, Tavares, Paulo, Antson, Alfred A

“…Tailed bacteriophages and herpesviruses load their capsids with DNA through a tunnel formed by the portal protein assembly. Here we describe the X‐ray…”
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crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity by Bolam, David N, Roberts, Shirley, Proctor, Mark R, Turkenburg, Johan P, Dodson, Eleanor J, Martinez-Fleites, Carlos, Yang, Min, Davis, Benjamin G, Davies, Gideon J, Gilbert, Harry J

“…Glycosylation of macrolide antibiotics confers host cell immunity from endogenous and exogenous agents. The Streptomyces antibioticus glycosyltransferases,…”
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Structural and Functional Analysis of a Conjugated Bile Salt Hydrolase from Bifidobacterium longum Reveals an Evolutionary Relationship with Penicillin V Acylase by Kumar, R. Suresh, Brannigan, James A., Prabhune, Asmita A., Pundle, Archana V., Dodson, Guy G., Dodson, Eleanor J., Suresh, C.G.

“…Bile salt hydrolase (BSH) is an enzyme produced by the intestinal microflora that catalyzes the deconjugation of glycine- or taurine-linked bile salts. The…”
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Novel Pentameric Structure of the Diarrhea-Inducing Region of the Rotavirus Enterotoxigenic Protein NSP4 by CHACKO, Anita R, ARIFULLAH, Mohammed, SASTRI, Narayan P, JEYAKANTHAN, Jeyaraman, UENO, Go, SEKAR, Kanagaraj, READ, Randy J, DODSON, Eleanor J, RAO, Durga C, SUGUNA, Kaza

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanism by Gamble, Michael, Künze, Georg, Dodson, Eleanor J, Wilson, Keith S, Jones, D. Dafydd

“…A distinct class of the biologically important subtilisin family of serine proteases functions exclusively within the cell and forms a major component of the…”
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Structure and Activity of a Novel Archaeal β-CASP Protein with N-Terminal KH Domains by Silva, Ana P.G., Chechik, Maria, Byrne, Robert T., Waterman, David G., Ng, C. Leong, Dodson, Eleanor J., Koonin, Eugene V., Antson, Alfred A., Smits, Callum

“…MTH1203, a β-CASP metallo-β-lactamase family nuclease from the archaeon Methanothermobacter thermautotrophicus, was identified as a putative nuclease that…”
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Overview of the CCP4 suite and current developments by Winn, Martyn D., Ballard, Charles C., Cowtan, Kevin D., Dodson, Eleanor J., Emsley, Paul, Evans, Phil R., Keegan, Ronan M., Krissinel, Eugene B., Leslie, Andrew G. W., McCoy, Airlie, McNicholas, Stuart J., Murshudov, Garib N., Pannu, Navraj S., Potterton, Elizabeth A., Powell, Harold R., Read, Randy J., Vagin, Alexei, Wilson, Keith S.

“…The CCP4 (Collaborative Computational Project, Number 4) software suite is a collection of programs and associated data and software libraries which can be…”
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Structure of a Group A Streptococcal Phage-Encoded Virulence Factor Reveals a Catalytically Active Triple-Stranded β-Helix by Nicola L. Smith, Taylor, Edward J., Anna-Marie Lindsay, Charnock, Simon J., Turkenburg, Johan P., Dodson, Eleanor J., Davies, Gideon J., Black, Gary W.

“…Streptococcus pyogenes (group A Streptococcus) causes severe invasive infections including scarlet fever, pharyngitis (streptococcal sore throat), skin…”
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Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA by Antson, Alfred A, Dodson, Eleanor J, Dodson, Guy, Greaves, Richard B, Chen, Xiao-ping, Gollnick, Paul

“…The trp RNA-binding attenuation protein (TRAP) regulates expression of the tryptophan biosynthetic genes of several bacilli by binding single-stranded RNA. The…”
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Structural dissection and high-throughput screening of mannosylglycerate synthase by Davies, Gideon J, Flint, James, Taylor, Edward, Yang, Min, Bolam, David N, Tailford, Louise E, Martinez-Fleites, Carlos, Dodson, Eleanor J, Davis, Benjamin G, Gilbert, Harry J

“…The enzymatic transfer of activated mannose yields mannosides in glycoconjugates and oligo- and polysaccharides. Yet, despite its biological necessity, the…”
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The Structure of the LysR-type Transcriptional Regulator, CysB, Bound to the Inducer, N-acetylserine by Verschueren, Koen H. G., Dodson, Eleanor J., Wilkinson, Anthony J.

“…In Escherichia coli and Salmonella typhimurium , cysteine biosynthesis requires the products of 20 or more cys genes co-ordinately regulated by CysB. Under…”
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dUTPase as a Platform for Antimalarial Drug Design: Structural Basis for the Selectivity of a Class of Nucleoside Inhibitors by Whittingham, Jean L., Leal, Isabel, Nguyen, Corinne, Kasinathan, Ganasan, Bell, Emma, Jones, Andrew F., Berry, Colin, Benito, Agustin, Turkenburg, Johan P., Dodson, Eleanor J., Perez, Luis M. Ruiz, Wilkinson, Anthony J., Johansson, Nils Gunnar, Brun, Reto, Gilbert, Ian H., Pacanowska, Dolores Gonzalez, Wilson, Keith S.

“…Pyrimidine metabolism is a major route for therapeutic intervention against malaria. Here we report inhibition and structural studies on the deoxyuridine…”
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Structure and ligand binding in the putative anti-microbial peptide transporter protein, YejA by Ackroyd, Bryony K, Dodson, Eleanor J, Mehboob, Javeria, Dowle, Adam A, Thomas, Gavin H, Wilkinson, Anthony J

“…YejABEF is an ATP-binding cassette transporter that is implicated in the sensitivity of to anti-microbial peptides, the best-characterized example being…”
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Thermostable homologues of the periplasmic siderophore‐binding protein CeuE from Geobacillus stearothermophilus and Parageobacillus thermoglucosidasius by Blagova, Elena V., Miller, Alex H., Bennett, Megan, Booth, Rosalind L., Dodson, Eleanor J., Duhme-Klair, Anne-Kathrin, Wilson, Keith S.

“…Siderophore‐binding proteins from two thermophilic bacteria, Geobacillus stearothermophilus and Parageobacillus thermoglucosidasius, were identified from a…”
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Peptide transport in Bacillus subtilis - structure and specificity in the extracellular solute binding proteins OppA and DppE by Hughes, Adam M, Darby, John F, Dodson, Eleanor J, Wilson, Samuel J, Turkenburg, Johan P, Thomas, Gavin H, Wilkinson, Anthony J

“…Peptide transporters play important nutritional and cell signalling roles in which are pronounced during stationary phase adaptations and development. Three…”
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Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin by Brzozowski, Andrzej M, Dodson, Eleanor J, Dodson, Guy G, Murshudov, Garib N, Verma, Chandra, Turkenburg, Johan P, de Bree, Frederik M, Dauter, Zbigniew

“…Human insulin-like growth factors I and II (hIGF-I, hIGF-II) are potent stimulators of cell and growth processes. They display high sequence similarity to both…”
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Molecular Mimicry Enables Competitive Recruitment by a Natively Disordered Protein by Bonsor, Daniel A, Grishkovskaya, Irina, Dodson, Eleanor J, Kleanthous, Colin

“…We report the crystal structure of the Escherichia coli TolB-Pal complex, a protein−protein complex involved in maintaining the integrity of the outer membrane…”
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Crystal structure of GerE, the ultimate transcriptional regulator of spore formation in Bacillus subtilis by Ducros, Valérie M.-A, Lewis, Richard J, Verma, Chandra S, Dodson, Eleanor J, Leonard, Gordon, Turkenburg, Johan P, Murshudov, Garib N, Wilkinson, Anthony J, Brannigan, James A

“…The small, DNA-binding protein GerE regulates gene transcription in the terminally differentiated mother-cell compartment during late stages of sporulation in…”
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Redox-switchable siderophore anchor enables reversible artificial metalloenzyme assembly by Raines, Daniel J., Clarke, Justin E., Blagova, Elena V., Dodson, Eleanor J., Wilson, Keith S., Duhme-Klair, Anne-K.

“…Artificial metalloenzymes that contain protein-anchored synthetic catalysts are attracting increasing interest. An exciting, but still unrealized advantage of…”
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Crystal structure of the putative peptide‐binding protein AppA from Clostridium difficile by Hughes, Adam, Wilson, Samuel, Dodson, Eleanor J., Turkenburg, Johan P., Wilkinson, Anthony J.

“…Peptides play an important signalling role in Bacillus subtilis, where their uptake by one of two ABC‐type oligopeptide transporters, Opp and App, is required…”
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